Schizophrenia Research Forum - A Catalyst for Creative Thinking
Home Your Profile Become a Member/Get Newsletter Contact Us
What's New
Recent Updates
SRF Papers
Current Papers
Search All Papers
Search Comments
News
Research News
Forums
Current Hypotheses
Idea Lab
Online Discussions
Virtual Conferences
Interviews
Tech Corner
Resources
What We Know
SchizophreniaGene
Animal Models
Drugs in Trials
Research Tools
Grants
Jobs
Conferences
Journals
Community Calendar
General Information
Community
Member Directory
Researcher Profiles
Institutes and Labs
About the Site
Mission
History
SRF Team
Advisory Board
Support Us
How to Cite
Fan (E)Mail
The Schizophrenia Research Forum web site is sponsored by NARSAD, the Brain and Behavior Research Fund, and was created with funding from the U.S. National Institute of Mental Health.
Printable version  
Polymorphism Details     
Back Search Methods Disclaimer Credits
 Study: Stefansson, 2009
 Gene: PRSS16  (XXbac-BPG24O18.5; FLJ36271; FLJ40714; FLJ44172; TSSP)  Entrez Gene
 Protein: protease, serine, 16 (thymus)  (protease, serine, 16; thymus specific serine peptidase)  ProteinLink
 Chromosome: 6   (View: 1  2  3  4  5  6  7  8  9  10  11  12  13  14  15  16  17  18  19  20  21  22  X  Y  MT)
 Status: Updated 22 October 2010
Meta-Analysis     Gene Overview
Total number of polymorphisms investigated by this study: 2

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)
Population   C-Allele T-Allele C/C
(frequency)
C/T
(frequency)
T/T
(frequency)
 Caucasian
rs13219354 Denmark (Aarhus; Follow-up) SZ
CTR
0.11
0.13
0.89
0.87
3 (0.013)
8 (0.016)
43 (0.188)
111 (0.227)
183 (0.799)
371 (0.757)
rs13219354 Denmark (Copenhagen; Follow-up) SZ
CTR
0.11
0.12
0.89
0.88
6 (0.012)
19 (0.014)
99 (0.197)
281 (0.212)
398 (0.791)
1023 (0.773)
rs13219354 Finland (Follow-up) SZ
CTR
0.05
0.06
0.95
0.94
1 (0.003)
16 (0.004)
26 (0.091)
470 (0.118)
260 (0.906)
3499 (0.878)
rs13219354 Finland (Helsinki; GWAS) SZ
CTR
0.03
0.05
0.97
0.95
0 (0.000)
0 (0.000)
3 (0.052)
16 (0.109)
55 (0.948)
131 (0.891)
rs13219354 Finland (Kuusamo; GWAS) SZ
CTR
0.02
0.07
0.98
0.93
0 (0.000)
0 (0.000)
5 (0.041)
7 (0.140)
117 (0.959)
43 (0.860)
rs13219354 Germany (Bonn; Follow-up) SZ
CTR
0.10
0.11
0.90
0.89
6 (0.010)
20 (0.013)
108 (0.176)
310 (0.202)
501 (0.815)
1204 (0.785)
rs13219354 Germany (Bonn; GWAS) SZ
CTR
0.10
0.12
0.90
0.88
5 (0.010)
5 (0.014)
86 (0.178)
77 (0.210)
392 (0.812)
285 (0.777)
rs13219354 Germany (Munich; Follow-up) SZ
CTR
0.09
0.11
0.91
0.89
2 (0.007)
19 (0.012)
48 (0.158)
310 (0.193)
253 (0.835)
1281 (0.796)
rs13219354 Germany (Munich; GWAS) SZ
CTR
0.08
0.12
0.92
0.88
4 (0.007)
8 (0.013)
85 (0.154)
126 (0.210)
462 (0.838)
466 (0.777)
rs13219354 Hungary (Follow-up) SZ
CTR
0.06
0.10
0.94
0.90
1 (0.004)
2 (0.009)
28 (0.108)
41 (0.183)
231 (0.888)
181 (0.808)
rs13219354 Iceland (GWAS) SZ
CTR
0.08
0.09
0.92
0.91
4 (0.007)
90 (0.008)
89 (0.152)
1849 (0.162)
494 (0.842)
9465 (0.830)
rs13219354 Italy (GWAS) SZ
CTR
0.04
0.10
0.96
0.90
0 (0.000)
1 (0.011)
6 (0.071)
16 (0.180)
78 (0.929)
72 (0.809)
rs13219354 Netherlands-I (Follow-up) SZ
CTR
0.12
0.13
0.88
0.87
10 (0.014)
66 (0.018)
150 (0.210)
849 (0.234)
554 (0.776)
2719 (0.748)
rs13219354 Norway (Follow-up) SZ
CTR
0.10
0.11
0.90
0.89
1 (0.009)
2 (0.012)
21 (0.184)
31 (0.189)
92 (0.807)
131 (0.799)
rs13219354 Russia (Follow-up) SZ
CTR
0.07
0.07
0.93
0.93
2 (0.004)
3 (0.006)
64 (0.134)
66 (0.137)
412 (0.862)
413 (0.857)
rs13219354 Sweden (Follow-up) SZ
CTR
0.06
0.08
0.94
0.92
1 (0.004)
2 (0.007)
31 (0.122)
44 (0.150)
222 (0.874)
247 (0.843)
rs13219354 UK (England; GWAS) SZ
CTR
0.09
0.12
0.91
0.88
1 (0.011)
1 (0.012)
14 (0.159)
17 (0.207)
73 (0.830)
64 (0.780)
rs13219354 UK (Scotland; GWAS) SZ
CTR
0.12
0.14
0.88
0.86
10 (0.015)
12 (0.018)
142 (0.216)
155 (0.235)
505 (0.769)
493 (0.747)
rs13219354 Netherlands-II (Follow-up) SZ
CTR
0.10
0.06
0.90
0.94
1 (0.011)
0 (0.000)
17 (0.187)
11 (0.128)
73 (0.802)
75 (0.872)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)
Population   C-Allele T-Allele C/C
(frequency)
C/T
(frequency)
T/T
(frequency)
 Caucasian
rs6932590 Netherlands-II (Follow-up) SZ
CTR
0.21
0.24
0.79
0.76
4 (0.045)
5 (0.059)
30 (0.337)
31 (0.365)
55 (0.618)
49 (0.576)
rs6932590 UK (Scotland; GWAS) SZ
CTR
0.26
0.26
0.74
0.74
44 (0.067)
46 (0.070)
251 (0.383)
257 (0.389)
361 (0.550)
358 (0.542)
rs6932590 UK (England; GWAS) SZ
CTR
0.25
0.26
0.75
0.74
6 (0.066)
6 (0.069)
34 (0.374)
33 (0.379)
51 (0.560)
48 (0.552)
rs6932590 Sweden (Follow-up) SZ
CTR
0.14
0.16
0.86
0.84
5 (0.020)
7 (0.025)
60 (0.236)
76 (0.267)
189 (0.744)
202 (0.709)
rs6932590 Russia (Follow-up) SZ
CTR
0.18
0.20
0.82
0.80
15 (0.032)
19 (0.040)
135 (0.292)
152 (0.323)
313 (0.676)
300 (0.637)
rs6932590 Spain (Santiago; Follow-up) SZ
CTR
0.24
0.25
0.76
0.75
16 (0.056)
39 (0.064)
104 (0.361)
229 (0.377)
168 (0.583)
339 (0.558)
rs6932590 Spain (Valencia; Follow-up) SZ
CTR
0.27
0.31
0.73
0.69
26 (0.073)
38 (0.095)
140 (0.394)
171 (0.426)
189 (0.532)
192 (0.479)
rs6932590 Norway (Follow-up) SZ
CTR
0.17
0.20
0.83
0.80
3 (0.028)
6 (0.039)
30 (0.278)
49 (0.318)
75 (0.694)
99 (0.643)
rs6932590 Netherlands-I (Follow-up) SZ
CTR
0.23
0.26
0.77
0.74
37 (0.052)
249 (0.069)
251 (0.351)
1404 (0.387)
427 (0.597)
1977 (0.545)
rs6932590 Italy (GWAS) SZ
CTR
0.24
0.30
0.76
0.70
5 (0.060)
8 (0.091)
30 (0.361)
37 (0.420)
48 (0.578)
43 (0.489)
rs6932590 Iceland (GWAS) SZ
CTR
0.15
0.16
0.85
0.84
13 (0.022)
306 (0.027)
151 (0.259)
3124 (0.274)
420 (0.719)
7964 (0.699)
rs6932590 Hungary (Follow-up) SZ
CTR
0.20
0.23
0.80
0.77
10 (0.038)
12 (0.054)
84 (0.318)
80 (0.360)
170 (0.644)
130 (0.586)
rs6932590 Germany (Munich; GWAS) SZ
CTR
0.23
0.26
0.77
0.74
29 (0.051)
41 (0.068)
200 (0.350)
232 (0.384)
342 (0.599)
331 (0.548)
rs6932590 Germany (Munich; Follow-up) SZ
CTR
0.19
0.24
0.81
0.76
10 (0.035)
93 (0.058)
87 (0.309)
585 (0.366)
185 (0.656)
922 (0.576)
rs6932590 Germany (Bonn; GWAS) SZ
CTR
0.21
0.26
0.79
0.74
22 (0.046)
24 (0.066)
163 (0.337)
140 (0.383)
298 (0.617)
202 (0.552)
rs6932590 Germany (Bonn; Follow-up) SZ
CTR
0.22
0.25
0.78
0.75
29 (0.049)
94 (0.063)
204 (0.346)
563 (0.375)
356 (0.604)
844 (0.562)
rs6932590 Finland (Kuusamo; GWAS) SZ
CTR
0.07
0.11
0.93
0.89
1 (0.008)
1 (0.020)
16 (0.132)
9 (0.180)
104 (0.860)
40 (0.800)
rs6932590 Finland (Helsinki; GWAS) SZ
CTR
0.05
0.12
0.95
0.88
0 (0.000)
2 (0.014)
6 (0.102)
32 (0.218)
53 (0.898)
113 (0.769)
rs6932590 Finland (Follow-up) SZ
CTR
0.09
0.11
0.91
0.89
2 (0.007)
47 (0.012)
47 (0.164)
773 (0.194)
237 (0.829)
3161 (0.794)
rs6932590 Denmark (Copenhagen; Follow-up) SZ
CTR
0.22
0.24
0.78
0.76
23 (0.046)
73 (0.056)
168 (0.339)
472 (0.361)
304 (0.614)
764 (0.584)
rs6932590 Denmark (Aarhus; Follow-up) SZ
CTR
0.24
0.24
0.76
0.76
19 (0.056)
36 (0.057)
124 (0.364)
228 (0.364)
198 (0.581)
363 (0.579)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.
SZGene Recent Updates
SZGene Stats
Studies: 1727
Genes: 1008
Polymorphisms: 8788
Meta-analyses: 287
ALSGene
AlzGene
MSGene
PDGene
SZGene
An up-to-date collection of all published genetic association studies.
SRF News
SRF Comments
Text Size
Reset Text Size
Email this pageEmail this page

Share/Bookmark
Research Participants
Collaborators
Copyright © 2005-2022 Schizophrenia Research Forum Privacy Policy Disclaimer Disclosure Copyright