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Meta-Analysis of All Published SZ Association Studies (Case-Control Only) rs4532
Back Search Methods Disclaimer Credits
 Polymorphism: rs4532 (48A/G)
 Gene: DRD1  (DADR; DRD1A)  Entrez Gene    View on PDGene
 Protein: dopamine receptor D1   ProteinLink
 Chromosome: 5   (View: 1  2  3  4  5  6  7  8  9  10  11  12  13  14  15  16  17  18  19  20  21  22  X  Y  MT)
 Status: Updated 21 October 2010
Gene Overview
 Polymorphism:
1) Summary of Allele and Genotype Distribution of all Published Association Studies (by Ethnic Group)
      Alleles Genotypes
  # Case-Control
Samples
  G-Allele
(frequency)
A-Allele
(frequency)
G/G
(frequency)
G/A
(frequency)
A/A
(frequency)
 Caucasian 3 SZ
CTR
0.39
0.38
0.61
0.63
88 (0.166)
108 (0.138)
240 (0.454)
370 (0.473)
201 (0.380)
304 (0.389)
 Asian 3 SZ
CTR
0.13
0.12
0.87
0.88
7 (0.012)
7 (0.010)
129 (0.227)
148 (0.220)
433 (0.761)
517 (0.769)
Total 6 SZ
CTR
0.26
0.26
0.75
0.74
95 (0.087)
115 (0.079)
369 (0.336)
518 (0.356)
634 (0.577)
821 (0.565)

Meta-Analysis Methods      * New * Cumulative Meta-analysis
2) Forest plot for polymorphism  rs4532 (48A/G)

Please also see disclaimer for more information on these meta-analyses.


Meta-analyses have not been performed on the following polymorphisms since they lack published genotype data in at least four independent case-control samples, or the published genotype data was otherwise not eligible for inclusion (see methods for details):

DRD1_2bpSTR (Dwn55kb)
DRD1_4bpSTR (Dwn57kb)
DRD1_EcoRI
rs10063995 (-2102C/A)
rs11746641
rs11749676
rs12518222
rs13306309
rs155417 (1263G/A)
rs2168631
rs251937
rs265967
rs265981 (-800T/C)
rs267416
rs267418
rs35916350 (-1251G/C)
rs4867798
rs5326 (-94G/A)
rs5330
rs5331
rs686 (1403T/C)
rs6882300

SZGene Recent Updates
SZGene Stats
Studies: 1727
Genes: 1008
Polymorphisms: 8788
Meta-analyses: 287
ALSGene
AlzGene
MSGene
PDGene
SZGene
An up-to-date collection of all published genetic association studies.
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