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SZGene - Gene overview of all published SZ-association studies for DAO    
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 Gene: DAO  (DAAO; OXDA; DAMOX)  Entrez Gene    View on ALSGene
 Protein: D-amino-acid oxidase   ProteinLink
 Chromosome: 12   (View: 1  2  3  4  5  6  7  8  9  10  11  12  13  14  15  16  17  18  19  20  21  22  X  Y  MT)
 Status: Updated 21 October 2010
Meta-Analysis
1. Case-Control Studies (by ethnic group)
      SZ Cases Normal Controls    
Study Population Source # Polys # Subjects
(% women)
DX Onset Age
(range)
Age
(range)
# Subjects
(% women)
Age
(range)
Result Comment
 Caucasian
Bass, 2009
UK CL  3  (detail)  431
(-)
M--442
(-)
-Negative
Chumakov, 2002
Canada CL  8  (detail)  213
(-)
IV--241
(-)
-Positive
Corvin, 2007
Ireland CL  4  (detail)  373
(-)
IV--812
(-)
-Positive
Jonsson, 2009
Denmark, Norway, Sweden CL  4  (detail)  837
(42%)
M26.5
(-)
45.7
(-)
1473
(42%)
44.1
(-)
Negative
Schumacher, 2004
Overlaps with
Suliman, 2010
CL  3  (detail)  299
(49%)
IV-38.6 + 11.9
(-)
300
(60%)
47.1 + 15.2
(-)
n.a.
Shinkai, 2007
Canada CL  4  (detail)  168
(-)
IV--168
(-)
-Negative
Suliman, 2010
Germany CL  20  (detail)  531
(45%)
IV--755
(50%)
-Trend
Vilella, 2007
Spain PO  5  (detail)  589
(31%)
IV-46.4 + 17
(-)
615
(48%)
43 + 15
(-)
Negative
Wood, 2006
USA CL  7  (detail)  311
(-)
IV--291
(-)
-Positive
 Asian
Kim, 2010
Korea CL  9  (detail)  448
(42%)
IV-33 + 10.2
(-)
337
(55%)
37 + 14
(-)
Positive
Liu, 2004
China CL  6  (detail)  547
(-)
U--536
(-)
-Positive
Ohnuma, 2009
Overlaps with
Ohnuma, 2010
CL  11  (detail)  340
(48%)
IV-39.4 + 13.9
(-)
340
(51%)
39.8 + 14.7
(-)
Positive
Ohnuma, 2010
Japan CL  3  (detail)  1656
(48%)
IV-45.2 + 15.4
(-)
1842
(57%)
47.1 + 19.1
(-)
Negative
Yamada, 2005
Japan (I) CL  6  (detail)  50
(-)
IV-36.9 + 14.2
(-)
52
(-)
30.3 + 8
(-)
Negative
Yamada, 2005
Japan (II) CL  6  (detail)  570
(50%)
IV-47 + 11.4
(-)
570
(50%)
46.7 + 11.1
(-)
Negative
Contact us if you are an author of an association study regarding this gene and do not find your study in this table or find errors in the representation of your study details.
2. Family-Based Studies (by ethnic group)
      Affecteds Unaffecteds    
Study Population # Polys # Families # Subjects
(% women)
DX Onset Age
(range)
Age
(range)
# Subjects
(% women)
Age
(range)
Result Comment
 Caucasian
Fallin, 2005
USA  5  (detail)  263274
(26%)
IV19.5 + 4.5
(-)
-548
(50%)
-Negative
Shinkai, 2007
Canada  4  (detail)  113113
(-)
IV19.5 + 5.6
(-)
-226
(50%)
-Negative
 Asian
Liu, 2006
Taiwan  3  (detail)  218-IV----Negative
Yamada, 2005
Japan  6  (detail)  124163
(-)
IV--213
(-)
-Negative
Contact us if you are an author of an association study regarding this gene and do not find your study in this table or find errors in the representation of your study details.
Source:  Source of case population -> “CL” (clinic-based), “PO” (population-based), or “CO” (community-based).
# Polys:  Number of polymorphisms tested per gene and per sample.
Onset Age and Age:  Mean or median age at onset or examination, respectively.
DX:  Criteria used to determine SZ diagnosis ->  "IIIR"(DSM-IIIR), "IV" (DSM-IV), "9" (ICD-9), "10" (ICD-10), "M" (Mixed), "RDC" (Research Diagnostic Criteria), "U" (Unknown).
Result:  Overall conclusion reached by authors of the original publication (“positive” usually indicates significant (P<0.05) association in at least one of the performed analyses, and “negative” indicates no evidence for significant association, while “trend” indicates results in between).
(-) :  Either no data provided or in case of overlap, data included in original study.
SZGene Recent Updates
SZGene Stats
Studies: 1727
Genes: 1008
Polymorphisms: 8788
Meta-analyses: 287
ALSGene
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SZGene
An up-to-date collection of all published genetic association studies.
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