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Meta-Analysis of All Published SZ Association Studies (Case-Control Only) rs3803300
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 Polymorphism: rs3803300 (SNP1)
 Gene: AKT1  (PKB; PRKBA; RAC; RAC-ALPHA)  Entrez Gene    View on PDGene
 Protein: v-akt murine thymoma viral oncogene homolog 1  (protein kinase B; rac protein kinase alpha; RAC-alpha serine/threonine-protein kinase)  ProteinLink
 Chromosome: 14   (View: 1  2  3  4  5  6  7  8  9  10  11  12  13  14  15  16  17  18  19  20  21  22  X  Y  MT)
 Status: Updated 21 October 2010
Gene Overview
 Polymorphism:
1) Summary of Allele and Genotype Distribution of all Published Association Studies (by Ethnic Group)
      Alleles Genotypes
  # Case-Control
Samples		   A-Allele
(frequency)		 G-Allele
(frequency)		 A/A
(frequency)		 A/G
(frequency)		 G/G
(frequency)
 Caucasian 4 SZ
CTR		 0.11
0.10		 0.89
0.90		 22 (0.017)
17 (0.012)		 234 (0.180)
262 (0.184)		 1045 (0.803)
1145 (0.804)
 Asian 4 SZ
CTR		 0.58
0.59		 0.42
0.41		 571 (0.339)
612 (0.359)		 803 (0.477)
805 (0.472)		 311 (0.185)
290 (0.170)
 Other/Mixed 1 SZ
CTR		 0.22
0.20		 0.78
0.80		 16 (0.050)
15 (0.039)		 111 (0.345)
123 (0.321)		 195 (0.606)
245 (0.640)
Total 9 SZ
CTR		 0.36
0.35		 0.64
0.65		 609 (0.184)
644 (0.183)		 1148 (0.347)
1190 (0.339)		 1551 (0.469)
1680 (0.478)

Meta-Analysis Methods      * New * Cumulative Meta-analysis
2) Forest plot for polymorphism  rs3803300 (SNP1)

Please also see disclaimer for more information on these meta-analyses.

Meta-analyses have not been performed on the following polymorphisms since they lack published genotype data in at least four independent case-control samples, or the published genotype data was otherwise not eligible for inclusion (see methods for details):

D14S260
rs10149779
rs11847866
rs2494731
rs2494734
rs2494738
rs2494743
rs2494746
rs2494747
rs2494750
rs2494752
rs2498784
rs2498794
rs2498796
rs2498802
rs3001371
rs3730344
rs3803304
rs8192700

SZGene Recent Updates
SZGene Stats
Studies: 1727
Genes: 1008
Polymorphisms: 8788
Meta-analyses: 287
ALSGene
AlzGene
MSGene
PDGene
SZGene
An up-to-date collection of all published genetic association studies.
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