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Polymorphism Details     
Back Search Methods Disclaimer Credits
 Study: Tolosa, 2010
 Gene: FOXP2  (SPCH1; CAGH44; TNRC10; DKFZp686H1726)  Entrez Gene
 Protein: forkhead box P2  (CAG repeat protein 44; speech and language disorder 1; trinucleotide repeat containing 10; forkhead/winged-helix transcription factor)  ProteinLink
 Chromosome: 7   (View: 1  2  3  4  5  6  7  8  9  10  11  12  13  14  15  16  17  18  19  20  21  22  X  Y  MT)
 Status: Updated 4 August 2010
Meta-Analysis     Gene Overview
Total number of polymorphisms investigated by this study: 24

Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)
Population   A-Allele T-Allele A/A
(frequency)
A/T
(frequency)
T/T
(frequency)
 Caucasian
rs7803667 Spain SZ
CTR
0.33
0.30
0.67
0.70
29 (0.099)
31 (0.090)
138 (0.471)
143 (0.416)
126 (0.430)
170 (0.494)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)
Population   T-Allele C-Allele T/T
(frequency)
T/C
(frequency)
C/C
(frequency)
 Caucasian
rs10447760 Spain SZ
CTR
0.30
0.24
0.70
0.76
21 (0.072)
20 (0.059)
132 (0.454)
126 (0.371)
138 (0.474)
194 (0.571)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)
Population   G-Allele C-Allele G/G
(frequency)
G/C
(frequency)
C/C
(frequency)
 Caucasian
rs1597548 Spain SZ
CTR
0.05
0.06
0.95
0.94
0 (0.000)
1 (0.003)
29 (0.099)
37 (0.110)
264 (0.901)
299 (0.887)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)
Population   C-Allele T-Allele C/C
(frequency)
C/T
(frequency)
T/T
(frequency)
 Caucasian
rs2396722 Spain SZ
CTR
0.36
0.36
0.64
0.64
38 (0.130)
48 (0.141)
135 (0.461)
150 (0.440)
120 (0.410)
143 (0.419)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)
Population   T-Allele A-Allele T/T
(frequency)
T/A
(frequency)
A/A
(frequency)
 Caucasian
rs1852469 Spain SZ
CTR
0.04
0.03
0.96
0.97
1 (0.003)
0 (0.000)
23 (0.078)
20 (0.059)
270 (0.918)
320 (0.941)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)
Population   C-Allele A-Allele C/C
(frequency)
C/A
(frequency)
A/A
(frequency)
 Caucasian
rs2396753 Spain SZ
CTR
0.49
0.43
0.51
0.57
67 (0.229)
54 (0.159)
152 (0.521)
187 (0.550)
73 (0.250)
99 (0.291)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)
Population   C-Allele T-Allele C/C
(frequency)
C/T
(frequency)
T/T
(frequency)
 Caucasian
rs1456031 Spain SZ
CTR
0.43
0.47
0.57
0.53
59 (0.203)
78 (0.227)
132 (0.454)
167 (0.485)
100 (0.344)
99 (0.288)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)
Population   C-Allele T-Allele C/C
(frequency)
C/T
(frequency)
T/T
(frequency)
 Caucasian
rs17137124 Spain SZ
CTR
0.47
0.50
0.53
0.50
67 (0.231)
88 (0.259)
138 (0.476)
167 (0.491)
85 (0.293)
85 (0.250)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)
Population   C-Allele A-Allele C/C
(frequency)
C/A
(frequency)
A/A
(frequency)
 Caucasian
rs923875 Spain SZ
CTR
0.41
0.39
0.59
0.61
44 (0.150)
51 (0.150)
155 (0.529)
163 (0.479)
94 (0.321)
126 (0.371)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)
Population   A-Allele G-Allele A/A
(frequency)
A/G
(frequency)
G/G
(frequency)
 Caucasian
rs10255943 Spain SZ
CTR
0.31
0.31
0.69
0.69
24 (0.091)
35 (0.111)
113 (0.430)
126 (0.400)
126 (0.479)
154 (0.489)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)
Population   C-Allele T-Allele C/C
(frequency)
C/T
(frequency)
T/T
(frequency)
 Caucasian
rs10486026 Spain SZ
CTR
0.21
0.23
0.79
0.77
11 (0.042)
22 (0.070)
89 (0.338)
98 (0.311)
163 (0.620)
195 (0.619)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)
Population   T-Allele C-Allele T/T
(frequency)
T/C
(frequency)
C/C
(frequency)
 Caucasian
rs10500038 Spain SZ
CTR
0.20
0.17
0.80
0.83
11 (0.041)
6 (0.019)
85 (0.317)
99 (0.310)
172 (0.642)
214 (0.671)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)
Population   T-Allele C-Allele T/T
(frequency)
T/C
(frequency)
C/C
(frequency)
 Caucasian
rs11771168 Spain SZ
CTR
0.21
0.23
0.79
0.77
13 (0.049)
16 (0.050)
87 (0.330)
112 (0.351)
164 (0.621)
191 (0.599)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)
Population   T-Allele C-Allele T/T
(frequency)
T/C
(frequency)
C/C
(frequency)
 Caucasian
rs12670585 Spain SZ
CTR
0.28
0.30
0.72
0.70
21 (0.080)
32 (0.101)
107 (0.408)
126 (0.399)
134 (0.511)
158 (0.500)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)
Population   G-Allele T-Allele G/G
(frequency)
G/T
(frequency)
T/T
(frequency)
 Caucasian
rs1456021 Spain SZ
CTR
0.37
0.41
0.63
0.59
36 (0.130)
60 (0.180)
133 (0.480)
157 (0.470)
108 (0.390)
117 (0.350)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)
Population   G-Allele A-Allele G/G
(frequency)
G/A
(frequency)
A/A
(frequency)
 Caucasian
rs1456029 Spain SZ
CTR
0.26
0.23
0.74
0.77
21 (0.079)
19 (0.060)
98 (0.370)
108 (0.340)
146 (0.551)
191 (0.601)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)
Population   A-Allele G-Allele A/A
(frequency)
A/G
(frequency)
G/G
(frequency)
 Caucasian
rs1668335 Spain SZ
CTR
0.28
0.29
0.72
0.71
24 (0.091)
28 (0.088)
100 (0.380)
126 (0.396)
139 (0.529)
164 (0.516)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)
Population   G-Allele A-Allele G/G
(frequency)
G/A
(frequency)
A/A
(frequency)
 Caucasian
rs1916977 Spain SZ
CTR
0.24
0.25
0.76
0.75
16 (0.061)
25 (0.080)
95 (0.360)
107 (0.341)
153 (0.580)
182 (0.580)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)
Population   A-Allele G-Allele A/A
(frequency)
A/G
(frequency)
G/G
(frequency)
 Caucasian
rs2253478 Spain SZ
CTR
0.38
0.38
0.62
0.62
38 (0.130)
54 (0.159)
144 (0.491)
150 (0.441)
111 (0.379)
136 (0.400)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)
Population   C-Allele T-Allele C/C
(frequency)
C/T
(frequency)
T/T
(frequency)
 Caucasian
rs2396765 Spain SZ
CTR
0.38
0.41
0.62
0.59
37 (0.141)
57 (0.180)
126 (0.479)
149 (0.470)
100 (0.380)
111 (0.350)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)
Population   A-Allele T-Allele A/A
(frequency)
A/T
(frequency)
T/T
(frequency)
 Caucasian
rs2694941 Spain SZ
CTR
0.42
0.42
0.58
0.58
47 (0.180)
60 (0.190)
125 (0.479)
145 (0.460)
89 (0.341)
110 (0.349)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)
Population   A-Allele G-Allele A/A
(frequency)
A/G
(frequency)
G/G
(frequency)
 Caucasian
rs4730626 Spain SZ
CTR
0.18
0.21
0.82
0.79
8 (0.031)
19 (0.060)
76 (0.290)
95 (0.301)
178 (0.679)
202 (0.639)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)
Population   A-Allele G-Allele A/A
(frequency)
A/G
(frequency)
G/G
(frequency)
 Caucasian
rs6961558 Spain SZ
CTR
0.02
0.03
0.98
0.97
0 (0.000)
0 (0.000)
9 (0.031)
17 (0.050)
283 (0.969)
322 (0.950)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)
Population   G-Allele T-Allele G/G
(frequency)
G/T
(frequency)
T/T
(frequency)
 Caucasian
rs7799652 Spain SZ
CTR
0.43
0.47
0.57
0.53
48 (0.181)
64 (0.201)
130 (0.491)
169 (0.530)
87 (0.328)
86 (0.270)
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Genes: 1008
Polymorphisms: 8788
Meta-analyses: 287
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