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Meta-Analysis of All Published SZ Association Studies (Case-Control Only) rs133945
Back Search Methods Disclaimer Credits
 Polymorphism: rs133945 (-196G/A)
 Gene: SYN3   Entrez Gene    View on AlzGene   View on MSGene   View on PDGene
 Protein: synapsin III   ProteinLink
 Chromosome: 22   (View: 1  2  3  4  5  6  7  8  9  10  11  12  13  14  15  16  17  18  19  20  21  22  X  Y  MT)
 Status: Updated 22 October 2010
Gene Overview
 Polymorphism:
1) Summary of Allele and Genotype Distribution of all Published Association Studies (by Ethnic Group)
      Alleles Genotypes
  # Case-Control
Samples
  A-Allele
(frequency)
G-Allele
(frequency)
A/A
(frequency)
A/G
(frequency)
G/G
(frequency)
 Caucasian 2 SZ
CTR
0.48
0.52
0.52
0.48
178 (0.224)
223 (0.270)
404 (0.508)
406 (0.492)
213 (0.268)
196 (0.238)
 African Descent 1 SZ
CTR
0.42
0.41
0.58
0.59
21 (0.169)
21 (0.158)
63 (0.508)
68 (0.511)
40 (0.323)
44 (0.331)
 Asian 4 SZ
CTR
0.30
0.31
0.70
0.69
72 (0.078)
92 (0.101)
416 (0.448)
387 (0.425)
440 (0.474)
432 (0.474)
Total 7 SZ
CTR
0.39
0.41
0.61
0.59
271 (0.147)
336 (0.180)
883 (0.478)
861 (0.461)
693 (0.375)
672 (0.360)

Meta-Analysis Methods      * New * Cumulative Meta-analysis
2) Forest plot for polymorphism  rs133945 (-196G/A)

Please also see disclaimer for more information on these meta-analyses.


Meta-analyses have not been performed on the following polymorphisms since they lack published genotype data in at least four independent case-control samples, or the published genotype data was otherwise not eligible for inclusion (see methods for details):

D22S280
rs1056484
rs133946 (-631C/G)
SYN3_1573G/C
SYN3_271T/C
SYN3_408C/T
SYN3_469G/A
SYN3_470G/A
SYN3_4bpSTR (GATG)
SYN3_69G/A
SYN3_E525Q

SZGene Recent Updates
SZGene Stats
Studies: 1727
Genes: 1008
Polymorphisms: 8788
Meta-analyses: 287
ALSGene
AlzGene
MSGene
PDGene
SZGene
An up-to-date collection of all published genetic association studies.
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