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Printable version  
Polymorphism Details     
Back Search Methods Disclaimer Credits
 Study: Gunnell, 2007
 Gene: IGF1  (IGFI)  Entrez Gene    View on AlzGene
 Protein: insulin-like growth factor 1  (somatomedin C)  ProteinLink
 Chromosome: 12   (View: 1  2  3  4  5  6  7  8  9  10  11  12  13  14  15  16  17  18  19  20  21  22  X  Y  MT)
 Status: Updated 23 February 2010
Meta-Analysis     Gene Overview
Total number of polymorphisms investigated by this study: 16

Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)
Population   C-Allele T-Allele C/C
(frequency)
C/T
(frequency)
T/T
(frequency)
 Caucasian
rs2139573 UK, Ireland SZ
CTR
0.47
0.48
0.53
0.52
146 (0.225)
164 (0.230)
323 (0.498)
355 (0.499)
179 (0.276)
193 (0.271)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)
Population   m-Allele M-Allele m/m
(frequency)
m/M
(frequency)
M/M
(frequency)
 Caucasian
rs10860861 UK, Ireland SZ
CTR
0.49
0.52
0.51
0.48
157 (0.242)
189 (0.265)
324 (0.500)
356 (0.500)
167 (0.258)
167 (0.235)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)
Population   A-Allele C-Allele A/A
(frequency)
A/C
(frequency)
C/C
(frequency)
 Caucasian
rs10860862 UK, Ireland SZ
CTR
0.18
0.18
0.82
0.82
20 (0.031)
24 (0.034)
187 (0.289)
214 (0.301)
441 (0.681)
474 (0.666)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)
Population   C-Allele G-Allele C/C
(frequency)
C/G
(frequency)
G/G
(frequency)
 Caucasian
rs5742714 UK, Ireland SZ
CTR
0.08
0.08
0.92
0.92
4 (0.006)
4 (0.006)
92 (0.142)
103 (0.145)
552 (0.852)
605 (0.850)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)
Population   m-Allele M-Allele m/m
(frequency)
m/M
(frequency)
M/M
(frequency)
 Caucasian
rs6214 UK, Ireland SZ
CTR
0.42
0.45
0.58
0.55
115 (0.177)
145 (0.204)
316 (0.488)
353 (0.496)
217 (0.335)
214 (0.301)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)
Population   G-Allele T-Allele G/G
(frequency)
G/T
(frequency)
T/T
(frequency)
 Caucasian
rs5742694 UK, Ireland SZ
CTR
0.28
0.28
0.72
0.72
52 (0.080)
55 (0.077)
264 (0.407)
287 (0.403)
332 (0.512)
370 (0.520)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)
Population   A-Allele G-Allele A/A
(frequency)
A/G
(frequency)
G/G
(frequency)
 Caucasian
rs978458 UK, Ireland SZ
CTR
0.23
0.23
0.77
0.77
33 (0.051)
38 (0.053)
226 (0.349)
254 (0.357)
389 (0.600)
420 (0.590)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)
Population   m-Allele M-Allele m/m
(frequency)
m/M
(frequency)
M/M
(frequency)
 Caucasian
rs7136446 UK, Ireland SZ
CTR
0.42
0.42
0.58
0.58
113 (0.174)
124 (0.174)
315 (0.486)
346 (0.486)
220 (0.340)
242 (0.340)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)
Population   T-Allele C-Allele T/T
(frequency)
T/C
(frequency)
C/C
(frequency)
 Caucasian
rs2033178 UK, Ireland SZ
CTR
0.05
0.05
0.95
0.95
2 (0.003)
2 (0.003)
61 (0.094)
62 (0.087)
585 (0.903)
648 (0.910)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)
Population   A-Allele G-Allele A/A
(frequency)
A/G
(frequency)
G/G
(frequency)
 Caucasian
rs9989002 UK, Ireland SZ
CTR
0.24
0.23
0.76
0.77
38 (0.059)
36 (0.051)
238 (0.367)
249 (0.350)
372 (0.574)
427 (0.600)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)
Population   A-Allele G-Allele A/A
(frequency)
A/G
(frequency)
G/G
(frequency)
 Caucasian
rs4764697 UK, Ireland SZ
CTR
0.23
0.23
0.77
0.77
35 (0.054)
38 (0.053)
232 (0.358)
252 (0.354)
381 (0.588)
422 (0.593)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)
Population   G-Allele A-Allele G/G
(frequency)
G/A
(frequency)
A/A
(frequency)
 Caucasian
rs2195240 UK, Ireland SZ
CTR
0.21
0.21
0.79
0.79
28 (0.043)
30 (0.042)
214 (0.330)
234 (0.329)
406 (0.627)
448 (0.629)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)
Population   T-Allele G-Allele T/T
(frequency)
T/G
(frequency)
G/G
(frequency)
 Caucasian
rs1019731 UK, Ireland SZ
CTR
0.17
0.15
0.83
0.85
18 (0.028)
17 (0.024)
180 (0.278)
185 (0.260)
450 (0.694)
510 (0.716)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)
Population   T-Allele A-Allele T/T
(frequency)
T/A
(frequency)
A/A
(frequency)
 Caucasian
rs10860869 UK, Ireland SZ
CTR
0.25
0.27
0.75
0.73
42 (0.065)
50 (0.070)
245 (0.378)
278 (0.390)
361 (0.557)
384 (0.539)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)
Population   G-Allele A-Allele G/G
(frequency)
G/A
(frequency)
A/A
(frequency)
 Caucasian
rs2162679 UK, Ireland SZ
CTR
0.11
0.11
0.89
0.89
7 (0.011)
9 (0.013)
125 (0.193)
144 (0.202)
516 (0.796)
559 (0.785)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)
Population   T-Allele C-Allele T/T
(frequency)
T/C
(frequency)
C/C
(frequency)
 Caucasian
rs35767 UK, Ireland SZ
CTR
0.10
0.10
0.90
0.90
6 (0.009)
7 (0.010)
117 (0.181)
129 (0.181)
525 (0.810)
576 (0.809)


Family-Based Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)
Population   C-Allele T-Allele C/C
(frequency)
C/T
(frequency)
T/T
(frequency)
 Caucasian
rs2139573 Bulgaria SZ
CTR
-
-
-
-
0 (-)
0 (-)
0 (-)
0 (-)
0 (-)
0 (-)
(-) :  Either no data provided, or data otherwise not eligible for inclusion (see methods for details).

Family-Based Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)
Population   m-Allele M-Allele m/m
(frequency)
m/M
(frequency)
M/M
(frequency)
 Caucasian
rs10860861 Bulgaria SZ
CTR
-
-
-
-
0 (-)
0 (-)
0 (-)
0 (-)
0 (-)
0 (-)
(-) :  Either no data provided, or data otherwise not eligible for inclusion (see methods for details).

Family-Based Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)
Population   A-Allele C-Allele A/A
(frequency)
A/C
(frequency)
C/C
(frequency)
 Caucasian
rs10860862 Bulgaria SZ
CTR
-
-
-
-
0 (-)
0 (-)
0 (-)
0 (-)
0 (-)
0 (-)
(-) :  Either no data provided, or data otherwise not eligible for inclusion (see methods for details).

Family-Based Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)
Population   C-Allele G-Allele C/C
(frequency)
C/G
(frequency)
G/G
(frequency)
 Caucasian
rs5742714 Bulgaria SZ
CTR
-
-
-
-
0 (-)
0 (-)
0 (-)
0 (-)
0 (-)
0 (-)
(-) :  Either no data provided, or data otherwise not eligible for inclusion (see methods for details).

Family-Based Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)
Population   m-Allele M-Allele m/m
(frequency)
m/M
(frequency)
M/M
(frequency)
 Caucasian
rs6214 Bulgaria SZ
CTR
-
-
-
-
0 (-)
0 (-)
0 (-)
0 (-)
0 (-)
0 (-)
(-) :  Either no data provided, or data otherwise not eligible for inclusion (see methods for details).

Family-Based Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)
Population   G-Allele T-Allele G/G
(frequency)
G/T
(frequency)
T/T
(frequency)
 Caucasian
rs5742694 Bulgaria SZ
CTR
-
-
-
-
0 (-)
0 (-)
0 (-)
0 (-)
0 (-)
0 (-)
(-) :  Either no data provided, or data otherwise not eligible for inclusion (see methods for details).

Family-Based Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)
Population   A-Allele G-Allele A/A
(frequency)
A/G
(frequency)
G/G
(frequency)
 Caucasian
rs978458 Bulgaria SZ
CTR
-
-
-
-
0 (-)
0 (-)
0 (-)
0 (-)
0 (-)
0 (-)
(-) :  Either no data provided, or data otherwise not eligible for inclusion (see methods for details).

Family-Based Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)
Population   m-Allele M-Allele m/m
(frequency)
m/M
(frequency)
M/M
(frequency)
 Caucasian
rs7136446 Bulgaria SZ
CTR
-
-
-
-
0 (-)
0 (-)
0 (-)
0 (-)
0 (-)
0 (-)
(-) :  Either no data provided, or data otherwise not eligible for inclusion (see methods for details).

Family-Based Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)
Population   T-Allele C-Allele T/T
(frequency)
T/C
(frequency)
C/C
(frequency)
 Caucasian
rs2033178 Bulgaria SZ
CTR
-
-
-
-
0 (-)
0 (-)
0 (-)
0 (-)
0 (-)
0 (-)
(-) :  Either no data provided, or data otherwise not eligible for inclusion (see methods for details).

Family-Based Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)
Population   A-Allele G-Allele A/A
(frequency)
A/G
(frequency)
G/G
(frequency)
 Caucasian
rs9989002 Bulgaria SZ
CTR
-
-
-
-
0 (-)
0 (-)
0 (-)
0 (-)
0 (-)
0 (-)
(-) :  Either no data provided, or data otherwise not eligible for inclusion (see methods for details).

Family-Based Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)
Population   A-Allele G-Allele A/A
(frequency)
A/G
(frequency)
G/G
(frequency)
 Caucasian
rs4764697 Bulgaria SZ
CTR
-
-
-
-
0 (-)
0 (-)
0 (-)
0 (-)
0 (-)
0 (-)
(-) :  Either no data provided, or data otherwise not eligible for inclusion (see methods for details).

Family-Based Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)
Population   G-Allele A-Allele G/G
(frequency)
G/A
(frequency)
A/A
(frequency)
 Caucasian
rs2195240 Bulgaria SZ
CTR
-
-
-
-
0 (-)
0 (-)
0 (-)
0 (-)
0 (-)
0 (-)
(-) :  Either no data provided, or data otherwise not eligible for inclusion (see methods for details).

Family-Based Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)
Population   T-Allele G-Allele T/T
(frequency)
T/G
(frequency)
G/G
(frequency)
 Caucasian
rs1019731 Bulgaria SZ
CTR
-
-
-
-
0 (-)
0 (-)
0 (-)
0 (-)
0 (-)
0 (-)
(-) :  Either no data provided, or data otherwise not eligible for inclusion (see methods for details).

Family-Based Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)
Population   T-Allele A-Allele T/T
(frequency)
T/A
(frequency)
A/A
(frequency)
 Caucasian
rs10860869 Bulgaria SZ
CTR
-
-
-
-
0 (-)
0 (-)
0 (-)
0 (-)
0 (-)
0 (-)
(-) :  Either no data provided, or data otherwise not eligible for inclusion (see methods for details).

Family-Based Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)
Population   G-Allele A-Allele G/G
(frequency)
G/A
(frequency)
A/A
(frequency)
 Caucasian
rs2162679 Bulgaria SZ
CTR
-
-
-
-
0 (-)
0 (-)
0 (-)
0 (-)
0 (-)
0 (-)
(-) :  Either no data provided, or data otherwise not eligible for inclusion (see methods for details).

Family-Based Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)
Population   T-Allele C-Allele T/T
(frequency)
T/C
(frequency)
C/C
(frequency)
 Caucasian
rs35767 Bulgaria SZ
CTR
-
-
-
-
0 (-)
0 (-)
0 (-)
0 (-)
0 (-)
0 (-)
(-) :  Either no data provided, or data otherwise not eligible for inclusion (see methods for details).
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