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Polymorphism Details     
Back Search Methods Disclaimer Credits
 Study: Jungerius, 2007
 Gene: GFRA1  (GDNFR; RET1L; RETL1; TRNR1; GDNFRA; GFR-ALPHA-1)  Entrez Gene
 Protein: GDNF family receptor alpha 1  (RET ligand 1; GPI-linked anchor protein; PI-linked cell-surface accessory protein; TGF-beta related neurotrophic factor receptor 1; Glial cell line-derived neurotrophic factor receptor alpha)  ProteinLink
 Chromosome: 10   (View: 1  2  3  4  5  6  7  8  9  10  11  12  13  14  15  16  17  18  19  20  21  22  X  Y  MT)
 Status: Updated 22 October 2010
Meta-Analysis     Gene Overview
Total number of polymorphisms investigated by this study: 14

Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)
Population   A-Allele G-Allele A/A
(frequency)
A/G
(frequency)
G/G
(frequency)
 Caucasian
rs3781523 Netherlands SZ
CTR
0.26
0.24
0.74
0.76
21 (0.068)
29 (0.056)
120 (0.388)
188 (0.362)
168 (0.544)
303 (0.583)


Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)
Population   G-Allele C-Allele G/G
(frequency)
G/C
(frequency)
C/C
(frequency)
 Caucasian
rs2530340 Netherlands SZ
CTR
0.03
0.05
0.97
0.95
0 (0.000)
1 (0.002)
17 (0.055)
48 (0.092)
292 (0.945)
470 (0.906)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)
Population   G-Allele A-Allele G/G
(frequency)
G/A
(frequency)
A/A
(frequency)
 Caucasian
rs2530341 Netherlands SZ
CTR
0.09
0.07
0.91
0.93
2 (0.006)
2 (0.004)
50 (0.162)
66 (0.127)
257 (0.832)
451 (0.869)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)
Population   G-Allele A-Allele G/G
(frequency)
G/A
(frequency)
A/A
(frequency)
 Caucasian
rs3781556 Netherlands SZ
CTR
0.11
0.14
0.89
0.86
4 (0.013)
10 (0.019)
63 (0.203)
126 (0.242)
243 (0.784)
384 (0.738)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)
Population   G-Allele C-Allele G/G
(frequency)
G/C
(frequency)
C/C
(frequency)
 Caucasian
rs2302105 Netherlands SZ
CTR
0.21
0.18
0.79
0.82
14 (0.045)
17 (0.033)
103 (0.332)
155 (0.299)
193 (0.623)
347 (0.669)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)
Population   C-Allele T-Allele C/C
(frequency)
C/T
(frequency)
T/T
(frequency)
 Caucasian
rs881726 Netherlands SZ
CTR
0.23
0.26
0.77
0.74
16 (0.052)
34 (0.066)
109 (0.352)
198 (0.382)
185 (0.597)
287 (0.553)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)
Population   C-Allele T-Allele C/C
(frequency)
C/T
(frequency)
T/T
(frequency)
 Caucasian
rs730357 Netherlands SZ
CTR
0.30
0.28
0.70
0.72
29 (0.094)
41 (0.079)
131 (0.423)
210 (0.405)
150 (0.484)
268 (0.516)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)
Population   C-Allele T-Allele C/C
(frequency)
C/T
(frequency)
T/T
(frequency)
 Caucasian
rs2694798 Netherlands SZ
CTR
0.18
0.16
0.82
0.84
10 (0.032)
13 (0.025)
90 (0.290)
139 (0.267)
210 (0.677)
368 (0.708)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)
Population   C-Allele T-Allele C/C
(frequency)
C/T
(frequency)
T/T
(frequency)
 Caucasian
rs10490904 Netherlands SZ
CTR
0.11
0.12
0.89
0.88
4 (0.013)
8 (0.015)
59 (0.190)
110 (0.211)
248 (0.797)
403 (0.774)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)
Population   A-Allele G-Allele A/A
(frequency)
A/G
(frequency)
G/G
(frequency)
 Caucasian
rs10885886 Netherlands SZ
CTR
0.28
0.29
0.72
0.71
24 (0.078)
45 (0.087)
125 (0.405)
216 (0.416)
160 (0.518)
258 (0.497)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)
Population   G-Allele A-Allele G/G
(frequency)
G/A
(frequency)
A/A
(frequency)
 Caucasian
rs2074986 Netherlands SZ
CTR
0.06
0.06
0.94
0.94
1 (0.003)
2 (0.004)
37 (0.119)
57 (0.110)
272 (0.877)
461 (0.887)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)
Population   C-Allele T-Allele C/C
(frequency)
C/T
(frequency)
T/T
(frequency)
 Caucasian
rs2694773 Netherlands SZ
CTR
0.10
0.10
0.90
0.90
3 (0.010)
6 (0.012)
55 (0.177)
96 (0.184)
252 (0.813)
419 (0.804)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)
Population   C-Allele T-Allele C/C
(frequency)
C/T
(frequency)
T/T
(frequency)
 Caucasian
rs7893360 Netherlands SZ
CTR
0.10
0.09
0.90
0.91
3 (0.010)
5 (0.010)
54 (0.174)
88 (0.170)
253 (0.816)
424 (0.820)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)
Population   A-Allele G-Allele A/A
(frequency)
A/G
(frequency)
G/G
(frequency)
 Caucasian
rs2901100 Netherlands SZ
CTR
0.38
0.38
0.62
0.62
45 (0.145)
74 (0.142)
146 (0.469)
244 (0.469)
120 (0.386)
202 (0.388)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.
SZGene Recent Updates
SZGene Stats
Studies: 1727
Genes: 1008
Polymorphisms: 8788
Meta-analyses: 287
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An up-to-date collection of all published genetic association studies.
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