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Meta-Analysis of All Published SZ Association Studies (Case-Control Only) rs10503929
Back Search Methods Disclaimer Credits
 Polymorphism: rs10503929
 Gene: NRG1  (GGF; HGL; HRG; NDF; ARIA; GGF2; HRG1; HRGA; SMDF)  Entrez Gene    View on AlzGene
 Protein: neuregulin 1  (glial growth factor; neu differentiation factor; sensory and motor neuron derived factor; heregulin, alpha (45kD, ERBB2 p185-activator))  ProteinLink
 Chromosome: 8   (View: 1  2  3  4  5  6  7  8  9  10  11  12  13  14  15  16  17  18  19  20  21  22  X  Y  MT)
 Status: Updated 23 November 2010
Gene Overview
 Polymorphism:
1) Summary of Allele and Genotype Distribution of all Published Association Studies (by Ethnic Group)
      Alleles Genotypes
  # Case-Control
Samples
  C-Allele
(frequency)
T-Allele
(frequency)
C/C
(frequency)
C/T
(frequency)
T/T
(frequency)
 Caucasian 3 SZ
CTR
0.17
0.19
0.83
0.81
87 (0.029)
148 (0.037)
861 (0.285)
1240 (0.310)
2068 (0.686)
2607 (0.653)
 Other/Mixed 1 SZ
CTR
0.09
0.10
0.91
0.90
2 (0.008)
2 (0.011)
41 (0.171)
34 (0.183)
197 (0.821)
150 (0.806)
Total 4 SZ
CTR
0.17
0.19
0.83
0.81
89 (0.027)
150 (0.036)
902 (0.277)
1274 (0.305)
2265 (0.696)
2757 (0.659)

Meta-Analysis Methods      * New * Cumulative Meta-analysis
2) Forest plot for polymorphism  rs10503929

Please also see disclaimer for more information on these meta-analyses.


Meta-analyses have not been performed on the following polymorphisms since they lack published genotype data in at least four independent case-control samples, or the published genotype data was otherwise not eligible for inclusion (see methods for details):

225C17-4
244L21-8557
29H12-1
29H12-121L21
29H12-7320
317J8-1
317J8-2
317J8-2123
317J8-4858
420M9-1
420M9-116I12
420M9-1395
420M9-3663
420Mp-116I12
450K14-72458
473C15-439
473C15-533
478B14-642
478B14-848
487-2
72H22-1
72H22-36
82H10-79B8
D8S1110
D8S1477
D8S1711
D8S1769
D8S1770
D8S1810
D8S1820
NRG1_exon11G/T
NRG1_V266L (exon 11)
NRG1NEWNS
rs10081436
rs10087212
rs10087939
rs10087952
rs10091429
rs10092347
rs10093464
rs10095556
rs10095694
rs10096573
rs10096770
rs10098373
rs10098433
rs10098998
rs10099542
rs10103255
rs10103750
rs10103930
rs10103976
rs10105300
rs10107065
rs10113797
rs1023911
rs10503887
rs10503888
rs10503889
rs10503894
rs10503897
rs10503899
rs10503900
rs10503903
rs10503904
rs10503905
rs10503907
rs10503913
rs10503914
rs10503915
rs10503917
rs10503919
rs10503923
rs10503932
rs10691392
rs10712721
rs10808322
rs1081062
rs10954809
rs10954810
rs10954811
rs10954818
rs10954821
rs10954822
rs10954842
rs10954855
rs10954864
rs1158105
rs11776959
rs11780520
rs11782374
rs11782671
rs11783236
rs11989919
rs11993157
rs11998176
rs12155594
rs12541452
rs12546380
rs12547331
rs12547858
rs12549243
rs12674974
rs12677942
rs12679454
rs12680804
rs12682268
rs12682592
rs13257203
rs13259346
rs13260545
rs13263208 (hCV2061466)
rs13268778
rs13270788
rs13274954
rs13277456
rs13279876
rs13439182
rs1351510
rs1354334
rs1354335
rs1354336
rs1381866
rs1381871
rs1383887
rs1383890
rs1383895
rs1383959
rs1383960
rs1383961
rs1383964
rs1386437
rs1386439
rs1386440
rs1393952
rs1462893
rs1462906
rs1473438
rs1481615
rs1481617
rs1481619
rs1481625
rs1481628
rs1481731
rs1481747
rs1481748
rs1481756
rs1481758
rs1481762
rs1487141
rs1487152
rs1503486
rs1503487
rs1503488
rs1503489
rs1503491
rs1503497
rs1531746
rs1545961
rs1557800
rs1566778
rs1599677
rs167858
rs167859
rs16878243
rs16878410
rs16878421
rs16878972
rs16879014
rs16879147
rs16879153
rs16879364
rs16879425
rs16879463
rs16879773
rs16879886
rs16879922
rs16879927
rs1699128
rs17601950
rs17602316
rs17646307
rs17669617
rs17671089
rs17690742
rs17695276
rs17716113
rs17722883
rs17731664
rs1825133
rs1948097
rs1948098
rs2062055
rs2062057
rs2062818
rs2129533
rs2134619
rs2189145
rs2200033
rs2202262
rs227766
rs2345991
rs2346771
rs2347499
rs2347501
rs2439273
rs2439279
rs2439281
rs2439282
rs2439284
rs2439286
rs2439300
rs2439305
rs2439306
rs2439311
rs2439319
rs2439321
rs2466046
rs2466048
rs2466049
rs2466052
rs2466059
rs2466060
rs2466061
rs2466062
rs2466064
rs2466071
rs2466084
rs2466094
rs2466098
rs2683768
rs2881272
rs2881472
rs2881651
rs2919375
rs2919377
rs2919378
rs2919379
rs2919381
rs2919382
rs2919385
rs2919390
rs2975498
rs2976515
rs2976525
rs2976532
rs327325
rs327329
rs327386
rs327412
rs327417
rs35641374 (hCV25632294)
rs371771
rs3735774
rs3735776
rs3735781
rs3735782
rs3751929
rs3757928
rs3757929
rs3757930
rs3757931
rs3757933
rs3757934
rs3802158
rs3802159
rs3808368
rs383632
rs3847131
rs385396
rs41404249
rs4147430
rs4236709
rs4236710
rs4262285
rs4268090
rs4281084
rs4298458
rs4316112
rs4317533
rs432063
rs4352805
rs4360253
rs4373483
rs4403369
rs4445183
rs4452759
rs4457297
rs4458836
rs4476964
rs449951
rs4501543
rs4512342
rs4513929
rs4521723
rs4535704
rs4559204
rs4560751
rs4566990
rs4590397
rs4733094
rs4733124
rs4733125
rs4733130
rs4733132
rs4733263
rs4733267
rs4733269
rs4733271
rs4733288
rs4733295
rs4733298
rs4733299
rs4733302
rs4733306
rs4733342
rs4733346
rs4733348
rs4733361
rs553950
rs5890668
rs6150532
rs6468061
rs6468085
rs6468095
rs6468099
rs6468108
rs6468111
rs6468118
rs6468121
rs6468122
rs6651144
rs6983573
rs6985581
rs6986716
rs6987310
rs6989777
rs6989889
rs6992010
rs6992642
rs6992907
rs6994992 (SNP8NRG243177)
rs6995261
rs6996203
rs6997612
rs6999624
rs6999977
rs7000590
rs7000656
rs7000831
rs7001060
rs7002063
rs7002832
rs7002924
rs7003184
rs7005124
rs7005288
rs7007436
rs7007662
rs7010701
rs7011088
rs7013361
rs7014221
rs7014410
rs7014762
rs7015249
rs7015770
rs7016691
rs7017348
rs701955
rs716144
rs723811
rs726908
rs733230
rs7463426
rs756266
rs763551
rs763552
rs763553
rs764059
rs776382
rs776385
rs776398
rs7812662
rs7815480
rs7818040
rs7818326
rs7818821
rs7819063
rs7820838
rs7821017
rs7822564
rs7822917
rs7823899
rs7824097
rs7824399
rs7825588
rs7826814
rs7827456
rs7827460
rs7827584
rs7829669
rs7834206
rs7835688
rs7839411
rs7841677
rs7843578
rs7845510
rs796549
rs800501
rs901561
rs9297186
rs9297189
rs9297195
rs9297196
rs939077
rs9642729
rs967205
rs970412
rs970413
rs970997
rs983944
rs9886497
rs9918832
rs-GSK11536598
rs-GSK11536599
rs-GSK11536600
S8S1765
S8S4792
SNP8NR221533
SNP8NRG103492
SNP8NRG157556
SNP8NRG221533
SNP8NRG222662
SNP8NRG224932
SNP8NRG243177
SNP8NRG444511
SNP8NRGd131E1006
TSC0707270
TSC0707290

SZGene Recent Updates
SZGene Stats
Studies: 1727
Genes: 1008
Polymorphisms: 8788
Meta-analyses: 287
ALSGene
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MSGene
PDGene
SZGene
An up-to-date collection of all published genetic association studies.
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