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Polymorphism Details     
Back Search Methods Disclaimer Credits
 Study: Gilks, 2009
 Gene: HOMER2  (CPD; ACPD; Vesl-2; HOMER2A; HOMER2B)  Entrez Gene
 Protein: homer 2  (cupidin; homer homolog 3 (Drosophila); homer, neuronal immediate early gene, 2)  ProteinLink
 Chromosome: 15   (View: 1  2  3  4  5  6  7  8  9  10  11  12  13  14  15  16  17  18  19  20  21  22  X  Y  MT)
 Status: Updated 19 January 2010
Meta-Analysis     Gene Overview
Total number of polymorphisms investigated by this study: 28

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   A-Allele G-Allele A/A
(frequency)		 A/G
(frequency)		 G/G
(frequency)
 Caucasian
rs1256430 Ireland (I) SZ
CTR		 0.16
0.16		 0.84
0.84		 11 (0.027)
21 (0.026)		 110 (0.274)
220 (0.271)		 280 (0.698)
571 (0.703)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   T-Allele C-Allele T/T
(frequency)		 T/C
(frequency)		 C/C
(frequency)
 Caucasian
rs12442119 Ireland (I) SZ
CTR		 0.27
0.27		 0.73
0.73		 29 (0.072)
60 (0.074)		 158 (0.394)
322 (0.397)		 214 (0.534)
430 (0.530)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   G-Allele C-Allele G/G
(frequency)		 G/C
(frequency)		 C/C
(frequency)
 Caucasian
rs1256426 Ireland (I) SZ
CTR		 0.47
0.45		 0.53
0.55		 90 (0.224)
167 (0.206)		 200 (0.499)
403 (0.496)		 111 (0.277)
242 (0.298)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   T-Allele C-Allele T/T
(frequency)		 T/C
(frequency)		 C/C
(frequency)
 Caucasian
rs2306428 Ireland (I) SZ
CTR		 0.05
0.08		 0.95
0.92		 1 (0.002)
6 (0.007)		 41 (0.102)
126 (0.155)		 359 (0.895)
680 (0.837)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   C-Allele T-Allele C/C
(frequency)		 C/T
(frequency)		 T/T
(frequency)
 Caucasian
rs1256444 Ireland (I) SZ
CTR		 0.46
0.44		 0.54
0.56		 86 (0.214)
159 (0.196)		 199 (0.496)
401 (0.494)		 116 (0.289)
252 (0.310)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   T-Allele C-Allele T/T
(frequency)		 T/C
(frequency)		 C/C
(frequency)
 Caucasian
rs1256455 Ireland (I) SZ
CTR		 0.25
0.23		 0.75
0.77		 25 (0.062)
41 (0.050)		 151 (0.377)
284 (0.350)		 225 (0.561)
487 (0.600)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   A-Allele G-Allele A/A
(frequency)		 A/G
(frequency)		 G/G
(frequency)
 Caucasian
rs2621226 Ireland (I) SZ
CTR		 0.44
0.43		 0.56
0.57		 78 (0.195)
149 (0.183)		 198 (0.494)
398 (0.490)		 125 (0.312)
265 (0.326)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   C-Allele T-Allele C/C
(frequency)		 C/T
(frequency)		 T/T
(frequency)
 Caucasian
rs17359494 Ireland (I) SZ
CTR		 0.22
0.24		 0.78
0.76		 20 (0.050)
48 (0.059)		 139 (0.347)
299 (0.368)		 242 (0.603)
465 (0.573)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   A-Allele G-Allele A/A
(frequency)		 A/G
(frequency)		 G/G
(frequency)
 Caucasian
rs2621227 Ireland (I) SZ
CTR		 0.49
0.50		 0.51
0.50		 97 (0.242)
201 (0.248)		 201 (0.501)
406 (0.500)		 103 (0.257)
205 (0.252)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   A-Allele T-Allele A/A
(frequency)		 A/T
(frequency)		 T/T
(frequency)
 Caucasian
SNP36 (exon2) Ireland (I) SZ
CTR		 0.01
0.01		 0.99
0.99		 0 (0.000)
0 (0.000)		 8 (0.020)
22 (0.027)		 393 (0.980)
790 (0.973)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   C-Allele T-Allele C/C
(frequency)		 C/T
(frequency)		 T/T
(frequency)
 Caucasian
rs7174726 Ireland (I) SZ
CTR		 0.07
0.09		 0.93
0.91		 2 (0.005)
7 (0.009)		 49 (0.122)
140 (0.172)		 350 (0.873)
665 (0.819)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   C-Allele A-Allele C/C
(frequency)		 C/A
(frequency)		 A/A
(frequency)
 Caucasian
rs7496832 Ireland (I) SZ
CTR		 0.11
0.14		 0.89
0.86		 5 (0.012)
15 (0.018)		 78 (0.195)
193 (0.238)		 318 (0.793)
604 (0.744)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   A-Allele T-Allele A/A
(frequency)		 A/T
(frequency)		 T/T
(frequency)
 Caucasian
SNP19 Ireland (I) SZ
CTR		 0.02
0.02		 0.98
0.98		 0 (0.000)
0 (0.000)		 20 (0.050)
27 (0.033)		 381 (0.950)
785 (0.967)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   T-Allele C-Allele T/T
(frequency)		 T/C
(frequency)		 C/C
(frequency)
 Caucasian
SNP20 Ireland (I) SZ
CTR		 0.11
0.14		 0.89
0.86		 5 (0.012)
16 (0.020)		 80 (0.200)
198 (0.244)		 316 (0.788)
598 (0.736)
SNP20 Ireland (II) SZ
CTR		 0.14
0.13		 0.86
0.87		 8 (0.020)
14 (0.017)		 101 (0.248)
186 (0.221)		 299 (0.733)
640 (0.762)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   T-Allele C-Allele T/T
(frequency)		 T/C
(frequency)		 C/C
(frequency)
 Caucasian
rs12913501 Ireland (I) SZ
CTR		 0.11
0.14		 0.89
0.86		 5 (0.012)
17 (0.021)		 78 (0.195)
199 (0.245)		 318 (0.793)
596 (0.734)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   T-Allele C-Allele T/T
(frequency)		 T/C
(frequency)		 C/C
(frequency)
 Caucasian
rs869498 Ireland (I) SZ
CTR		 0.13
0.10		 0.87
0.90		 7 (0.017)
8 (0.010)		 92 (0.229)
146 (0.180)		 302 (0.753)
658 (0.810)
rs869498 Ireland (II) SZ
CTR		 0.11
0.12		 0.89
0.88		 5 (0.012)
12 (0.014)		 82 (0.201)
177 (0.211)		 321 (0.787)
650 (0.775)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   G-Allele A-Allele G/G
(frequency)		 G/A
(frequency)		 A/A
(frequency)
 Caucasian
rs12148275 Ireland (I) SZ
CTR		 0.49
0.48		 0.51
0.52		 95 (0.237)
190 (0.234)		 200 (0.499)
406 (0.500)		 106 (0.264)
216 (0.266)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   A-Allele T-Allele A/A
(frequency)		 A/T
(frequency)		 T/T
(frequency)
 Caucasian
rs12050725 Ireland (I) SZ
CTR		 0.20
0.19		 0.80
0.81		 16 (0.040)
28 (0.034)		 129 (0.322)
246 (0.303)		 256 (0.638)
538 (0.663)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   A-Allele G-Allele A/A
(frequency)		 A/G
(frequency)		 G/G
(frequency)
 Caucasian
rs12443081 Ireland (I) SZ
CTR		 0.10
0.10		 0.90
0.90		 4 (0.010)
8 (0.010)		 73 (0.182)
145 (0.179)		 324 (0.808)
659 (0.812)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   T-Allele C-Allele T/T
(frequency)		 T/C
(frequency)		 C/C
(frequency)
 Caucasian
rs2061947 Ireland (I) SZ
CTR		 0.47
0.45		 0.53
0.55		 87 (0.217)
163 (0.201)		 200 (0.499)
402 (0.495)		 114 (0.284)
247 (0.304)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   T-Allele C-Allele T/T
(frequency)		 T/C
(frequency)		 C/C
(frequency)
 Caucasian
rs7170046 Ireland (I) SZ
CTR		 0.10
0.11		 0.90
0.89		 4 (0.010)
10 (0.012)		 73 (0.182)
163 (0.201)		 324 (0.808)
639 (0.787)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   A-Allele T-Allele A/A
(frequency)		 A/T
(frequency)		 T/T
(frequency)
 Caucasian
rs1010820 Ireland (I) SZ
CTR		 0.19
0.22		 0.81
0.78		 15 (0.037)
39 (0.048)		 125 (0.312)
278 (0.342)		 261 (0.651)
495 (0.610)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   G-Allele A-Allele G/G
(frequency)		 G/A
(frequency)		 A/A
(frequency)
 Caucasian
rs11857990 Ireland (I) SZ
CTR		 0.30
0.33		 0.70
0.67		 35 (0.087)
87 (0.107)		 167 (0.416)
358 (0.441)		 199 (0.496)
367 (0.452)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   A-Allele T-Allele A/A
(frequency)		 A/T
(frequency)		 T/T
(frequency)
 Caucasian
rs4842928 Ireland (I) SZ
CTR		 0.17
0.17		 0.83
0.83		 12 (0.030)
23 (0.028)		 114 (0.284)
229 (0.282)		 275 (0.686)
560 (0.690)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   G-Allele C-Allele G/G
(frequency)		 G/C
(frequency)		 C/C
(frequency)
 Caucasian
rs1871658 Ireland (I) SZ
CTR		 0.43
0.40		 0.57
0.60		 75 (0.187)
127 (0.156)		 197 (0.491)
389 (0.479)		 129 (0.322)
296 (0.365)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   T-Allele C-Allele T/T
(frequency)		 T/C
(frequency)		 C/C
(frequency)
 Caucasian
rs6603038 Ireland (I) SZ
CTR		 0.51
0.48		 0.49
0.52		 104 (0.259)
186 (0.229)		 201 (0.501)
405 (0.499)		 96 (0.239)
221 (0.272)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   T-Allele C-Allele T/T
(frequency)		 T/C
(frequency)		 C/C
(frequency)
 Caucasian
rs2304628 Ireland (II) SZ
CTR		 0.08
0.09		 0.92
0.91		 2 (0.005)
7 (0.008)		 59 (0.145)
138 (0.164)		 347 (0.850)
695 (0.827)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   m-Allele M-Allele m/m
(frequency)		 m/M
(frequency)		 M/M
(frequency)
 Caucasian
HOMER2_SNPunknown (proxy to rs2304628) Sweden, Bulgaria, UK (ISC GWAS) SZ
CTR		 0.11
0.12		 0.89
0.88		 16 (0.012)
16 (0.014)		 258 (0.200)
238 (0.211)		 1013 (0.787)
874 (0.775)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.
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Genes: 1008
Polymorphisms: 8788
Meta-analyses: 287
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