Schizophrenia Research Forum - A Catalyst for Creative Thinking
Home Your Profile Become a Member/Get Newsletter Contact Us
What's New
Recent Updates
SRF Papers
Current Papers
Search All Papers
Search Comments
News
Research News
Forums
Current Hypotheses
Idea Lab
Online Discussions
Virtual Conferences
Interviews
Tech Corner
Resources
What We Know
SchizophreniaGene
Animal Models
Drugs in Trials
Research Tools
Grants
Jobs
Conferences
Journals
Community Calendar
General Information
Community
Member Directory
Researcher Profiles
Institutes and Labs
About the Site
Mission
History
SRF Team
Advisory Board
Support Us
How to Cite
Fan (E)Mail
The Schizophrenia Research Forum web site is sponsored by NARSAD, the Brain and Behavior Research Fund, and was created with funding from the U.S. National Institute of Mental Health.
Printable version  
Meta-Analysis of All Published SZ Association Studies (Case-Control Only) BDNF_-270C/T
Back Search Methods Disclaimer Credits
 Polymorphism: BDNF_-270C/T
 Gene: BDNF  (MGC34632)  Entrez Gene    View on AlzGene   View on MSGene   View on PDGene
 Protein: brain-derived neurotrophic factor  (neurotrophin)  ProteinLink
 Chromosome: 11   (View: 1  2  3  4  5  6  7  8  9  10  11  12  13  14  15  16  17  18  19  20  21  22  X  Y  MT)
 Status: Updated 21 October 2010
Gene Overview
 Polymorphism:
1) Summary of Allele and Genotype Distribution of all Published Association Studies (by Ethnic Group)
      Alleles Genotypes
  # Case-Control
Samples		   T-Allele
(frequency)		 C-Allele
(frequency)		 T/T
(frequency)		 T/C
(frequency)		 C/C
(frequency)
 Caucasian 7 SZ
CTR		 0.05
0.04		 0.95
0.97		 3 (0.002)
2 (0.001)		 121 (0.097)
119 (0.068)		 1119 (0.900)
1641 (0.931)
 Asian 3 SZ
CTR		 0.03
0.03		 0.97
0.97		 2 (0.001)
0 (0.000)		 100 (0.064)
101 (0.058)		 1466 (0.935)
1630 (0.942)
Total 10 SZ
CTR		 0.04
0.03		 0.96
0.97		 5 (0.002)
2 (0.001)		 221 (0.079)
220 (0.063)		 2585 (0.920)
3271 (0.936)

Meta-Analysis Methods      * New * Cumulative Meta-analysis
2) Forest plot for polymorphism BDNF_-270C/T

Please also see disclaimer for more information on these meta-analyses.

Meta-analyses have not been performed on the following polymorphisms since they lack published genotype data in at least four independent case-control samples, or the published genotype data was otherwise not eligible for inclusion (see methods for details):

BDNF_132C/T
BDNF_712G/A
BDNF_STR-down
BDNF_STR-up
ro_000011924 (SNP/Roche-ID)
rs11030101 (633T/A)
rs11030104
rs11030121
rs12273363
rs12291063
rs1491851
rs1519480
rs16917204 (11757G/C)
rs2030324
rs2049045
rs2883187
rs3750934
rs4923463
rs7103411
rs7127507
rs71971022 (2bpSTR-1040)
rs7934165
rs908867
rs988748

SZGene Recent Updates
SZGene Stats
Studies: 1727
Genes: 1008
Polymorphisms: 8788
Meta-analyses: 287
ALSGene
AlzGene
MSGene
PDGene
SZGene
An up-to-date collection of all published genetic association studies.
SRF News
SRF Comments
Text Size
Reset Text Size
Email this pageEmail this page

Share/Bookmark
Research Participants
Collaborators
Copyright © 2005-2024 Schizophrenia Research Forum Privacy Policy Disclaimer Disclosure Copyright