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SZGene - Overview of all published large-scale and genome-wide association studies in SZ
Back Search Methods Disclaimer Credits
 Status: Updated 11 October 2010;  ** See Large Scale Study Methods **
GWAS (genome-wide association studies)
              SZ Cases Normal Controls    
Study Design Type Population Source Platform # of SNPs Genotype Data Publicly Available DX # Subjects
(GWAS)		 # Subjects
(follow-up)		 # Subjects
(GWAS)		 # Subjects
(follow-up)		 Featured Genes Comment
 Caucasian
Athanasiu, 2010
CCGWAS Norway (TOP), Europe (SGENE-plus) CL Affymetrix 6.0572,888 No M201266330513780
Djurovic, 2010
CCGWAS Norway CL Affymetrix 6.0618,860 No IV23003360  
ISC, 2009
CCGWAS, and meta-analysis (ISC, MGS, SGENE) Europe (ISC) CL Affymetrix 500K, 5.0, 6.0739,995 No M3322-3587-
Jia, 2010
 GWAS re-analysis (pathways) USA (GAIN) CL see primary studysee primary study Yes M1158013780  
Kirov, 2008
FBATGWAS Bulgaria CL Illumina HumanHap (550K)433680 No IV574-1753-
Lencz, 2007
CCGWAS USA CL Affymetrix (500K)439511 No IV178-144-
Mah, 2006
CCGWAS USA CL Selected cSNPs25494 No IV320-325-
Need, 2009
CCGWAS (multi-stage) Mixed CL Illumina HumanHap (300,550K)312,565 No M871146086312995  
Shifman, 2008
CCGWAS (multi-stage) Israel CL Affymetrix (500K)510552 No IV660-2771-
Stefansson, 2009
CCGWAS, and meta-analysis (ISC, MGS, SGENE) Europe (SGENE-plus) CL Illumina HumanHap (300,550K)314,868 No M266349991349815555
 Asian
Ikeda, 2010
CCGWAS Japan CL Affymetrix 5.0297,645 No IV57519905645389
 Other/Mixed
O'Donovan, 2008
CCGWAS (multi-stage) Mixed CL Affymetrix (500K)362,532 No IV7308-12834-
Shi, 2009
CCGWAS, and meta-analysis (ISC, MGS, SGENE) USA (MGS) CL,PO Affymetrix 6.0696,788-843,798 Yes M3967-3626-
Sullivan, 2008
CCGWAS USA (CATIE) CL Affymetrix (500K) & Perlegen (customized)492900 Yes IV738-733-  
Contact us if you are an author of an association study regarding this gene and do not find your study in this table or find errors in the representation of your study details.
Other large-scale studies
              SZ Cases Normal Controls    
Study Design Type Population Source Platform # of SNPs Genotype Data Publicly Available DX # Subjects
(GWAS)		 # Subjects
(follow-up)		 # Subjects
(GWAS)		 # Subjects
(follow-up)		 Featured Genes Comment
 Caucasian
Christoforou, 2007
CCFine-mapping (4p15-16) Overlaps with
Christoforou, 2010		 CL Illumina (customized)408 Yes IV386-458-
Christoforou, 2010
CCFine-mapping (4p15-16) UK (Scotland) CL Illumina (customized)633 No IV1257-1372-  
Gratacos, 2009
CCNeurotransmission/neurodevelopment pathways Spain CL,PO ABI (SNPlex)748 No IV91709370
Kao, 2010
CC, FBATFine-mapping (NRG3) USA CL Illumina Golden Gate252 No IV445-1100-
O'Dushlaine, 2010
CCGWAS re-analysis (pathways) Mixed (ISC, GAIN) CL see primary studiessee primary studies No U3322135135871378
Williams, 2010
CCFine-mapping (ZNF804A) Mixed CL,PO Sequenom176 No IV479182714454969
 Asian
Koga, 2009
CCChromatin remodeling pathways Japan CL Illumina (109k, HumanHap370)11,883 No IV10019207401920
Liu, 2009
CCGWAS (STR screen, pooled) China CL ABI (PRISM Linkage Mapping Set MD-10)400 No IV119190119190
 Other/Mixed
Chen, 2010
CC, FBATGWAS re-analysis, and follow-up Mixed (CATIE, MGS, other) CL,PO see primary studiessee primary studies No M165812292165515893
Torri, 2010
FBATFine-mapping (6q23.3) Israel (TKT, BT) CL Illumina (HumanHap370, and customized Golden Gate array)2,019 No M9916599256
Wason, 2010
CCGWAS re-analysis (multimarker models) USA (MGS) CL,PO see primary studysee primary study No M2681026530  
Contact us if you are an author of an association study regarding this gene and do not find your study in this table or find errors in the representation of your study details.
Design: “CC” (case-control), “FBAT” (family-based)
Type: “GWAS” (genome-wide association study); “CWA” (chromosome-wide association study); “LSA” (other large-scale association study); “cSNP” (coding-region SNP)
Source: Source of case population -> “CL” (clinic-based), “PO” (population-based), or “CO” (community-based).
Platform: Please refer to orignal publication for exact description.
# SNPs: Approximate number of polymorphisms covered.
DX: Criteria used to determine SZ diagnosis -> "IIIR" (DSM-IIIR), "IV" (DSM-IV), "9" (ICD-9), "10" (ICD-10), "M" (Mixed), "RDC" (Research Diagnostic Criteria), "U" (Unknown).
Featured Genes: Dropdown menu of genes highlighted (“featured”) in original publication as potential SZ susceptibility genes/loci after completion of all analyses, e.g. replication in multiple samples.
(-) : No information provided/not applicable.
SZGene Recent Updates
SZGene Stats
Studies: 1727
Genes: 1008
Polymorphisms: 8788
Meta-analyses: 287
ALSGene
AlzGene
MSGene
PDGene
SZGene
An up-to-date collection of all published genetic association studies.
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