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Polymorphism Details     
Back Search Methods Disclaimer Credits
 Study: Sanders, 2008
 Gene: HTR2A  (HTR2; 5-HT2A)  Entrez Gene    View on AlzGene   View on PDGene
 Protein: 5-hydroxytryptamine receptor 2A  (5-HT2 receptor; serotonin receptor 2A)  ProteinLink
 Chromosome: 13   (View: 1  2  3  4  5  6  7  8  9  10  11  12  13  14  15  16  17  18  19  20  21  22  X  Y  MT)
 Status: Updated 22 October 2010
Meta-Analysis     Gene Overview
Total number of polymorphisms investigated by this study: 30

Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)		 Population   T-Allele C-Allele T/T
(frequency)		 T/C
(frequency)		 C/C
(frequency)
 Caucasian
rs6313 (102T/C) USA, Australia SZ
CTR		 0.43
0.40		 0.57
0.60		 338 (0.181)
320 (0.160)		 914 (0.489)
961 (0.480)		 618 (0.330)
721 (0.360)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)		 Population   T-Allele C-Allele T/T
(frequency)		 T/C
(frequency)		 C/C
(frequency)
 Caucasian
rs6314 (His452Tyr) USA, Australia SZ
CTR		 0.10
0.09		 0.90
0.91		 18 (0.010)
16 (0.008)		 328 (0.175)
328 (0.164)		 1525 (0.815)
1658 (0.828)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)		 Population   A-Allele G-Allele A/A
(frequency)		 A/G
(frequency)		 G/G
(frequency)
 Caucasian
rs6311 (-1438A/G) USA, Australia SZ
CTR		 0.43
0.40		 0.57
0.60		 338 (0.181)
320 (0.160)		 914 (0.489)
961 (0.480)		 618 (0.330)
721 (0.360)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)		 Population   A-Allele G-Allele A/A
(frequency)		 A/G
(frequency)		 G/G
(frequency)
 Caucasian
rs9534505 USA, Australia SZ
CTR		 0.05
0.05		 0.95
0.95		 5 (0.003)
6 (0.003)		 188 (0.101)
205 (0.102)		 1677 (0.897)
1792 (0.895)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)		 Population   A-Allele G-Allele A/A
(frequency)		 A/G
(frequency)		 G/G
(frequency)
 Caucasian
rs9316235 USA, Australia SZ
CTR		 0.26
0.27		 0.74
0.73		 125 (0.067)
143 (0.071)		 718 (0.384)
784 (0.391)		 1027 (0.549)
1076 (0.537)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)		 Population   G-Allele C-Allele G/G
(frequency)		 G/C
(frequency)		 C/C
(frequency)
 Caucasian
rs9316233 USA, Australia SZ
CTR		 0.19
0.18		 0.81
0.82		 70 (0.037)
67 (0.033)		 583 (0.312)
599 (0.299)		 1218 (0.651)
1336 (0.667)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)		 Population   G-Allele T-Allele G/G
(frequency)		 G/T
(frequency)		 T/T
(frequency)
 Caucasian
rs731779 USA, Australia SZ
CTR		 0.19
0.20		 0.81
0.80		 70 (0.037)
78 (0.039)		 583 (0.312)
636 (0.318)		 1218 (0.651)
1288 (0.643)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)		 Population   C-Allele T-Allele C/C
(frequency)		 C/T
(frequency)		 T/T
(frequency)
 Caucasian
rs659734 USA, Australia SZ
CTR		 0.06
0.05		 0.94
0.95		 6 (0.003)
6 (0.003)		 198 (0.106)
201 (0.100)		 1666 (0.891)
1795 (0.897)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)		 Population   C-Allele T-Allele C/C
(frequency)		 C/T
(frequency)		 T/T
(frequency)
 Caucasian
rs582385 USA, Australia SZ
CTR		 0.17
0.19		 0.83
0.81		 54 (0.029)
69 (0.034)		 528 (0.282)
604 (0.302)		 1288 (0.689)
1330 (0.664)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)		 Population   C-Allele T-Allele C/C
(frequency)		 C/T
(frequency)		 T/T
(frequency)
 Caucasian
rs2770296 USA, Australia SZ
CTR		 0.30
0.30		 0.70
0.70		 166 (0.089)
183 (0.091)		 782 (0.418)
844 (0.422)		 922 (0.493)
975 (0.487)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)		 Population   T-Allele G-Allele T/T
(frequency)		 T/G
(frequency)		 G/G
(frequency)
 Caucasian
rs2296972 USA, Australia SZ
CTR		 0.30
0.29		 0.70
0.71		 164 (0.088)
174 (0.087)		 779 (0.417)
833 (0.416)		 927 (0.496)
995 (0.497)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)		 Population   G-Allele T-Allele G/G
(frequency)		 G/T
(frequency)		 T/T
(frequency)
 Caucasian
rs2070036 USA, Australia SZ
CTR		 0.04
0.04		 0.96
0.96		 3 (0.002)
3 (0.001)		 137 (0.073)
154 (0.077)		 1731 (0.925)
1845 (0.922)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)		 Population   C-Allele A-Allele C/C
(frequency)		 C/A
(frequency)		 A/A
(frequency)
 Caucasian
rs1928042 USA, Australia SZ
CTR		 0.24
0.26		 0.76
0.74		 110 (0.059)
134 (0.067)		 686 (0.367)
768 (0.384)		 1074 (0.574)
1099 (0.549)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)		 Population   T-Allele C-Allele T/T
(frequency)		 T/C
(frequency)		 C/C
(frequency)
 Caucasian
rs1923884 USA, Australia SZ
CTR		 0.14
0.13		 0.86
0.87		 35 (0.019)
35 (0.017)		 442 (0.236)
462 (0.231)		 1393 (0.745)
1505 (0.752)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)		 Population   A-Allele C-Allele A/A
(frequency)		 A/C
(frequency)		 C/C
(frequency)
 Caucasian
rs1805055 (Thr25Asn) USA, Australia SZ
CTR		 0.02
0.02		 0.98
0.98		 1 (0.001)
1 (0.000)		 80 (0.043)
90 (0.045)		 1789 (0.957)
1911 (0.955)


Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   T-Allele C-Allele T/T
(frequency)		 T/C
(frequency)		 C/C
(frequency)
 Caucasian
rs985933 USA, Australia SZ
CTR		 0.40
0.40		 0.60
0.60		 293 (0.157)
319 (0.159)		 895 (0.479)
960 (0.480)		 682 (0.365)
723 (0.361)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   G-Allele T-Allele G/G
(frequency)		 G/T
(frequency)		 T/T
(frequency)
 Caucasian
rs977003 USA, Australia SZ
CTR		 0.46
0.45		 0.54
0.55		 396 (0.212)
407 (0.203)		 929 (0.497)
991 (0.495)		 545 (0.291)
603 (0.301)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   T-Allele C-Allele T/T
(frequency)		 T/C
(frequency)		 C/C
(frequency)
 Caucasian
rs9534511 USA, Australia SZ
CTR		 0.48
0.50		 0.52
0.50		 427 (0.228)
501 (0.250)		 933 (0.499)
1001 (0.500)		 510 (0.273)
501 (0.250)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   C-Allele T-Allele C/C
(frequency)		 C/T
(frequency)		 T/T
(frequency)
 Caucasian
rs927544 USA, Australia SZ
CTR		 0.30
0.30		 0.70
0.70		 163 (0.087)
179 (0.089)		 778 (0.416)
839 (0.419)		 929 (0.497)
984 (0.492)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   A-Allele G-Allele A/A
(frequency)		 A/G
(frequency)		 G/G
(frequency)
 Caucasian
rs7997012 USA, Australia SZ
CTR		 0.40
0.42		 0.60
0.58		 302 (0.161)
345 (0.172)		 899 (0.481)
972 (0.486)		 669 (0.358)
685 (0.342)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   C-Allele T-Allele C/C
(frequency)		 C/T
(frequency)		 T/T
(frequency)
 Caucasian
rs7325168 USA, Australia SZ
CTR		 0.10
0.09		 0.90
0.91		 18 (0.010)
17 (0.008)		 331 (0.177)
331 (0.165)		 1521 (0.813)
1654 (0.826)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   T-Allele C-Allele T/T
(frequency)		 T/C
(frequency)		 C/C
(frequency)
 Caucasian
rs7324218 USA, Australia SZ
CTR		 0.10
0.09		 0.90
0.91		 18 (0.010)
17 (0.008)		 328 (0.175)
331 (0.165)		 1525 (0.815)
1654 (0.826)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   T-Allele A-Allele T/T
(frequency)		 T/A
(frequency)		 A/A
(frequency)
 Caucasian
rs7323441 USA, Australia SZ
CTR		 0.10
0.09		 0.90
0.91		 18 (0.010)
17 (0.008)		 328 (0.175)
334 (0.167)		 1525 (0.815)
1651 (0.825)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   G-Allele A-Allele G/G
(frequency)		 G/A
(frequency)		 A/A
(frequency)
 Caucasian
rs6312 USA, Australia SZ
CTR		 0.06
0.06		 0.94
0.94		 6 (0.003)
6 (0.003)		 204 (0.109)
212 (0.106)		 1659 (0.888)
1784 (0.891)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   G-Allele A-Allele G/G
(frequency)		 G/A
(frequency)		 A/A
(frequency)
 Caucasian
rs6310 USA, Australia SZ
CTR		 0.06
0.05		 0.94
0.95		 6 (0.003)
6 (0.003)		 204 (0.109)
208 (0.104)		 1659 (0.888)
1788 (0.893)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   G-Allele A-Allele G/G
(frequency)		 G/A
(frequency)		 A/A
(frequency)
 Caucasian
rs4941573 USA, Australia SZ
CTR		 0.43
0.40		 0.57
0.60		 338 (0.181)
324 (0.162)		 914 (0.489)
963 (0.481)		 618 (0.330)
716 (0.357)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   C-Allele T-Allele C/C
(frequency)		 C/T
(frequency)		 T/T
(frequency)
 Caucasian
rs1923886 USA, Australia SZ
CTR		 0.44
0.45		 0.56
0.55		 367 (0.196)
405 (0.202)		 923 (0.494)
991 (0.495)		 580 (0.310)
606 (0.303)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   T-Allele C-Allele T/T
(frequency)		 T/C
(frequency)		 C/C
(frequency)
 Caucasian
rs1923882 USA, Australia SZ
CTR		 0.23
0.24		 0.77
0.76		 103 (0.055)
113 (0.056)		 672 (0.360)
726 (0.363)		 1094 (0.585)
1162 (0.581)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   G-Allele T-Allele G/G
(frequency)		 G/T
(frequency)		 T/T
(frequency)
 Caucasian
rs17289304 USA, Australia SZ
CTR		 0.10
0.10		 0.90
0.90		 20 (0.011)
21 (0.010)		 346 (0.185)
370 (0.185)		 1505 (0.804)
1611 (0.805)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   C-Allele T-Allele C/C
(frequency)		 C/T
(frequency)		 T/T
(frequency)
 Caucasian
rs1328684 USA, Australia SZ
CTR		 0.33
0.35		 0.67
0.65		 207 (0.111)
245 (0.122)		 831 (0.444)
911 (0.455)		 832 (0.445)
846 (0.423)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.
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Genes: 1008
Polymorphisms: 8788
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