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Meta-Analysis of All Published SZ Association Studies (Case-Control Only) rs3749034
Back Search Methods Disclaimer Credits
 Polymorphism: rs3749034 (hCV2177452)
 Gene: GAD1  (GAD; SCP)  Entrez Gene
 Protein: glutamate decarboxylase 1   ProteinLink
 Chromosome: 2   (View: 1  2  3  4  5  6  7  8  9  10  11  12  13  14  15  16  17  18  19  20  21  22  X  Y  MT)
 Status: Updated 22 October 2010
Gene Overview
 Polymorphism:
1) Summary of Allele and Genotype Distribution of all Published Association Studies (by Ethnic Group)
      Alleles Genotypes
  # Case-Control
Samples		   A-Allele
(frequency)		 G-Allele
(frequency)		 A/A
(frequency)		 A/G
(frequency)		 G/G
(frequency)
 Caucasian 3 SZ
CTR		 0.23
0.24		 0.77
0.76		 42 (0.064)
37 (0.054)		 218 (0.331)
261 (0.378)		 399 (0.605)
393 (0.569)
 Asian 1 SZ
CTR		 0.33
0.32		 0.67
0.69		 52 (0.093)
39 (0.084)		 265 (0.472)
216 (0.464)		 244 (0.435)
211 (0.453)
Total 4 SZ
CTR		 0.28
0.27		 0.73
0.73		 94 (0.077)
76 (0.066)		 483 (0.396)
477 (0.412)		 643 (0.527)
604 (0.522)

Meta-Analysis Methods      * New * Cumulative Meta-analysis
2) Forest plot for polymorphism  rs3749034 (hCV2177452)

Please also see disclaimer for more information on these meta-analyses.

Meta-analyses have not been performed on the following polymorphisms since they lack published genotype data in at least four independent case-control samples, or the published genotype data was otherwise not eligible for inclusion (see methods for details):

GAD1_27379C/T
GAD1_292A/C
GAD1_41702A/G
GAD1_496C/T
GAD1_661C/T
rs10191129 (hCV2177434)
rs10432420 (hCV2177469)
rs12185692
rs16823181
rs16858996
rs17701824
rs1978340 (hCV11637130)
rs2241164
rs2241165
rs2270335
rs2356236
rs3749035
rs3762553
rs3762554
rs3762555
rs3762556
rs3762561
rs3791850
rs3791851
rs3791857
rs3791858
rs3791878
rs3828275 (hCV2177441)
rs4668331
rs6755102
rs701492 (hCV8823482)
rs7557793 (hCV2177464)
rs769390
rs769395 (hCV8823522)
rs769404 (hCV8823462)
rs769407
rs869395
rs872123

SZGene Recent Updates
SZGene Stats
Studies: 1727
Genes: 1008
Polymorphisms: 8788
Meta-analyses: 287
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An up-to-date collection of all published genetic association studies.
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