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Meta-Analysis of All Published SZ Association Studies (Case-Control Only) BDNF_-270C/T
Back Search Methods Disclaimer Credits
 Polymorphism: BDNF_-270C/T
 Gene: BDNF  (MGC34632)  Entrez Gene    View on AlzGene   View on MSGene   View on PDGene
 Protein: brain-derived neurotrophic factor  (neurotrophin)  ProteinLink
 Chromosome: 11   (View: 1  2  3  4  5  6  7  8  9  10  11  12  13  14  15  16  17  18  19  20  21  22  X  Y  MT)
 Status: Updated 21 October 2010
Gene Overview
 Polymorphism:
1) Summary of Allele and Genotype Distribution of all Published Association Studies (by Ethnic Group)
      Alleles Genotypes
  # Case-Control
Samples
  T-Allele
(frequency)
C-Allele
(frequency)
T/T
(frequency)
T/C
(frequency)
C/C
(frequency)
 Caucasian 7 SZ
CTR
0.05
0.04
0.95
0.97
3 (0.002)
2 (0.001)
121 (0.097)
119 (0.068)
1119 (0.900)
1641 (0.931)
 Asian 3 SZ
CTR
0.03
0.03
0.97
0.97
2 (0.001)
0 (0.000)
100 (0.064)
101 (0.058)
1466 (0.935)
1630 (0.942)
Total 10 SZ
CTR
0.04
0.03
0.96
0.97
5 (0.002)
2 (0.001)
221 (0.079)
220 (0.063)
2585 (0.920)
3271 (0.936)

Meta-Analysis Methods      * New * Cumulative Meta-analysis
2) Forest plot for polymorphism BDNF_-270C/T

Please also see disclaimer for more information on these meta-analyses.


Meta-analyses have not been performed on the following polymorphisms since they lack published genotype data in at least four independent case-control samples, or the published genotype data was otherwise not eligible for inclusion (see methods for details):

BDNF_132C/T
BDNF_712G/A
BDNF_STR-down
BDNF_STR-up
ro_000011924 (SNP/Roche-ID)
rs11030101 (633T/A)
rs11030104
rs11030121
rs12273363
rs12291063
rs1491851
rs1519480
rs16917204 (11757G/C)
rs2030324
rs2049045
rs2883187
rs3750934
rs4923463
rs7103411
rs7127507
rs71971022 (2bpSTR-1040)
rs7934165
rs908867
rs988748

SZGene Recent Updates
SZGene Stats
Studies: 1727
Genes: 1008
Polymorphisms: 8788
Meta-analyses: 287
ALSGene
AlzGene
MSGene
PDGene
SZGene
An up-to-date collection of all published genetic association studies.
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