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Printable version
Meta-Analysis of All Published SZ Association Studies (Case-Control Only)
rs1019385
Polymorphism:
rs1019385 (200T/G)
Gene:
GRIN2B
(NR2B; hNR3; NMDAR2B)
View on AlzGene
View on PDGene
Protein:
N-methyl-D-aspartate receptor subunit 2B
Chromosome:
12
(View:
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
X
Y
MT
)
Status:
Updated 22 October 2010
Polymorphism:
rs1019385 (significant)
rs1805502
rs1806201
1) Summary of Allele and Genotype Distribution of all Published Association Studies (by Ethnic Group)
Alleles
Genotypes
# Case-Control
Samples
T-Allele
(frequency)
G-Allele
(frequency)
T/T
(frequency)
T/G
(frequency)
G/G
(frequency)
Caucasian
3
SZ
CTR
0.43
0.50
0.57
0.50
91 (0.169)
113 (0.227)
279 (0.520)
271 (0.544)
167 (0.311)
114 (0.229)
Asian
2
SZ
CTR
0.48
0.55
0.52
0.45
37 (0.247)
45 (0.296)
69 (0.460)
78 (0.513)
44 (0.293)
29 (0.191)
Total
5
SZ
CTR
0.44
0.51
0.56
0.49
128 (0.186)
158 (0.243)
348 (0.507)
349 (0.537)
211 (0.307)
143 (0.220)
Meta-Analysis Methods
* New *
Cumulative Meta-analysis
2) Forest plot for polymorphism
rs1019385 (200T/G)
Please also
see disclaimer
for more information on these meta-analyses.
Meta-analyses have not been performed on the following polymorphisms since they lack published genotype data in at least four independent case-control samples, or the published genotype data was otherwise not eligible for inclusion (see
methods
for details):
GRIN2B_5041T/G
GRIN2B_5806A/C
GRIN2B_5985C/A
GRIN2B_IVS4+40A/G
rs1008619
rs1075010
rs1125236
rs1421104
rs1805246
rs1805247 (4197T/C)
rs1805476
rs1805480
rs1805482
rs1805490
rs1805539
rs1806191 (3533G/A)
rs1806209
rs1861786
rs1981781
rs1981782
rs2041986
rs2111511
rs219872
rs219873
rs220557
rs220599
rs2268097
rs2268099
rs2268113
rs2268114
rs2268121
rs2268122
rs2268130
rs2270359
rs2284404
rs2284407
rs2284416
rs2300234
rs2300245
rs7301328 (366G/C)
rs890
SZGene Recent Updates
SZGene Stats
Studies: 1727
Genes: 1008
Polymorphisms: 8788
Meta-analyses: 287
ALSGene
AlzGene
MSGene
PDGene
SZGene
An up-to-date collection of all published genetic association studies.
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