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Polymorphism Details     
Back Search Methods Disclaimer Credits
 Study: Jungerius, 2007
 Gene: PRKCA  (AAG6; PKCA; PRKACA; PKC-alpha)  Entrez Gene    View on MSGene
 Protein: protein kinase C, alpha  (aging-associated gene 6)  ProteinLink
 Chromosome: 17   (View: 1  2  3  4  5  6  7  8  9  10  11  12  13  14  15  16  17  18  19  20  21  22  X  Y  MT)
 Status: Updated 1 January 2010
Meta-Analysis     Gene Overview
Total number of polymorphisms investigated by this study: 17

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)
Population   T-Allele C-Allele T/T
(frequency)
T/C
(frequency)
C/C
(frequency)
 Caucasian
rs1860985 Netherlands SZ
CTR
0.07
0.10
0.93
0.90
1 (0.003)
5 (0.010)
39 (0.126)
90 (0.173)
269 (0.871)
425 (0.817)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)
Population   T-Allele A-Allele T/T
(frequency)
T/A
(frequency)
A/A
(frequency)
 Caucasian
rs3803821 Netherlands SZ
CTR
0.53
0.49
0.47
0.51
86 (0.277)
123 (0.237)
155 (0.498)
260 (0.500)
70 (0.225)
137 (0.263)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)
Population   T-Allele C-Allele T/T
(frequency)
T/C
(frequency)
C/C
(frequency)
 Caucasian
rs1010546 Netherlands SZ
CTR
0.12
0.15
0.88
0.85
5 (0.016)
11 (0.021)
66 (0.212)
130 (0.250)
240 (0.772)
379 (0.729)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)
Population   T-Allele A-Allele T/T
(frequency)
T/A
(frequency)
A/A
(frequency)
 Caucasian
rs228875 Netherlands SZ
CTR
0.32
0.35
0.68
0.65
31 (0.100)
63 (0.121)
134 (0.434)
236 (0.455)
144 (0.466)
220 (0.424)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)
Population   T-Allele G-Allele T/T
(frequency)
T/G
(frequency)
G/G
(frequency)
 Caucasian
rs8464 Netherlands SZ
CTR
0.12
0.11
0.88
0.89
5 (0.016)
6 (0.012)
67 (0.216)
98 (0.188)
238 (0.768)
417 (0.800)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)
Population   T-Allele A-Allele T/T
(frequency)
T/A
(frequency)
A/A
(frequency)
 Caucasian
rs6504413 Netherlands SZ
CTR
0.10
0.08
0.90
0.92
3 (0.010)
4 (0.008)
55 (0.177)
79 (0.152)
252 (0.813)
438 (0.841)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)
Population   C-Allele T-Allele C/C
(frequency)
C/T
(frequency)
T/T
(frequency)
 Caucasian
rs7207345 Netherlands SZ
CTR
0.22
0.24
0.78
0.76
15 (0.049)
31 (0.060)
107 (0.346)
192 (0.370)
187 (0.605)
296 (0.570)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)
Population   C-Allele T-Allele C/C
(frequency)
C/T
(frequency)
T/T
(frequency)
 Caucasian
rs4791036 Netherlands SZ
CTR
0.10
0.08
0.90
0.92
3 (0.010)
3 (0.006)
53 (0.171)
78 (0.150)
254 (0.819)
438 (0.844)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)
Population   G-Allele A-Allele G/G
(frequency)
G/A
(frequency)
A/A
(frequency)
 Caucasian
rs759117 Netherlands SZ
CTR
0.37
0.39
0.63
0.61
43 (0.138)
78 (0.150)
145 (0.466)
247 (0.474)
123 (0.395)
196 (0.376)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)
Population   A-Allele G-Allele A/A
(frequency)
A/G
(frequency)
G/G
(frequency)
 Caucasian
rs8074995 Netherlands SZ
CTR
0.13
0.14
0.87
0.86
5 (0.016)
10 (0.019)
70 (0.227)
126 (0.242)
234 (0.757)
384 (0.738)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)
Population   A-Allele G-Allele A/A
(frequency)
A/G
(frequency)
G/G
(frequency)
 Caucasian
rs7342847 Netherlands SZ
CTR
0.35
0.37
0.65
0.63
39 (0.125)
70 (0.135)
142 (0.457)
241 (0.463)
130 (0.418)
209 (0.402)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)
Population   T-Allele A-Allele T/T
(frequency)
T/A
(frequency)
A/A
(frequency)
 Caucasian
rs10491201 Netherlands SZ
CTR
0.08
0.08
0.92
0.92
2 (0.006)
3 (0.006)
47 (0.152)
74 (0.142)
261 (0.842)
443 (0.852)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)
Population   C-Allele T-Allele C/C
(frequency)
C/T
(frequency)
T/T
(frequency)
 Caucasian
rs3764402 Netherlands SZ
CTR
0.24
0.25
0.76
0.75
18 (0.058)
32 (0.061)
114 (0.369)
193 (0.370)
177 (0.573)
296 (0.568)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)
Population   G-Allele A-Allele G/G
(frequency)
G/A
(frequency)
A/A
(frequency)
 Caucasian
rs9893560 Netherlands SZ
CTR
0.11
0.11
0.89
0.89
4 (0.013)
6 (0.012)
60 (0.193)
102 (0.196)
247 (0.794)
412 (0.792)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)
Population   T-Allele G-Allele T/T
(frequency)
T/G
(frequency)
G/G
(frequency)
 Caucasian
rs3889237 Netherlands SZ
CTR
0.39
0.39
0.61
0.61
48 (0.155)
80 (0.154)
148 (0.477)
248 (0.476)
114 (0.368)
193 (0.370)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)
Population   G-Allele A-Allele G/G
(frequency)
G/A
(frequency)
A/A
(frequency)
 Caucasian
rs8074909 Netherlands SZ
CTR
0.36
0.36
0.64
0.64
40 (0.129)
67 (0.129)
143 (0.461)
239 (0.459)
127 (0.410)
215 (0.413)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)
Population   A-Allele G-Allele A/A
(frequency)
A/G
(frequency)
G/G
(frequency)
 Caucasian
rs9914723 Netherlands SZ
CTR
0.19
0.19
0.81
0.81
11 (0.035)
18 (0.035)
94 (0.303)
158 (0.305)
205 (0.661)
342 (0.660)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.
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Studies: 1727
Genes: 1008
Polymorphisms: 8788
Meta-analyses: 287
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