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Polymorphism Details     
Back Search Methods Disclaimer Credits
 Study: Jungerius, 2007
 Gene: GFRA1  (GDNFR; RET1L; RETL1; TRNR1; GDNFRA; GFR-ALPHA-1)  Entrez Gene
 Protein: GDNF family receptor alpha 1  (RET ligand 1; GPI-linked anchor protein; PI-linked cell-surface accessory protein; TGF-beta related neurotrophic factor receptor 1; Glial cell line-derived neurotrophic factor receptor alpha)  ProteinLink
 Chromosome: 10   (View: 1  2  3  4  5  6  7  8  9  10  11  12  13  14  15  16  17  18  19  20  21  22  X  Y  MT)
 Status: Updated 22 October 2010
Meta-Analysis     Gene Overview
Total number of polymorphisms investigated by this study: 14

Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)		 Population   A-Allele G-Allele A/A
(frequency)		 A/G
(frequency)		 G/G
(frequency)
 Caucasian
rs3781523 Netherlands SZ
CTR		 0.26
0.24		 0.74
0.76		 21 (0.068)
29 (0.056)		 120 (0.388)
188 (0.362)		 168 (0.544)
303 (0.583)


Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   G-Allele C-Allele G/G
(frequency)		 G/C
(frequency)		 C/C
(frequency)
 Caucasian
rs2530340 Netherlands SZ
CTR		 0.03
0.05		 0.97
0.95		 0 (0.000)
1 (0.002)		 17 (0.055)
48 (0.092)		 292 (0.945)
470 (0.906)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   G-Allele A-Allele G/G
(frequency)		 G/A
(frequency)		 A/A
(frequency)
 Caucasian
rs2530341 Netherlands SZ
CTR		 0.09
0.07		 0.91
0.93		 2 (0.006)
2 (0.004)		 50 (0.162)
66 (0.127)		 257 (0.832)
451 (0.869)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   G-Allele A-Allele G/G
(frequency)		 G/A
(frequency)		 A/A
(frequency)
 Caucasian
rs3781556 Netherlands SZ
CTR		 0.11
0.14		 0.89
0.86		 4 (0.013)
10 (0.019)		 63 (0.203)
126 (0.242)		 243 (0.784)
384 (0.738)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   G-Allele C-Allele G/G
(frequency)		 G/C
(frequency)		 C/C
(frequency)
 Caucasian
rs2302105 Netherlands SZ
CTR		 0.21
0.18		 0.79
0.82		 14 (0.045)
17 (0.033)		 103 (0.332)
155 (0.299)		 193 (0.623)
347 (0.669)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   C-Allele T-Allele C/C
(frequency)		 C/T
(frequency)		 T/T
(frequency)
 Caucasian
rs881726 Netherlands SZ
CTR		 0.23
0.26		 0.77
0.74		 16 (0.052)
34 (0.066)		 109 (0.352)
198 (0.382)		 185 (0.597)
287 (0.553)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   C-Allele T-Allele C/C
(frequency)		 C/T
(frequency)		 T/T
(frequency)
 Caucasian
rs730357 Netherlands SZ
CTR		 0.30
0.28		 0.70
0.72		 29 (0.094)
41 (0.079)		 131 (0.423)
210 (0.405)		 150 (0.484)
268 (0.516)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   C-Allele T-Allele C/C
(frequency)		 C/T
(frequency)		 T/T
(frequency)
 Caucasian
rs2694798 Netherlands SZ
CTR		 0.18
0.16		 0.82
0.84		 10 (0.032)
13 (0.025)		 90 (0.290)
139 (0.267)		 210 (0.677)
368 (0.708)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   C-Allele T-Allele C/C
(frequency)		 C/T
(frequency)		 T/T
(frequency)
 Caucasian
rs10490904 Netherlands SZ
CTR		 0.11
0.12		 0.89
0.88		 4 (0.013)
8 (0.015)		 59 (0.190)
110 (0.211)		 248 (0.797)
403 (0.774)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   A-Allele G-Allele A/A
(frequency)		 A/G
(frequency)		 G/G
(frequency)
 Caucasian
rs10885886 Netherlands SZ
CTR		 0.28
0.29		 0.72
0.71		 24 (0.078)
45 (0.087)		 125 (0.405)
216 (0.416)		 160 (0.518)
258 (0.497)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   G-Allele A-Allele G/G
(frequency)		 G/A
(frequency)		 A/A
(frequency)
 Caucasian
rs2074986 Netherlands SZ
CTR		 0.06
0.06		 0.94
0.94		 1 (0.003)
2 (0.004)		 37 (0.119)
57 (0.110)		 272 (0.877)
461 (0.887)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   C-Allele T-Allele C/C
(frequency)		 C/T
(frequency)		 T/T
(frequency)
 Caucasian
rs2694773 Netherlands SZ
CTR		 0.10
0.10		 0.90
0.90		 3 (0.010)
6 (0.012)		 55 (0.177)
96 (0.184)		 252 (0.813)
419 (0.804)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   C-Allele T-Allele C/C
(frequency)		 C/T
(frequency)		 T/T
(frequency)
 Caucasian
rs7893360 Netherlands SZ
CTR		 0.10
0.09		 0.90
0.91		 3 (0.010)
5 (0.010)		 54 (0.174)
88 (0.170)		 253 (0.816)
424 (0.820)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   A-Allele G-Allele A/A
(frequency)		 A/G
(frequency)		 G/G
(frequency)
 Caucasian
rs2901100 Netherlands SZ
CTR		 0.38
0.38		 0.62
0.62		 45 (0.145)
74 (0.142)		 146 (0.469)
244 (0.469)		 120 (0.386)
202 (0.388)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.
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SZGene Stats
Studies: 1727
Genes: 1008
Polymorphisms: 8788
Meta-analyses: 287
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