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, the Brain and Behavior Research Fund, and was created with funding from the
U.S. National Institute of Mental Health
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Printable version
Polymorphism Details
Study:
Iwata, 2006
Gene:
CHRNA7
(NACHRA7)
View on AlzGene
View on PDGene
Protein:
cholinergic receptor, nicotinic, alpha 7
(alpha7 nicotinic receptor subunit; a7 nicotinic acetylcholine receptor; nicotinic cholinergic receptor alpha 7; nicotinic acetylcholine alpha-7 subunit; alpha-7 nicotinic cholinergic receptor subunit; alpha 7 neuronal nicotinic acetylcholine receptor; cholinergic receptor, nicotinic, alpha polypeptide 7; neuronal nicotinic acetylcholine receptor alpha-7 subunit; nicotinic acetylcholine receptor alpha7 subunit precursor)
Chromosome:
15
(View:
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
X
Y
MT
)
Status:
Updated 21 October 2010
Total number of polymorphisms investigated by this study: 9
Case-Control Studies (by ethnic group)
Genotypes
Polymorphism ID#
(Link to NCBI)
Population
n.a.-Allele
n.a.-Allele
n.a./n.a.
(frequency)
n.a./n.a.
(frequency)
n.a./n.a.
(frequency)
Asian
D15S1360
China
SZ
CTR
-
-
-
-
0 (-)
0 (-)
0 (-)
0 (-)
0 (-)
0 (-)
(-)
: Either no data provided, or data otherwise not eligible for inclusion (
see methods for details)
.
Case-Control Studies (by ethnic group)
Genotypes
Polymorphism ID#
(Link to NCBI)
Population
C-Allele
A-Allele
C/C
(frequency)
C/A
(frequency)
A/A
(frequency)
Asian
rs1514246
China
SZ
CTR
0.21
0.21
0.79
0.79
8 (0.043)
6 (0.032)
62 (0.330)
68 (0.360)
118 (0.628)
115 (0.608)
Case-Control Studies (by ethnic group)
Genotypes
Polymorphism ID#
(Link to NCBI)
Population
C-Allele
T-Allele
C/C
(frequency)
C/T
(frequency)
T/T
(frequency)
Asian
rs3826029
China
SZ
CTR
0.42
0.41
0.58
0.59
30 (0.160)
30 (0.160)
98 (0.521)
96 (0.511)
60 (0.319)
62 (0.330)
Case-Control Studies (by ethnic group)
Genotypes
Polymorphism ID#
(Link to NCBI)
Population
T-Allele
C-Allele
T/T
(frequency)
T/C
(frequency)
C/C
(frequency)
Asian
rs868437
China
SZ
CTR
0.21
0.20
0.79
0.80
8 (0.043)
6 (0.032)
62 (0.330)
62 (0.333)
118 (0.628)
118 (0.634)
Case-Control Studies (by ethnic group)
Genotypes
Polymorphism ID#
(Link to NCBI)
Population
G-Allele
A-Allele
G/G
(frequency)
G/A
(frequency)
A/A
(frequency)
Asian
rs2337506
China
SZ
CTR
0.29
0.28
0.71
0.72
13 (0.069)
13 (0.070)
83 (0.441)
77 (0.414)
92 (0.489)
96 (0.516)
Case-Control Studies (by ethnic group)
Genotypes
Polymorphism ID#
(Link to NCBI)
Population
G-Allele
C-Allele
G/G
(frequency)
G/C
(frequency)
C/C
(frequency)
Asian
rs982574
China
SZ
CTR
0.22
0.22
0.78
0.78
9 (0.048)
8 (0.042)
64 (0.344)
68 (0.360)
113 (0.608)
113 (0.598)
Case-Control Studies (by ethnic group)
Genotypes
Polymorphism ID#
(Link to NCBI)
Population
C-Allele
T-Allele
C/C
(frequency)
C/T
(frequency)
T/T
(frequency)
Asian
rs904952
China
SZ
CTR
0.27
0.30
0.73
0.70
13 (0.069)
21 (0.112)
77 (0.410)
71 (0.378)
98 (0.521)
96 (0.511)
Case-Control Studies (by ethnic group)
Genotypes
Polymorphism ID#
(Link to NCBI)
Population
T-Allele
C-Allele
T/T
(frequency)
T/C
(frequency)
C/C
(frequency)
Asian
rs2337980
China
SZ
CTR
0.31
0.26
0.69
0.74
9 (0.048)
11 (0.059)
96 (0.516)
75 (0.403)
81 (0.435)
100 (0.538)
Case-Control Studies (by ethnic group)
Genotypes
Polymorphism ID#
(Link to NCBI)
Population
G-Allele
A-Allele
G/G
(frequency)
G/A
(frequency)
A/A
(frequency)
Asian
rs3935407
China
SZ
CTR
0.10
0.08
0.90
0.92
2 (0.011)
2 (0.011)
34 (0.181)
24 (0.129)
152 (0.809)
160 (0.860)
SZGene Recent Updates
SZGene Stats
Studies: 1727
Genes: 1008
Polymorphisms: 8788
Meta-analyses: 287
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