SZGene

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Polymorphism Details

Study:

Jonsson, 1998

Gene:

CYP2D6 (CPD6; CYP2D; CYP2DL1; P450C2D; P450-DB1)

View on AlzGene View on MSGene View on PDGene

Protein:

cytochrome P450, family 2, subfamily D, polypeptide 6 (cytochrome P450 2D6; microsomal monooxygenase; xenobiotic monooxygenase; debrisoquine 4-hydroxylase; flavoprotein-linked monooxygenase; cytochrome P450, subfamily IID (debrisoquine, sparteine, etc., -metabolizing)-like 1)

Chromosome:

22 (View: 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 X Y MT)

Status:

Updated 21 October 2010 ; Note that of the most commonly investigated haplotypes in this gene, only data for the CYP2D6*4 haplotype are included.

Total number of polymorphisms investigated by this study: 1

Case-Control Studies (by ethnic group)
					Genotypes
Polymorphism ID# (Link to NCBI)	Population		*4-Allele	wt-Allele	4/4 (frequency)	*4/wt (frequency)	wt/wt (frequency)
Caucasian
*rs3892097 (CYP2D64-B)**	Sweden	SZ CTR	0.18 0.17	0.82 0.83	4 (0.032) 2 (0.024)	36 (0.290) 25 (0.294)	84 (0.677) 58 (0.682)


SZGene Recent Updates
SZGene Stats Studies: 1727 Genes: 1008 Polymorphisms: 8788 Meta-analyses: 287





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