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SZGene - Gene overview of all published SZ-association studies for IL6    
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 Gene: IL6  (BSF2; HGF; HSF; IFNB2; IL-6)  Entrez Gene    View on AlzGene   View on MSGene   View on PDGene
 Protein: interleukin 6 (interferon, beta 2)  (B cell stimulatory factor-2; B-cell differentiation factor; CTL differentiation factor; OTTHUMP00000158544; hybridoma growth factor; interleukin 6; interleukin BSF-2)  ProteinLink
 Chromosome: 7   (View: 1  2  3  4  5  6  7  8  9  10  11  12  13  14  15  16  17  18  19  20  21  22  X  Y  MT)
 Status: Updated 19 July 2010
Meta-Analysis
1. Case-Control Studies (by ethnic group)
      SZ Cases Normal Controls    
Study Population Source # Polys # Subjects
(% women)		 DX Onset Age
(range)		 Age
(range)		 # Subjects
(% women)		 Age
(range)		 Result Comment
 Caucasian
Paul-Samojedny, 2010
 Poland CL  1  (detail)  96
(39%)		IV26.6
(-)		44.8 + 11.6
(-)		120
(33%)		39.2 + 10.3
(-)		Positive
 Asian
Liu, 2009
 Taiwan CL  2  (detail)  100
(52%)		IV-34.5 + 11.3
(-)		113
(55%)		33.3 + 10.6
(-)		Negative
Contact us if you are an author of an association study regarding this gene and do not find your study in this table or find errors in the representation of your study details.
Source:  Source of case population -> “CL” (clinic-based), “PO” (population-based), or “CO” (community-based).
# Polys:  Number of polymorphisms tested per gene and per sample.
Onset Age and Age:  Mean or median age at onset or examination, respectively.
DX:  Criteria used to determine SZ diagnosis ->  "IIIR"(DSM-IIIR), "IV" (DSM-IV), "9" (ICD-9), "10" (ICD-10), "M" (Mixed), "RDC" (Research Diagnostic Criteria), "U" (Unknown).
Result:  Overall conclusion reached by authors of the original publication (“positive” usually indicates significant (P<0.05) association in at least one of the performed analyses, and “negative” indicates no evidence for significant association, while “trend” indicates results in between).
(-) :  Either no data provided or in case of overlap, data included in original study.
SZGene Recent Updates
SZGene Stats
Studies: 1727
Genes: 1008
Polymorphisms: 8788
Meta-analyses: 287
ALSGene
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MSGene
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SZGene
An up-to-date collection of all published genetic association studies.
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