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, the Brain and Behavior Research Fund, and was created with funding from the
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Printable version
Meta-Analysis of All Published SZ Association Studies (Case-Control Only)
rs1800629
Polymorphism:
rs1800629 (308A/G)
Gene:
TNF
(DIF; TNFA; TNFSF2; TNF-alpha)
View on ALSGene
View on AlzGene
View on MSGene
View on PDGene
Protein:
tumor necrosis factor alpha
(cachectin; APC1 protein)
Chromosome:
6
(View:
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
X
Y
MT
)
Status:
Updated 22 October 2010
Polymorphism:
rs1799724
rs1800629
rs361525
1) Summary of Allele and Genotype Distribution of all Published Association Studies (by Ethnic Group)
Alleles
Genotypes
# Case-Control
Samples
A-Allele
(frequency)
G-Allele
(frequency)
A/A
(frequency)
A/G
(frequency)
G/G
(frequency)
Caucasian
8
SZ
CTR
0.13
0.14
0.87
0.86
29 (0.022)
31 (0.019)
287 (0.221)
393 (0.241)
985 (0.757)
1208 (0.740)
Asian
7
SZ
CTR
0.07
0.06
0.93
0.94
11 (0.006)
12 (0.007)
214 (0.120)
189 (0.103)
1551 (0.873)
1642 (0.891)
Other/Mixed
1
SZ
CTR
0.16
0.11
0.84
0.89
8 (0.043)
5 (0.008)
44 (0.237)
140 (0.213)
134 (0.720)
512 (0.779)
Total
16
SZ
CTR
0.10
0.10
0.90
0.90
48 (0.015)
48 (0.012)
545 (0.167)
722 (0.175)
2670 (0.818)
3362 (0.814)
Meta-Analysis Methods
* New *
Cumulative Meta-analysis
2) Forest plot for polymorphism
rs1800629 (308A/G)
Please also
see disclaimer
for more information on these meta-analyses.
Meta-analyses have not been performed on the following polymorphisms since they lack published genotype data in at least four independent case-control samples, or the published genotype data was otherwise not eligible for inclusion (see
methods
for details):
rs1799724 (T857C)
rs1799964
rs1800610
rs1800630
rs1800750 (376G/A)
rs2844482
rs3093543
rs3093664
rs4647198 (C1031T)
TNF_863C/A
SZGene Recent Updates
SZGene Stats
Studies: 1727
Genes: 1008
Polymorphisms: 8788
Meta-analyses: 287
ALSGene
AlzGene
MSGene
PDGene
SZGene
An up-to-date collection of all published genetic association studies.
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