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Polymorphism Details     
Back Search Methods Disclaimer Credits
 Study: Olsen, 2008
 Gene: HK1  (HKI; HXK1; HK1-ta; HK1-tb; HK1-tc)  Entrez Gene    View on AlzGene
 Protein: hexokinase 1  (glycolytic enzyme; brain form hexokinase)  ProteinLink
 Chromosome: 10   (View: 1  2  3  4  5  6  7  8  9  10  11  12  13  14  15  16  17  18  19  20  21  22  X  Y  MT)
 Status: Updated 8 May 2008
Meta-Analysis     Gene Overview
Total number of polymorphisms investigated by this study: 32

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   G-Allele C-Allele G/G
(frequency)		 G/C
(frequency)		 C/C
(frequency)
 Caucasian
rs10762288 Scandinavia SZ
CTR		 0.22
0.23		 0.78
0.77		 37 (0.048)
67 (0.053)		 263 (0.344)
451 (0.354)		 465 (0.608)
755 (0.593)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   T-Allele C-Allele T/T
(frequency)		 T/C
(frequency)		 C/C
(frequency)
 Caucasian
rs10823356 Scandinavia SZ
CTR		 0.35
0.38		 0.65
0.62		 94 (0.123)
184 (0.144)		 348 (0.455)
600 (0.471)		 323 (0.422)
490 (0.385)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   A-Allele T-Allele A/A
(frequency)		 A/T
(frequency)		 T/T
(frequency)
 Caucasian
rs10823357 Scandinavia SZ
CTR		 0.37
0.38		 0.63
0.62		 105 (0.137)
184 (0.144)		 357 (0.466)
600 (0.471)		 304 (0.397)
490 (0.385)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   A-Allele G-Allele A/A
(frequency)		 A/G
(frequency)		 G/G
(frequency)
 Caucasian
rs10998715 Scandinavia SZ
CTR		 0.02
0.02		 0.98
0.98		 0 (0.000)
1 (0.001)		 30 (0.039)
50 (0.039)		 735 (0.961)
1224 (0.960)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   A-Allele G-Allele A/A
(frequency)		 A/G
(frequency)		 G/G
(frequency)
 Caucasian
rs10998719 Scandinavia SZ
CTR		 0.12
0.12		 0.88
0.88		 11 (0.014)
18 (0.014)		 162 (0.212)
269 (0.211)		 592 (0.774)
987 (0.775)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   G-Allele T-Allele G/G
(frequency)		 G/T
(frequency)		 T/T
(frequency)
 Caucasian
rs10998724 Scandinavia SZ
CTR		 0.06
0.07		 0.94
0.93		 3 (0.004)
6 (0.005)		 86 (0.112)
166 (0.130)		 676 (0.884)
1102 (0.865)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   T-Allele G-Allele T/T
(frequency)		 T/G
(frequency)		 G/G
(frequency)
 Caucasian
rs10998726 Scandinavia SZ
CTR		 0.06
0.07		 0.94
0.93		 3 (0.004)
6 (0.005)		 86 (0.112)
166 (0.130)		 676 (0.884)
1102 (0.865)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   G-Allele C-Allele G/G
(frequency)		 G/C
(frequency)		 C/C
(frequency)
 Caucasian
rs1133189 Scandinavia SZ
CTR		 0.41
0.41		 0.59
0.59		 129 (0.169)
214 (0.168)		 370 (0.484)
616 (0.484)		 266 (0.348)
443 (0.348)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   G-Allele A-Allele G/G
(frequency)		 G/A
(frequency)		 A/A
(frequency)
 Caucasian
rs11596868 Scandinavia SZ
CTR		 0.03
0.03		 0.97
0.97		 1 (0.001)
1 (0.001)		 45 (0.059)
74 (0.058)		 720 (0.940)
1199 (0.941)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   T-Allele C-Allele T/T
(frequency)		 T/C
(frequency)		 C/C
(frequency)
 Caucasian
rs11598389 Scandinavia SZ
CTR		 0.05
0.06		 0.95
0.94		 2 (0.003)
5 (0.004)		 73 (0.095)
144 (0.113)		 690 (0.902)
1126 (0.883)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   T-Allele C-Allele T/T
(frequency)		 T/C
(frequency)		 C/C
(frequency)
 Caucasian
rs11599150 Scandinavia SZ
CTR		 0.04
0.04		 0.96
0.96		 1 (0.001)
2 (0.002)		 59 (0.077)
98 (0.077)		 705 (0.922)
1174 (0.922)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   T-Allele G-Allele T/T
(frequency)		 T/G
(frequency)		 G/G
(frequency)
 Caucasian
rs12220752 Scandinavia SZ
CTR		 0.08
0.08		 0.92
0.92		 5 (0.007)
8 (0.006)		 113 (0.148)
188 (0.148)		 647 (0.846)
1078 (0.846)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   G-Allele A-Allele G/G
(frequency)		 G/A
(frequency)		 A/A
(frequency)
 Caucasian
rs12355201 Scandinavia SZ
CTR		 0.39
0.38		 0.61
0.62		 116 (0.152)
184 (0.144)		 364 (0.476)
600 (0.471)		 285 (0.373)
490 (0.385)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   A-Allele G-Allele A/A
(frequency)		 A/G
(frequency)		 G/G
(frequency)
 Caucasian
rs12416320 Scandinavia SZ
CTR		 0.05
0.06		 0.95
0.94		 2 (0.003)
5 (0.004)		 73 (0.095)
144 (0.113)		 690 (0.902)
1126 (0.883)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   T-Allele C-Allele T/T
(frequency)		 T/C
(frequency)		 C/C
(frequency)
 Caucasian
rs12771121 Scandinavia SZ
CTR		 0.20
0.21		 0.80
0.79		 31 (0.040)
56 (0.044)		 245 (0.320)
423 (0.332)		 490 (0.640)
795 (0.624)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   T-Allele C-Allele T/T
(frequency)		 T/C
(frequency)		 C/C
(frequency)
 Caucasian
rs16926246 Scandinavia SZ
CTR		 0.12
0.13		 0.88
0.87		 11 (0.014)
22 (0.017)		 162 (0.212)
288 (0.226)		 592 (0.774)
964 (0.757)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   C-Allele T-Allele C/C
(frequency)		 C/T
(frequency)		 T/T
(frequency)
 Caucasian
rs16926292 Scandinavia SZ
CTR		 0.11
0.11		 0.89
0.89		 9 (0.012)
15 (0.012)		 150 (0.196)
249 (0.196)		 606 (0.792)
1009 (0.793)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   T-Allele C-Allele T/T
(frequency)		 T/C
(frequency)		 C/C
(frequency)
 Caucasian
rs2015803 Scandinavia SZ
CTR		 0.24
0.22		 0.76
0.78		 44 (0.058)
62 (0.049)		 279 (0.365)
437 (0.343)		 442 (0.578)
775 (0.608)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   G-Allele A-Allele G/G
(frequency)		 G/A
(frequency)		 A/A
(frequency)
 Caucasian
rs2084274 Scandinavia SZ
CTR		 0.48
0.50		 0.52
0.50		 176 (0.230)
319 (0.250)		 382 (0.499)
637 (0.500)		 207 (0.271)
319 (0.250)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   C-Allele A-Allele C/C
(frequency)		 C/A
(frequency)		 A/A
(frequency)
 Caucasian
rs4589168 Scandinavia SZ
CTR		 0.01
0.01		 0.99
0.99		 0 (0.000)
0 (0.000)		 15 (0.020)
25 (0.020)		 750 (0.980)
1249 (0.980)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   G-Allele T-Allele G/G
(frequency)		 G/T
(frequency)		 T/T
(frequency)
 Caucasian
rs4745982 Scandinavia SZ
CTR		 0.09
0.08		 0.91
0.92		 6 (0.008)
8 (0.006)		 125 (0.164)
188 (0.148)		 633 (0.829)
1078 (0.846)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   A-Allele G-Allele A/A
(frequency)		 A/G
(frequency)		 G/G
(frequency)
 Caucasian
rs4746846 Scandinavia SZ
CTR		 0.21
0.22		 0.79
0.78		 34 (0.044)
62 (0.049)		 254 (0.332)
437 (0.343)		 477 (0.624)
775 (0.608)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   G-Allele T-Allele G/G
(frequency)		 G/T
(frequency)		 T/T
(frequency)
 Caucasian
rs4746849 Scandinavia SZ
CTR		 0.18
0.20		 0.82
0.80		 25 (0.033)
51 (0.040)		 226 (0.295)
408 (0.320)		 514 (0.672)
815 (0.640)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   C-Allele T-Allele C/C
(frequency)		 C/T
(frequency)		 T/T
(frequency)
 Caucasian
rs7079157 Scandinavia SZ
CTR		 0.25
0.27		 0.75
0.73		 48 (0.063)
93 (0.073)		 287 (0.375)
502 (0.394)		 430 (0.562)
679 (0.533)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   G-Allele A-Allele G/G
(frequency)		 G/A
(frequency)		 A/A
(frequency)
 Caucasian
rs7081302 Scandinavia SZ
CTR		 0.03
0.03		 0.97
0.97		 1 (0.001)
1 (0.001)		 45 (0.059)
74 (0.058)		 720 (0.940)
1199 (0.941)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   G-Allele A-Allele G/G
(frequency)		 G/A
(frequency)		 A/A
(frequency)
 Caucasian
rs748235 Scandinavia SZ
CTR		 0.22
0.22		 0.78
0.78		 37 (0.048)
62 (0.049)		 263 (0.344)
437 (0.343)		 465 (0.608)
775 (0.608)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   G-Allele A-Allele G/G
(frequency)		 G/A
(frequency)		 A/A
(frequency)
 Caucasian
rs749105 Scandinavia SZ
CTR		 0.31
0.31		 0.69
0.69		 74 (0.097)
122 (0.096)		 327 (0.427)
545 (0.428)		 364 (0.476)
607 (0.476)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   G-Allele T-Allele G/G
(frequency)		 G/T
(frequency)		 T/T
(frequency)
 Caucasian
rs749106 Scandinavia SZ
CTR		 0.11
0.11		 0.89
0.89		 9 (0.012)
15 (0.012)		 150 (0.196)
249 (0.196)		 606 (0.792)
1009 (0.793)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   A-Allele G-Allele A/A
(frequency)		 A/G
(frequency)		 G/G
(frequency)
 Caucasian
rs7898060 Scandinavia SZ
CTR		 0.15
0.15		 0.85
0.85		 17 (0.022)
29 (0.023)		 195 (0.255)
325 (0.255)		 553 (0.723)
920 (0.722)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   C-Allele A-Allele C/C
(frequency)		 C/A
(frequency)		 A/A
(frequency)
 Caucasian
rs7902486 Scandinavia SZ
CTR		 0.05
0.06		 0.95
0.94		 2 (0.003)
5 (0.004)		 73 (0.095)
144 (0.113)		 690 (0.902)
1126 (0.883)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   A-Allele G-Allele A/A
(frequency)		 A/G
(frequency)		 G/G
(frequency)
 Caucasian
rs7909192 Scandinavia SZ
CTR		 0.36
0.36		 0.64
0.64		 99 (0.129)
165 (0.130)		 353 (0.461)
587 (0.461)		 313 (0.409)
522 (0.410)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   T-Allele C-Allele T/T
(frequency)		 T/C
(frequency)		 C/C
(frequency)
 Caucasian
rs7921170 Scandinavia SZ
CTR		 0.05
0.05		 0.95
0.95		 2 (0.003)
3 (0.002)		 73 (0.095)
121 (0.095)		 690 (0.902)
1150 (0.903)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.
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