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Polymorphism Details     
Back Search Methods Disclaimer Credits
 Study: Domingeuz, 2006
 Gene: HTR2A  (HTR2; 5-HT2A)  Entrez Gene    View on AlzGene   View on PDGene
 Protein: 5-hydroxytryptamine receptor 2A  (5-HT2 receptor; serotonin receptor 2A)  ProteinLink
 Chromosome: 13   (View: 1  2  3  4  5  6  7  8  9  10  11  12  13  14  15  16  17  18  19  20  21  22  X  Y  MT)
 Status: Updated 22 October 2010
Meta-Analysis     Gene Overview
Total number of polymorphisms investigated by this study: 27

Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)		 Population   T-Allele C-Allele T/T
(frequency)		 T/C
(frequency)		 C/C
(frequency)
 Caucasian
rs6313 (102T/C) Spain SZ
CTR		 0.54
0.46		 0.46
0.54		 76 (0.292)
74 (0.209)		 129 (0.496)
176 (0.497)		 55 (0.212)
104 (0.294)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)		 Population   C-Allele G-Allele C/C
(frequency)		 C/G
(frequency)		 G/G
(frequency)
 Caucasian
rs3125 Spain SZ
CTR		 0.13
0.17		 0.87
0.83		 4 (0.015)
10 (0.028)		 60 (0.231)
99 (0.280)		 196 (0.754)
245 (0.692)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)		 Population   T-Allele C-Allele T/T
(frequency)		 T/C
(frequency)		 C/C
(frequency)
 Caucasian
rs6314 (His452Tyr) Spain SZ
CTR		 0.07
0.10		 0.93
0.90		 1 (0.004)
4 (0.011)		 34 (0.131)
64 (0.181)		 225 (0.865)
286 (0.808)


Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   C-Allele T-Allele C/C
(frequency)		 C/T
(frequency)		 T/T
(frequency)
 Caucasian
rs985934 Spain SZ
CTR		 0.36
0.37		 0.64
0.63		 34 (0.131)
48 (0.136)		 120 (0.462)
164 (0.463)		 106 (0.408)
142 (0.401)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   A-Allele G-Allele A/A
(frequency)		 A/G
(frequency)		 G/G
(frequency)
 Caucasian
rs9534505 Spain SZ
CTR		 0.11
0.10		 0.89
0.90		 3 (0.012)
4 (0.011)		 53 (0.204)
65 (0.184)		 204 (0.785)
285 (0.805)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   A-Allele G-Allele A/A
(frequency)		 A/G
(frequency)		 G/G
(frequency)
 Caucasian
rs9316235 Spain SZ
CTR		 0.25
0.21		 0.75
0.79		 16 (0.062)
16 (0.045)		 97 (0.373)
120 (0.339)		 147 (0.565)
218 (0.616)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   G-Allele C-Allele G/G
(frequency)		 G/C
(frequency)		 C/C
(frequency)
 Caucasian
rs9316233 Spain SZ
CTR		 0.18
0.20		 0.83
0.80		 8 (0.031)
14 (0.040)		 75 (0.288)
111 (0.314)		 177 (0.681)
229 (0.647)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   G-Allele A-Allele G/G
(frequency)		 G/A
(frequency)		 A/A
(frequency)
 Caucasian
rs7333412 Spain SZ
CTR		 0.21
0.27		 0.79
0.73		 12 (0.046)
26 (0.073)		 86 (0.331)
140 (0.395)		 162 (0.623)
188 (0.531)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   G-Allele T-Allele G/G
(frequency)		 G/T
(frequency)		 T/T
(frequency)
 Caucasian
rs731779 Spain SZ
CTR		 0.18
0.16		 0.82
0.84		 8 (0.031)
9 (0.025)		 76 (0.292)
96 (0.271)		 176 (0.677)
249 (0.703)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   A-Allele C-Allele A/A
(frequency)		 A/C
(frequency)		 C/C
(frequency)
 Caucasian
rs731244 Spain SZ
CTR		 0.09
0.11		 0.91
0.89		 2 (0.008)
4 (0.011)		 44 (0.169)
70 (0.198)		 214 (0.823)
280 (0.791)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   C-Allele T-Allele C/C
(frequency)		 C/T
(frequency)		 T/T
(frequency)
 Caucasian
rs659734 Spain SZ
CTR		 0.04
0.07		 0.96
0.93		 0 (0.000)
2 (0.006)		 19 (0.073)
44 (0.124)		 241 (0.927)
308 (0.870)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   T-Allele C-Allele T/T
(frequency)		 T/C
(frequency)		 C/C
(frequency)
 Caucasian
rs6561333 Spain SZ
CTR		 0.41
0.43		 0.59
0.57		 44 (0.169)
64 (0.181)		 126 (0.485)
173 (0.489)		 90 (0.346)
117 (0.331)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   T-Allele C-Allele T/T
(frequency)		 T/C
(frequency)		 C/C
(frequency)
 Caucasian
rs6305 Spain SZ
CTR		 0.03
0.03		 0.97
0.97		 0 (0.000)
0 (0.000)		 16 (0.062)
21 (0.059)		 244 (0.938)
333 (0.941)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   C-Allele T-Allele C/C
(frequency)		 C/T
(frequency)		 T/T
(frequency)
 Caucasian
rs582385 Spain SZ
CTR		 0.14
0.17		 0.86
0.83		 5 (0.019)
10 (0.028)		 62 (0.238)
97 (0.274)		 193 (0.742)
247 (0.698)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   A-Allele T-Allele A/A
(frequency)		 A/T
(frequency)		 T/T
(frequency)
 Caucasian
rs3889066 Spain SZ
CTR		 0.26
0.27		 0.74
0.73		 18 (0.069)
26 (0.073)		 100 (0.385)
141 (0.398)		 142 (0.546)
187 (0.528)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   C-Allele T-Allele C/C
(frequency)		 C/T
(frequency)		 T/T
(frequency)
 Caucasian
rs2770296 Spain SZ
CTR		 0.32
0.28		 0.68
0.72		 27 (0.104)
27 (0.076)		 114 (0.438)
141 (0.398)		 119 (0.458)
186 (0.525)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   T-Allele G-Allele T/T
(frequency)		 T/G
(frequency)		 G/G
(frequency)
 Caucasian
rs2296972 Spain SZ
CTR		 0.23
0.30		 0.77
0.70		 14 (0.054)
31 (0.088)		 94 (0.362)
148 (0.418)		 152 (0.585)
175 (0.494)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   C-Allele T-Allele C/C
(frequency)		 C/T
(frequency)		 T/T
(frequency)
 Caucasian
rs2070037 Spain SZ
CTR		 0.21
0.19		 0.79
0.81		 12 (0.046)
13 (0.037)		 87 (0.335)
108 (0.305)		 161 (0.619)
233 (0.658)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   G-Allele T-Allele G/G
(frequency)		 G/T
(frequency)		 T/T
(frequency)
 Caucasian
rs2070036 Spain SZ
CTR		 0.03
0.04		 0.97
0.96		 0 (0.000)
1 (0.003)		 16 (0.062)
25 (0.071)		 244 (0.938)
328 (0.927)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   C-Allele A-Allele C/C
(frequency)		 C/A
(frequency)		 A/A
(frequency)
 Caucasian
rs1928042 Spain SZ
CTR		 0.20
0.24		 0.80
0.76		 11 (0.042)
20 (0.056)		 84 (0.323)
127 (0.359)		 165 (0.635)
207 (0.585)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   T-Allele C-Allele T/T
(frequency)		 T/C
(frequency)		 C/C
(frequency)
 Caucasian
rs1928040 Spain SZ
CTR		 0.48
0.49		 0.52
0.51		 60 (0.231)
85 (0.240)		 130 (0.500)
177 (0.500)		 70 (0.269)
92 (0.260)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   T-Allele C-Allele T/T
(frequency)		 T/C
(frequency)		 C/C
(frequency)
 Caucasian
rs1923884 Spain SZ
CTR		 0.12
0.12		 0.88
0.88		 4 (0.015)
5 (0.014)		 55 (0.212)
77 (0.218)		 201 (0.773)
272 (0.768)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   A-Allele C-Allele A/A
(frequency)		 A/C
(frequency)		 C/C
(frequency)
 Caucasian
rs1805055 (Thr25Asn) Spain SZ
CTR		 0.02
0.02		 0.98
0.98		 0 (0.000)
0 (0.000)		 8 (0.031)
12 (0.034)		 252 (0.969)
342 (0.966)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   A-Allele C-Allele A/A
(frequency)		 A/C
(frequency)		 C/C
(frequency)
 Caucasian
rs1360020 Spain SZ
CTR		 0.47
0.49		 0.53
0.51		 57 (0.219)
85 (0.240)		 130 (0.500)
177 (0.500)		 73 (0.281)
92 (0.260)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   G-Allele A-Allele G/G
(frequency)		 G/A
(frequency)		 A/A
(frequency)
 Caucasian
rs1328685 Spain SZ
CTR		 0.10
0.12		 0.90
0.88		 3 (0.012)
5 (0.014)		 48 (0.185)
74 (0.209)		 209 (0.804)
275 (0.777)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   A-Allele G-Allele A/A
(frequency)		 A/G
(frequency)		 G/G
(frequency)
 Caucasian
rs10507546 Spain SZ
CTR		 0.23
0.20		 0.78
0.80		 13 (0.050)
14 (0.040)		 91 (0.350)
113 (0.319)		 156 (0.600)
227 (0.641)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   A-Allele C-Allele A/A
(frequency)		 A/C
(frequency)		 C/C
(frequency)
 Caucasian
rs10507544 Spain SZ
CTR		 0.34
0.31		 0.66
0.69		 31 (0.119)
35 (0.099)		 117 (0.450)
153 (0.432)		 112 (0.431)
166 (0.469)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.
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