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SZGene - Gene overview of all published SZ-association studies for CNTF    
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 Gene: CNTF  (HCNTF)  Entrez Gene    View on ALSGene   View on AlzGene   View on MSGene   View on PDGene
 Protein: ciliary neurotrophic factor   ProteinLink
 Chromosome: 11   (View: 1  2  3  4  5  6  7  8  9  10  11  12  13  14  15  16  17  18  19  20  21  22  X  Y  MT)
 Status: Updated 21 October 2010
Meta-Analysis
1. Case-Control Studies (by ethnic group)
      SZ Cases Normal Controls    
Study Population Source # Polys # Subjects
(% women)
DX Onset Age
(range)
Age
(range)
# Subjects
(% women)
Age
(range)
Result Comment
 Caucasian
Gelertner, 1997
USA CL  1  (detail)  66
(0%)
M--91
(-)
-Negative
Jungerius, 2007
Netherlands CL  2  (detail)  310
(-)
IV--880
(-)
-Negative
Nothen, 1996
Germany CL  1  (detail)  139
(35%)
IIIR-37.3 + 11
(-)
100
(42%)
32.7 + 10.4
(-)
Negative
Thome, 1997a
Sweden CL  1  (detail)  118
(36%)
IIIR-45.8 + 17.7
(-)
99
(35%)
38.2 + 6.3
(-)
Negative
Thome, 1997b
Spain CL  1  (detail)  107
(58%)
10-55.4 + 15.8
(-)
100
(59%)
53.1 + 21
(-)
Negative
Virgos, 2001
Spain CL  1  (detail)  262
(40%)
9-61.4
(19-90)
278
(39%)
54.2
(21-90)
Negative
 Asian
Arinami, 1996
Japan CL  1  (detail)  205
(-)
IIIR-48.9
(25-65)
184
(-)
50.1
(31-65)
Negative
Li, 1996
China CL  1  (detail)  91
(44%)
IIIR-24.9 + 5.7
(-)
89
(35%)
25.6 + 7.1
(-)
Negative
Nishiyama, 2006
Japan CL  1  (detail)  222
(45%)
IV-46.4 + 14.7
(-)
237
(77%)
38.4 + 12.3
(-)
Negative
Sakai, 1997
Japan CL  1  (detail)  138
(57%)
IIIR-37.5 + 10.4
(19-64)
140
(51%)
28.4 + 6.6
(19-55)
Negative
Tanaka, 1998
Japan CL  1  (detail)  86
(51%)
10-40.1 + 12.8
(-)
100
(64%)
37.3 + 12.3
(-)
Negative
Contact us if you are an author of an association study regarding this gene and do not find your study in this table or find errors in the representation of your study details.
Source:  Source of case population -> “CL” (clinic-based), “PO” (population-based), or “CO” (community-based).
# Polys:  Number of polymorphisms tested per gene and per sample.
Onset Age and Age:  Mean or median age at onset or examination, respectively.
DX:  Criteria used to determine SZ diagnosis ->  "IIIR"(DSM-IIIR), "IV" (DSM-IV), "9" (ICD-9), "10" (ICD-10), "M" (Mixed), "RDC" (Research Diagnostic Criteria), "U" (Unknown).
Result:  Overall conclusion reached by authors of the original publication (“positive” usually indicates significant (P<0.05) association in at least one of the performed analyses, and “negative” indicates no evidence for significant association, while “trend” indicates results in between).
(-) :  Either no data provided or in case of overlap, data included in original study.
SZGene Recent Updates
SZGene Stats
Studies: 1727
Genes: 1008
Polymorphisms: 8788
Meta-analyses: 287
ALSGene
AlzGene
MSGene
PDGene
SZGene
An up-to-date collection of all published genetic association studies.
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