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Meta-Analysis of All Published SZ Association Studies (Case-Control Only) rs1468412
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 Polymorphism: rs1468412
 Gene: GRM3  (GLUR3; mGlu3; GPRC1C; MGLUR3)  Entrez Gene
 Protein: glutamate receptor metabotropic 3   ProteinLink
 Chromosome: 7   (View: 1  2  3  4  5  6  7  8  9  10  11  12  13  14  15  16  17  18  19  20  21  22  X  Y  MT)
 Status: Updated 22 October 2010
Gene Overview
 Polymorphism:
1) Summary of Allele and Genotype Distribution of all Published Association Studies (by Ethnic Group)
      Alleles Genotypes
  # Case-Control
Samples
  T-Allele
(frequency)
A-Allele
(frequency)
T/T
(frequency)
T/A
(frequency)
A/A
(frequency)
 Caucasian 4 SZ
CTR
0.29
0.27
0.71
0.73
159 (0.083)
188 (0.075)
779 (0.407)
975 (0.388)
976 (0.510)
1351 (0.537)
 Asian 4 SZ
CTR
0.19
0.19
0.81
0.81
129 (0.041)
119 (0.037)
959 (0.304)
998 (0.312)
2064 (0.655)
2082 (0.651)
Total 8 SZ
CTR
0.23
0.23
0.77
0.77
288 (0.057)
307 (0.054)
1738 (0.343)
1973 (0.345)
3040 (0.600)
3433 (0.601)

Meta-Analysis Methods      * New * Cumulative Meta-analysis
2) Forest plot for polymorphism  rs1468412

Please also see disclaimer for more information on these meta-analyses.


Meta-analyses have not been performed on the following polymorphisms since they lack published genotype data in at least four independent case-control samples, or the published genotype data was otherwise not eligible for inclusion (see methods for details):

rs1012973
rs10234440
rs1024516
rs10277739
rs11245618
rs13242038
rs1405874
rs1476455
rs17126
rs17676277
rs187993
rs1989796
rs19898796
rs2189812
rs2189813
rs2190299
rs2214653
rs2237554
rs2237555
rs2237561
rs2237562
rs2237565
rs2282958
rs2282960
rs2299213
rs2299214
rs2299225
rs2299231
rs6943659
rs724226
rs757656
rs7781414
rs7804100
rs802427
rs802432
rs982339

SZGene Recent Updates
SZGene Stats
Studies: 1727
Genes: 1008
Polymorphisms: 8788
Meta-analyses: 287
ALSGene
AlzGene
MSGene
PDGene
SZGene
An up-to-date collection of all published genetic association studies.
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