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Meta-Analysis of All Published SZ Association Studies (Case-Control Only) rs17666
Back Search Methods Disclaimer Credits
 Polymorphism: rs17666 (2236T/C)
 Gene: DPYSL2  (DRP2; CRMP2; DHPRP2)  Entrez Gene
 Protein: dihydropyrimidinase-like 2  (collapsin response mediator protein hCRMP-2)  ProteinLink
 Chromosome: 8   (View: 1  2  3  4  5  6  7  8  9  10  11  12  13  14  15  16  17  18  19  20  21  22  X  Y  MT)
 Status: Updated 21 October 2010
Gene Overview
 Polymorphism:
1) Summary of Allele and Genotype Distribution of all Published Association Studies (by Ethnic Group)
      Alleles Genotypes
  # Case-Control
Samples
  C-Allele
(frequency)
T-Allele
(frequency)
C/C
(frequency)
C/T
(frequency)
T/T
(frequency)
 Caucasian 1 SZ
CTR
0.42
0.26
0.58
0.74
13 (0.173)
3 (0.071)
37 (0.493)
16 (0.381)
25 (0.333)
23 (0.548)
 African Descent 1 SZ
CTR
0.53
0.50
0.47
0.50
11 (0.282)
6 (0.273)
19 (0.487)
10 (0.455)
9 (0.231)
6 (0.273)
 Asian 3 SZ
CTR
0.14
0.15
0.86
0.85
32 (0.024)
31 (0.024)
313 (0.239)
323 (0.247)
963 (0.736)
955 (0.730)
Total 5 SZ
CTR
0.17
0.16
0.83
0.84
56 (0.039)
40 (0.029)
369 (0.259)
349 (0.254)
997 (0.701)
984 (0.717)

Meta-Analysis Methods      * New * Cumulative Meta-analysis
2) Forest plot for polymorphism  rs17666 (2236T/C)

Please also see disclaimer for more information on these meta-analyses.


Meta-analyses have not been performed on the following polymorphisms since they lack published genotype data in at least four independent case-control samples, or the published genotype data was otherwise not eligible for inclusion (see methods for details):

DPYSL2_975C/G
rs11863
rs13249543
rs1442337
rs1442887
rs17321828
rs182748
rs1972921
rs2289592
rs2289593 (352G/A)
rs2585458
rs327217
rs327221
rs327222 (426C/T)
rs327232
rs327233
rs327234
rs371255
rs3866466
rs403185
rs4733013
rs4733033
rs4733048
rs708621 (1506T/C)
rs7829347
rs920633
rs920697

SZGene Recent Updates
SZGene Stats
Studies: 1727
Genes: 1008
Polymorphisms: 8788
Meta-analyses: 287
ALSGene
AlzGene
MSGene
PDGene
SZGene
An up-to-date collection of all published genetic association studies.
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