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Meta-Analysis of All Published SZ Association Studies (Case-Control Only) rs6311
Back Search Methods Disclaimer Credits
 Polymorphism: rs6311 (-1438A/G)
 Gene: HTR2A  (HTR2; 5-HT2A)  Entrez Gene    View on AlzGene   View on PDGene
 Protein: 5-hydroxytryptamine receptor 2A  (5-HT2 receptor; serotonin receptor 2A)  ProteinLink
 Chromosome: 13   (View: 1  2  3  4  5  6  7  8  9  10  11  12  13  14  15  16  17  18  19  20  21  22  X  Y  MT)
 Status: Updated 22 October 2010
Gene Overview
 Polymorphism:
1) Summary of Allele and Genotype Distribution of all Published Association Studies (by Ethnic Group)
      Alleles Genotypes
  # Case-Control
Samples		   A-Allele
(frequency)		 G-Allele
(frequency)		 A/A
(frequency)		 A/G
(frequency)		 G/G
(frequency)
 Caucasian 7 SZ
CTR		 0.44
0.41		 0.56
0.59		 511 (0.197)
484 (0.169)		 1282 (0.494)
1393 (0.486)		 801 (0.309)
992 (0.346)
 Asian 2 SZ
CTR		 0.41
0.44		 0.59
0.56		 156 (0.182)
191 (0.210)		 384 (0.448)
416 (0.458)		 317 (0.370)
301 (0.331)
 Other/Mixed 3 SZ
CTR		 0.51
0.60		 0.49
0.40		 142 (0.304)
113 (0.401)		 193 (0.413)
114 (0.404)		 132 (0.283)
55 (0.195)
Total 12 SZ
CTR		 0.44
0.43		 0.56
0.57		 809 (0.206)
788 (0.194)		 1859 (0.474)
1923 (0.474)		 1250 (0.319)
1348 (0.332)

Meta-Analysis Methods      * New * Cumulative Meta-analysis
2) Forest plot for polymorphism  rs6311 (-1438A/G)

Please also see disclaimer for more information on these meta-analyses.

Meta-analyses have not been performed on the following polymorphisms since they lack published genotype data in at least four independent case-control samples, or the published genotype data was otherwise not eligible for inclusion (see methods for details):

HTR2A_C516T
rs10507544
rs10507546
rs1328684
rs1328685
rs1360020
rs17289304
rs1805055 (Thr25Asn)
rs1923882
rs1923884
rs1923886
rs1928040
rs1928042
rs2070036
rs2070037
rs2070040
rs2149434
rs2296972
rs2770296
rs3125
rs3742278
rs3889066
rs4941573
rs582385
rs6305
rs6310
rs6312
rs643627
rs6561333
rs659734
rs677702
rs731244
rs731779
rs7323441
rs7324218
rs7325168
rs7333412
rs7997012
rs912127
rs927544
rs9316233
rs9316235
rs9534505
rs9534511
rs977003
rs985933
rs985934

SZGene Recent Updates
SZGene Stats
Studies: 1727
Genes: 1008
Polymorphisms: 8788
Meta-analyses: 287
ALSGene
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MSGene
PDGene
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An up-to-date collection of all published genetic association studies.
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