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Polymorphism Details     
Back Search Methods Disclaimer Credits
 Study: Benzel, 2007
 Gene: EGFR  (ERBB; mENA; ERBB1)  Entrez Gene
 Protein: epidermal growth factor receptor  (cell growth inhibiting protein 40; avian erythroblastic leukemia viral (v-erb-b) oncogene homolog)  ProteinLink
 Chromosome: 7   (View: 1  2  3  4  5  6  7  8  9  10  11  12  13  14  15  16  17  18  19  20  21  22  X  Y  MT)
 Status: Updated 13 February 2008
Meta-Analysis     Gene Overview
Total number of polymorphisms investigated by this study: 22

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   T-Allele C-Allele T/T
(frequency)		 T/C
(frequency)		 C/C
(frequency)
 Caucasian
rs524529 UK SZ
CTR		 0.22
0.21		 0.78
0.79		 19 (0.048)
58 (0.043)		 136 (0.344)
443 (0.330)		 240 (0.608)
840 (0.626)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   m-Allele M-Allele m/m
(frequency)		 m/M
(frequency)		 M/M
(frequency)
 Caucasian
rs7787739 UK SZ
CTR		 0.01
0.02		 0.99
0.98		 0 (0.000)
0 (0.000)		 5 (0.013)
45 (0.034)		 391 (0.987)
1296 (0.966)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   m-Allele M-Allele m/m
(frequency)		 m/M
(frequency)		 M/M
(frequency)
 Caucasian
rs2192293 UK SZ
CTR		 0.46
0.47		 0.54
0.53		 84 (0.212)
293 (0.218)		 197 (0.497)
668 (0.498)		 115 (0.290)
381 (0.284)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   m-Allele M-Allele m/m
(frequency)		 m/M
(frequency)		 M/M
(frequency)
 Caucasian
rs7806790 UK SZ
CTR		 0.01
0.01		 0.99
0.99		 0 (0.000)
0 (0.000)		 11 (0.028)
39 (0.029)		 385 (0.972)
1303 (0.971)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   A-Allele G-Allele A/A
(frequency)		 A/G
(frequency)		 G/G
(frequency)
 Caucasian
rs729969 UK SZ
CTR		 0.15
0.13		 0.85
0.87		 9 (0.023)
23 (0.017)		 103 (0.260)
308 (0.230)		 284 (0.717)
1011 (0.753)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   G-Allele A-Allele G/G
(frequency)		 G/A
(frequency)		 A/A
(frequency)
 Caucasian
rs1344307 UK SZ
CTR		 0.19
0.20		 0.81
0.80		 14 (0.035)
52 (0.039)		 120 (0.303)
424 (0.316)		 262 (0.662)
867 (0.646)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   T-Allele C-Allele T/T
(frequency)		 T/C
(frequency)		 C/C
(frequency)
 Caucasian
rs759170 UK SZ
CTR		 0.18
0.17		 0.82
0.83		 13 (0.033)
38 (0.028)		 119 (0.301)
376 (0.280)		 264 (0.667)
928 (0.692)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   C-Allele G-Allele C/C
(frequency)		 C/G
(frequency)		 G/G
(frequency)
 Caucasian
rs3823585 UK SZ
CTR		 0.39
0.34		 0.61
0.66		 60 (0.152)
156 (0.116)		 188 (0.475)
603 (0.449)		 148 (0.374)
583 (0.434)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   C-Allele T-Allele C/C
(frequency)		 C/T
(frequency)		 T/T
(frequency)
 Caucasian
rs2110290 UK SZ
CTR		 0.33
0.31		 0.67
0.69		 44 (0.111)
126 (0.094)		 176 (0.444)
571 (0.425)		 176 (0.444)
645 (0.481)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   G-Allele A-Allele G/G
(frequency)		 G/A
(frequency)		 A/A
(frequency)
 Caucasian
rs759160 UK SZ
CTR		 0.20
0.24		 0.80
0.76		 16 (0.040)
74 (0.055)		 126 (0.318)
483 (0.360)		 254 (0.641)
785 (0.585)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   A-Allele C-Allele A/A
(frequency)		 A/C
(frequency)		 C/C
(frequency)
 Caucasian
rs6947594 UK SZ
CTR		 0.12
0.13		 0.88
0.87		 6 (0.015)
22 (0.016)		 84 (0.212)
302 (0.225)		 307 (0.773)
1017 (0.758)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   m-Allele M-Allele m/m
(frequency)		 m/M
(frequency)		 M/M
(frequency)
 Caucasian
rs2072454 UK SZ
CTR		 0.49
0.48		 0.51
0.52		 94 (0.237)
306 (0.228)		 198 (0.500)
670 (0.499)		 104 (0.263)
366 (0.273)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   A-Allele G-Allele A/A
(frequency)		 A/G
(frequency)		 G/G
(frequency)
 Caucasian
rs845551 UK SZ
CTR		 0.18
0.21		 0.82
0.79		 13 (0.033)
58 (0.043)		 116 (0.292)
442 (0.329)		 268 (0.675)
842 (0.627)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   C-Allele T-Allele C/C
(frequency)		 C/T
(frequency)		 T/T
(frequency)
 Caucasian
rs10241451 UK SZ
CTR		 0.22
0.24		 0.78
0.76		 20 (0.051)
76 (0.057)		 137 (0.346)
487 (0.363)		 239 (0.604)
779 (0.580)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   T-Allele C-Allele T/T
(frequency)		 T/C
(frequency)		 C/C
(frequency)
 Caucasian
rs2075107 UK SZ
CTR		 0.38
0.38		 0.62
0.62		 56 (0.141)
194 (0.145)		 186 (0.469)
632 (0.471)		 155 (0.390)
516 (0.385)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   A-Allele G-Allele A/A
(frequency)		 A/G
(frequency)		 G/G
(frequency)
 Caucasian
rs6970262 UK SZ
CTR		 0.40
0.39		 0.60
0.61		 63 (0.159)
202 (0.151)		 190 (0.479)
637 (0.475)		 144 (0.363)
503 (0.375)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   A-Allele G-Allele A/A
(frequency)		 A/G
(frequency)		 G/G
(frequency)
 Caucasian
rs2293348 UK SZ
CTR		 0.33
0.33		 0.67
0.67		 42 (0.106)
150 (0.112)		 174 (0.439)
597 (0.445)		 180 (0.455)
595 (0.443)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   G-Allele A-Allele G/G
(frequency)		 G/A
(frequency)		 A/A
(frequency)
 Caucasian
rs884225 UK SZ
CTR		 0.06
0.08		 0.94
0.92		 1 (0.003)
9 (0.007)		 44 (0.111)
204 (0.152)		 351 (0.886)
1128 (0.841)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   m-Allele M-Allele m/m
(frequency)		 m/M
(frequency)		 M/M
(frequency)
 Caucasian
rs4245566 UK SZ
CTR		 0.46
0.44		 0.54
0.56		 84 (0.212)
260 (0.194)		 197 (0.497)
661 (0.493)		 115 (0.290)
421 (0.314)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   T-Allele C-Allele T/T
(frequency)		 T/C
(frequency)		 C/C
(frequency)
 Caucasian
rs883117 UK SZ
CTR		 0.04
0.06		 0.96
0.94		 1 (0.003)
4 (0.003)		 30 (0.076)
146 (0.109)		 365 (0.922)
1191 (0.888)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   m-Allele M-Allele m/m
(frequency)		 m/M
(frequency)		 M/M
(frequency)
 Caucasian
rs6969564 UK SZ
CTR		 0.19
0.18		 0.81
0.82		 15 (0.038)
43 (0.032)		 124 (0.313)
394 (0.294)		 257 (0.649)
905 (0.674)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   A-Allele G-Allele A/A
(frequency)		 A/G
(frequency)		 G/G
(frequency)
 Caucasian
rs1525642 UK SZ
CTR		 0.20
0.20		 0.80
0.80		 15 (0.038)
54 (0.040)		 125 (0.316)
431 (0.321)		 256 (0.646)
857 (0.639)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.
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SZGene Stats
Studies: 1727
Genes: 1008
Polymorphisms: 8788
Meta-analyses: 287
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