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Printable version  
Polymorphism Details     
Back Search Methods Disclaimer Credits
 Study: Thomson, 2005
 Gene: DISC1  (SCZD9)  Entrez Gene
 Protein: disrupted in schizophrenia 1   ProteinLink
 Chromosome: 1   (View: 1  2  3  4  5  6  7  8  9  10  11  12  13  14  15  16  17  18  19  20  21  22  X  Y  MT)
 Status: Updated 21 October 2010
Meta-Analysis     Gene Overview
Total number of polymorphisms investigated by this study: 26

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)
Population   A-Allele G-Allele A/A
(frequency)
A/G
(frequency)
G/G
(frequency)
 Caucasian
rs999710 (hCV9628231) UK (Scotland) SZ
CTR
0.40
0.38
0.60
0.62
63 (0.160)
69 (0.144)
189 (0.480)
225 (0.471)
142 (0.360)
184 (0.385)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)
Population   A-Allele T-Allele A/A
(frequency)
A/T
(frequency)
T/T
(frequency)
 Caucasian
rs821616 (hCV1433135; T2163A) UK (Scotland) SZ
CTR
0.28
0.29
0.72
0.71
31 (0.079)
40 (0.084)
159 (0.404)
197 (0.412)
204 (0.518)
241 (0.504)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)
Population   T-Allele C-Allele T/T
(frequency)
T/C
(frequency)
C/C
(frequency)
 Caucasian
rs821597 (hCV1433188) UK (Scotland) SZ
CTR
0.34
0.37
0.66
0.63
46 (0.116)
65 (0.136)
177 (0.448)
223 (0.467)
172 (0.435)
190 (0.397)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)
Population   T-Allele C-Allele T/T
(frequency)
T/C
(frequency)
C/C
(frequency)
 Caucasian
rs734551 (hCV1650709) UK (Scotland) SZ
CTR
0.43
0.43
0.57
0.57
73 (0.185)
89 (0.186)
193 (0.490)
234 (0.490)
128 (0.325)
155 (0.324)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)
Population   G-Allele C-Allele G/G
(frequency)
G/C
(frequency)
C/C
(frequency)
 Caucasian
rs2812393 (hCV16113570) UK (Scotland) SZ
CTR
-
-
-
-
0 (-)
0 (-)
0 (-)
0 (-)
0 (-)
0 (-)
(-) :  Either no data provided, or data otherwise not eligible for inclusion (see methods for details).

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)
Population   T-Allele C-Allele T/T
(frequency)
T/C
(frequency)
C/C
(frequency)
 Caucasian
rs2038636 (hCV1650750) UK (Scotland) SZ
CTR
0.41
0.40
0.59
0.60
66 (0.168)
77 (0.161)
191 (0.485)
229 (0.479)
137 (0.348)
172 (0.360)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)
Population   G-Allele A-Allele G/G
(frequency)
G/A
(frequency)
A/A
(frequency)
 Caucasian
rs1954175 (hCV12001940) UK (Scotland) SZ
CTR
0.34
0.38
0.66
0.62
45 (0.114)
69 (0.144)
177 (0.449)
225 (0.471)
172 (0.437)
184 (0.385)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)
Population   T-Allele A-Allele T/T
(frequency)
T/A
(frequency)
A/A
(frequency)
 Caucasian
rs1030711 UK (Scotland) SZ
CTR
0.33
0.33
0.67
0.67
43 (0.109)
52 (0.109)
174 (0.442)
211 (0.441)
177 (0.449)
215 (0.450)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)
Population   A-Allele G-Allele A/A
(frequency)
A/G
(frequency)
G/G
(frequency)
 Caucasian
rs1000730 UK (Scotland) SZ
CTR
0.38
0.39
0.62
0.61
57 (0.145)
73 (0.153)
186 (0.472)
227 (0.475)
151 (0.383)
178 (0.372)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)
Population   A-Allele G-Allele A/A
(frequency)
A/G
(frequency)
G/G
(frequency)
 Caucasian
rs821663 UK (Scotland) SZ
CTR
0.31
0.35
0.69
0.65
38 (0.096)
59 (0.123)
168 (0.426)
217 (0.454)
188 (0.477)
202 (0.423)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)
Population   A-Allele G-Allele A/A
(frequency)
A/G
(frequency)
G/G
(frequency)
 Caucasian
rs3738401 (hCV25641899; A844G) UK (Scotland) SZ
CTR
0.33
0.36
0.67
0.64
43 (0.109)
62 (0.130)
174 (0.442)
220 (0.460)
177 (0.449)
196 (0.410)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)
Population   T-Allele C-Allele T/T
(frequency)
T/C
(frequency)
C/C
(frequency)
 Caucasian
rs1000731 (hCV1650688) UK (Scotland) SZ
CTR
0.22
0.22
0.78
0.78
19 (0.048)
23 (0.048)
135 (0.343)
164 (0.343)
240 (0.609)
291 (0.609)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)
Population   C-Allele T-Allele C/C
(frequency)
C/T
(frequency)
T/T
(frequency)
 Caucasian
rs751229 UK (Scotland) SZ
CTR
0.38
0.41
0.62
0.59
57 (0.145)
80 (0.168)
186 (0.472)
231 (0.484)
151 (0.383)
166 (0.348)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)
Population   T-Allele C-Allele T/T
(frequency)
T/C
(frequency)
C/C
(frequency)
 Caucasian
rs6675281 (hCV1650667; C1872T) UK (Scotland) SZ
CTR
0.14
0.14
0.86
0.86
8 (0.020)
9 (0.019)
95 (0.241)
115 (0.241)
291 (0.739)
354 (0.741)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)
Population   m-Allele M-Allele m/m
(frequency)
m/M
(frequency)
M/M
(frequency)
 Caucasian
rs1984895 (rs3890280) UK (Scotland) SZ
CTR
0.23
0.22
0.77
0.78
21 (0.053)
23 (0.048)
139 (0.353)
164 (0.343)
234 (0.594)
291 (0.609)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)
Population   A-Allele G-Allele A/A
(frequency)
A/G
(frequency)
G/G
(frequency)
 Caucasian
rs1411776 (hCV9626960) UK (Scotland) SZ
CTR
0.15
0.16
0.85
0.84
9 (0.023)
12 (0.025)
100 (0.254)
129 (0.270)
285 (0.723)
337 (0.705)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)
Population   C-Allele T-Allele C/C
(frequency)
C/T
(frequency)
T/T
(frequency)
 Caucasian
rs1411771 UK (Scotland) SZ
CTR
0.29
0.30
0.71
0.70
33 (0.084)
43 (0.090)
162 (0.411)
201 (0.421)
199 (0.505)
234 (0.490)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)
Population   T-Allele A-Allele T/T
(frequency)
T/A
(frequency)
A/A
(frequency)
 Caucasian
rs1160491 UK (Scotland) SZ
CTR
0.33
0.37
0.67
0.63
43 (0.109)
65 (0.136)
174 (0.442)
223 (0.467)
177 (0.449)
190 (0.397)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)
Population   T-Allele C-Allele T/T
(frequency)
T/C
(frequency)
C/C
(frequency)
 Caucasian
rs2492367 (C1460T) UK (Scotland) SZ
CTR
0.13
0.12
0.87
0.88
7 (0.018)
7 (0.015)
89 (0.226)
101 (0.211)
298 (0.756)
370 (0.774)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)
Population   C-Allele T-Allele C/C
(frequency)
C/T
(frequency)
T/T
(frequency)
 Caucasian
rs701158 (hCV9628138) UK (Scotland) SZ
CTR
0.42
0.41
0.58
0.59
69 (0.175)
80 (0.167)
192 (0.487)
231 (0.483)
133 (0.338)
167 (0.349)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)
Population   T-Allele C-Allele T/T
(frequency)
T/C
(frequency)
C/C
(frequency)
 Caucasian
rs2759346 UK (Scotland) SZ
CTR
0.36
0.37
0.64
0.63
51 (0.129)
65 (0.136)
182 (0.462)
223 (0.467)
161 (0.409)
190 (0.397)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)
Population   C-Allele T-Allele C/C
(frequency)
C/T
(frequency)
T/T
(frequency)
 Caucasian
rs1538977 (hCV12001932) UK (Scotland) SZ
CTR
0.23
0.23
0.77
0.77
21 (0.053)
25 (0.052)
139 (0.353)
169 (0.354)
234 (0.594)
284 (0.594)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)
Population   C-Allele T-Allele C/C
(frequency)
C/T
(frequency)
T/T
(frequency)
 Caucasian
rs1322784 (hCV12001930) UK (Scotland) SZ
CTR
0.25
0.26
0.75
0.74
25 (0.063)
32 (0.067)
148 (0.376)
184 (0.385)
221 (0.561)
262 (0.548)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)
Population   m-Allele M-Allele m/m
(frequency)
m/M
(frequency)
M/M
(frequency)
 Caucasian
rs1285730 UK (Scotland) SZ
CTR
0.40
0.42
0.60
0.58
63 (0.160)
84 (0.176)
189 (0.480)
233 (0.487)
142 (0.360)
161 (0.337)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)
Population   m-Allele M-Allele m/m
(frequency)
m/M
(frequency)
M/M
(frequency)
 Caucasian
rs12404162 (6070C/T) UK (Scotland) SZ
CTR
0.02
0.02
0.98
0.98
0 (0.000)
0 (0.000)
15 (0.038)
19 (0.040)
378 (0.962)
459 (0.960)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)
Population   G-Allele A-Allele G/G
(frequency)
G/A
(frequency)
A/A
(frequency)
 Caucasian
rs11122396 UK (Scotland) SZ
CTR
0.02
0.02
0.98
0.98
0 (0.000)
0 (0.000)
15 (0.038)
19 (0.040)
378 (0.962)
459 (0.960)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.
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