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Meta-Analysis of All Published SZ Association Studies (Case-Control Only) rs1800955
Back Search Methods Disclaimer Credits
 Polymorphism: rs1800955 (521T/C)
 Gene: DRD4  (D4DR)  Entrez Gene    View on AlzGene   View on PDGene
 Protein: dopamine receptor D4  (D(2C) dopamine receptor; seven transmembrane helix receptor)  ProteinLink
 Chromosome: 11   (View: 1  2  3  4  5  6  7  8  9  10  11  12  13  14  15  16  17  18  19  20  21  22  X  Y  MT)
 Status: Updated 21 October 2010
Gene Overview
 Polymorphism:
1) Summary of Allele and Genotype Distribution of all Published Association Studies (by Ethnic Group)
      Alleles Genotypes
  # Case-Control
Samples
  C-Allele
(frequency)
T-Allele
(frequency)
C/C
(frequency)
C/T
(frequency)
T/T
(frequency)
 Caucasian 2 SZ
CTR
0.44
0.44
0.56
0.56
44 (0.171)
85 (0.171)
140 (0.543)
264 (0.530)
74 (0.287)
149 (0.299)
 Asian 6 SZ
CTR
0.42
0.39
0.58
0.61
403 (0.184)
314 (0.156)
1041 (0.475)
952 (0.474)
748 (0.341)
742 (0.370)
Total 8 SZ
CTR
0.42
0.40
0.58
0.60
447 (0.182)
399 (0.159)
1181 (0.482)
1216 (0.485)
822 (0.336)
891 (0.356)

Meta-Analysis Methods      * New * Cumulative Meta-analysis
2) Forest plot for polymorphism  rs1800955 (521T/C)

Please also see disclaimer for more information on these meta-analyses.


Meta-analyses have not been performed on the following polymorphisms since they lack published genotype data in at least four independent case-control samples, or the published genotype data was otherwise not eligible for inclusion (see methods for details):

DRD4_11C/T
DRD4_48bpVNTR (exon3)
DRD4_Gly11Arg
DRD4_HincII
DRD4_PstI
DRD4_SmaI
rs10902180 (600G/C)
rs11246224 (713C/T)
rs11246226
rs12720364 (1217G/del)
rs1800443 (Val194Gly)
rs2396543 (602G/del)
rs3758653 (906T/C)
rs3842250 (597G2-5)
rs41298422 (930C/G/T)
rs4331145
rs4646983 (13bp-indel)
rs4987058 (768G/A)
rs71695878 (G-repeat)
rs71695878 (G-repeat)
rs747303 (603del/T)
rs916455 (376C/T)
rs916457 (291C/T)
rs936460 (1106T/C)
rs936461 (809G/A)
rs936465

SZGene Recent Updates
SZGene Stats
Studies: 1727
Genes: 1008
Polymorphisms: 8788
Meta-analyses: 287
ALSGene
AlzGene
MSGene
PDGene
SZGene
An up-to-date collection of all published genetic association studies.
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