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Meta-Analysis of All Published SZ Association Studies (Case-Control Only) rs1801133
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 Polymorphism: rs1801133 (677T/C)
 Gene: MTHFR   Entrez Gene    View on ALSGene   View on AlzGene   View on MSGene   View on PDGene
 Protein: 5,10-methylenetetrahydrofolate reductase (NADPH)  (methylenetetrahydrofolate reductase)  ProteinLink
 Chromosome: 1   (View: 1  2  3  4  5  6  7  8  9  10  11  12  13  14  15  16  17  18  19  20  21  22  X  Y  MT)
 Status: Updated 22 October 2010
Gene Overview
 Polymorphism:
1) Summary of Allele and Genotype Distribution of all Published Association Studies (by Ethnic Group)
      Alleles Genotypes
  # Case-Control
Samples
  T-Allele
(frequency)
C-Allele
(frequency)
T/T
(frequency)
T/C
(frequency)
C/C
(frequency)
 Caucasian 12 SZ
CTR
0.32
0.30
0.68
0.70
305 (0.112)
417 (0.098)
1143 (0.421)
1729 (0.407)
1266 (0.466)
2106 (0.495)
 Asian 6 SZ
CTR
0.40
0.36
0.60
0.64
248 (0.169)
171 (0.122)
681 (0.465)
682 (0.485)
535 (0.365)
553 (0.393)
 Hispanic 1 SZ
CTR
0.51
0.54
0.49
0.46
31 (0.295)
31 (0.290)
45 (0.429)
54 (0.505)
29 (0.276)
22 (0.206)
 Other/Mixed 1 SZ
CTR
0.28
0.32
0.72
0.68
6 (0.076)
8 (0.107)
32 (0.405)
32 (0.427)
41 (0.519)
35 (0.467)
Total 20 SZ
CTR
0.35
0.32
0.65
0.68
590 (0.135)
627 (0.107)
1901 (0.436)
2497 (0.428)
1871 (0.429)
2716 (0.465)

Meta-Analysis Methods      * New * Cumulative Meta-analysis
2) Forest plot for polymorphism  rs1801133 (677T/C)

Please also see disclaimer for more information on these meta-analyses.

SZGene Recent Updates
SZGene Stats
Studies: 1727
Genes: 1008
Polymorphisms: 8788
Meta-analyses: 287
ALSGene
AlzGene
MSGene
PDGene
SZGene
An up-to-date collection of all published genetic association studies.
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