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SZGene - Gene overview of all published SZ-association studies for MTHFD1
View on AlzGene
View on PDGene
methylenetetrahydrofolate dehydrogenase 1
(C1-THF synthase; cytoplasmic C-1-tetrahydrofolate synthase; NADP-dependent cyclohydrolase/formyltetrahydrofolate synthetase; methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase)
Updated 11 April 2007
1. Case-Control Studies (by ethnic group)
32.2 + 11
41.2 + 10.9
if you are an author of an association study regarding this gene and do not find your study in this table or find errors in the representation of your study details.
Source of case population -> “CL” (clinic-based), “PO” (population-based), or “CO” (community-based).
Number of polymorphisms tested per gene and per sample.
Onset Age and Age:
Mean or median age at onset or examination, respectively.
Criteria used to determine SZ diagnosis -> "IIIR"(DSM-IIIR), "IV" (DSM-IV), "9" (ICD-9), "10" (ICD-10), "M" (Mixed), "RDC" (Research Diagnostic Criteria), "U" (Unknown).
Overall conclusion reached by authors of the original publication (“positive” usually indicates significant (P<0.05) association in at least one of the performed analyses, and “negative” indicates no evidence for significant association, while “trend” indicates results in between).
: Either no data provided or in case of overlap, data included in original study.
SZGene Recent Updates
An up-to-date collection of all published genetic association studies.
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