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Polymorphism Details     
Back Search Methods Disclaimer Credits
 Study: Mikesell, 1996
 Gene: PENK   Entrez Gene
 Protein: proenkephalin   ProteinLink
 Chromosome: 8   (View: 1  2  3  4  5  6  7  8  9  10  11  12  13  14  15  16  17  18  19  20  21  22  X  Y  MT)
 Status: Updated 7 March 2007
Meta-Analysis     Gene Overview
Total number of polymorphisms investigated by this study: 6

Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)		 Population   A-Allele C-Allele A/A
(frequency)		 A/C
(frequency)		 C/C
(frequency)
 African Descent
PENK_E1_98C/A USA (II) SZ
CTR		 0.14
0.26		 0.86
0.74		 1 (0.040)
2 (0.095)		 5 (0.200)
7 (0.333)		 19 (0.760)
12 (0.571)
 Caucasian
PENK_E1_98C/A USA (I) SZ
CTR		 0.49
0.39		 0.51
0.61		 29 (0.252)
6 (0.214)		 55 (0.478)
10 (0.357)		 31 (0.270)
12 (0.429)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)		 Population   del-Allele C-Allele del/del
(frequency)		 del/C
(frequency)		 C/C
(frequency)
 African Descent
PENK_3'UTR_Cdel USA (II) SZ
CTR		 0.10
0.19		 0.90
0.81		 0 (0.000)
2 (0.095)		 5 (0.200)
4 (0.190)		 20 (0.800)
15 (0.714)
 Caucasian
PENK_3'UTR_Cdel USA (I) SZ
CTR		 0.49
0.39		 0.51
0.61		 29 (0.252)
6 (0.214)		 55 (0.478)
10 (0.357)		 31 (0.270)
12 (0.429)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)		 Population   G-Allele A-Allele G/G
(frequency)		 G/A
(frequency)		 A/A
(frequency)
 African Descent
PENK_3'UTR_A/G USA (II) SZ
CTR		 0.10
0.10		 0.90
0.90		 0 (0.000)
0 (0.000)		 5 (0.200)
4 (0.190)		 20 (0.800)
17 (0.810)
 Caucasian
PENK_3'UTR_A/G USA (I) SZ
CTR		 0.30
0.38		 0.70
0.63		 13 (0.113)
5 (0.179)		 44 (0.383)
11 (0.393)		 58 (0.504)
12 (0.429)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)		 Population   T-Allele C-Allele T/T
(frequency)		 T/C
(frequency)		 C/C
(frequency)
 African Descent
PENK_Ser27C/T USA (II) SZ
CTR		 0.38
0.24		 0.62
0.76		 6 (0.240)
3 (0.143)		 7 (0.280)
4 (0.190)		 12 (0.480)
14 (0.667)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)		 Population   T-Allele C-Allele T/T
(frequency)		 T/C
(frequency)		 C/C
(frequency)
 African Descent
PENK_Ser243C/T USA (II) SZ
CTR		 0.10
0.07		 0.90
0.93		 1 (0.040)
0 (0.000)		 3 (0.120)
3 (0.143)		 21 (0.840)
18 (0.857)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)		 Population   T-Allele C-Allele T/T
(frequency)		 T/C
(frequency)		 C/C
(frequency)
 African Descent
PENK_Tyr261C/T USA (II) SZ
CTR		 0.10
0.07		 0.90
0.93		 1 (0.040)
0 (0.000)		 3 (0.120)
3 (0.143)		 21 (0.840)
18 (0.857)
SZGene Recent Updates
SZGene Stats
Studies: 1727
Genes: 1008
Polymorphisms: 8788
Meta-analyses: 287
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