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Meta-Analysis of All Published SZ Association Studies (Case-Control Only) rs6691840
Back Search Methods Disclaimer Credits
 Polymorphism: rs6691840 (Ser310Ala)
 Gene: GRIK3  (EAA5; GLR7; GLUR7; GluR7a)  Entrez Gene    View on MSGene
 Protein: glutamate receptor 7  (excitatory amino acid receptor 5)  ProteinLink
 Chromosome: 1   (View: 1  2  3  4  5  6  7  8  9  10  11  12  13  14  15  16  17  18  19  20  21  22  X  Y  MT)
 Status: Updated 22 October 2010
Gene Overview
 Polymorphism:
1) Summary of Allele and Genotype Distribution of all Published Association Studies (by Ethnic Group)
      Alleles Genotypes
  # Case-Control
Samples
  G-Allele
(frequency)
T-Allele
(frequency)
G/G
(frequency)
G/T
(frequency)
T/T
(frequency)
 Caucasian 3 SZ
CTR
0.28
0.26
0.72
0.75
48 (0.089)
34 (0.063)
211 (0.391)
208 (0.384)
281 (0.520)
300 (0.554)
 Asian 1 SZ
CTR
0.07
0.06
0.93
0.94
1 (0.006)
0 (0.000)
19 (0.119)
18 (0.113)
140 (0.875)
142 (0.888)
 Other/Mixed 1 SZ
CTR
0.44
0.32
0.56
0.69
9 (0.090)
15 (0.150)
70 (0.700)
33 (0.330)
21 (0.210)
52 (0.520)
Total 5 SZ
CTR
0.26
0.22
0.74
0.78
58 (0.073)
49 (0.061)
300 (0.375)
259 (0.323)
442 (0.553)
494 (0.616)

Meta-Analysis Methods      * New * Cumulative Meta-analysis
2) Forest plot for polymorphism  rs6691840 (Ser310Ala)

Please also see disclaimer for more information on these meta-analyses.


Meta-analyses have not been performed on the following polymorphisms since they lack published genotype data in at least four independent case-control samples, or the published genotype data was otherwise not eligible for inclusion (see methods for details):

rs12067006
rs12132499
rs12133182
rs1587526
rs16823687
rs17461259
rs1762067
rs2993076
rs3753771
rs3753776
rs3767042
rs3767045
rs3767048
rs3767067
rs3767080
rs3767081
rs3767086
rs3767092
rs3767100
rs3820274
rs4652931
rs472188
rs478273
rs481047
rs493243
rs494070
rs507460
rs532383
rs534131
rs535620
rs539308
rs550250
rs551794
rs554445
rs565537
rs575605
rs6656317
rs6671364
rs7517274
rs822856
rs904896

SZGene Recent Updates
SZGene Stats
Studies: 1727
Genes: 1008
Polymorphisms: 8788
Meta-analyses: 287
ALSGene
AlzGene
MSGene
PDGene
SZGene
An up-to-date collection of all published genetic association studies.
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