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Meta-Analysis of All Published SZ Association Studies (Case-Control Only) SLC6A3_40bpVNTR
Back Search Methods Disclaimer Credits
 Polymorphism: SLC6A3_40bpVNTR (3'UTR)
 Gene: SLC6A3  (DAT; DAT1)  Entrez Gene    View on AlzGene   View on PDGene
 Protein: solute carrier family 6 (neurotransmitter transporter, dopamine), member 3  (dopamine transporter)  ProteinLink
 Chromosome: 5   (View: 1  2  3  4  5  6  7  8  9  10  11  12  13  14  15  16  17  18  19  20  21  22  X  Y  MT)
 Status: Updated 22 October 2010
Gene Overview
 Polymorphism:
1) Summary of Allele and Genotype Distribution of all Published Association Studies (by Ethnic Group)
      Alleles Genotypes
  # Case-Control
Samples
  9-Allele
(frequency)
10-Allele
(frequency)
rare-Allele
(frequency)
9/9
(frequency)
9/10
(frequency)
10/10
(frequency)
9/rare
(frequency)
10/rare
(frequency)
rare/rare
(frequency)
 Caucasian 8 SZ
CTR
0.28
0.30
0.70
0.68
0.02
0.02
92 (0.083)
124 (0.096)
423 (0.383)
514 (0.399)
548 (0.496)
605 (0.470)
8 (0.007)
12 (0.009)
26 (0.024)
31 (0.024)
7 (0.006)
1 (0.001)
 Asian 6 SZ
CTR
0.05
0.06
0.91
0.92
0.04
0.03
3 (0.003)
4 (0.005)
83 (0.089)
89 (0.101)
780 (0.834)
737 (0.838)
1 (0.001)
0 (0.000)
67 (0.072)
48 (0.055)
1 (0.001)
2 (0.002)
 Other/Mixed 1 SZ
CTR
0.23
0.21
0.75
0.79
0.02
0.00
2 (0.071)
1 (0.032)
8 (0.286)
11 (0.355)
17 (0.607)
19 (0.613)
1 (0.036)
0 (0.000)
0 (0.000)
0 (0.000)
0 (0.000)
0 (0.000)
Total 15 SZ
CTR
0.17
0.20
0.80
0.78
0.03
0.02
97 (0.047)
129 (0.059)
514 (0.249)
614 (0.279)
1345 (0.651)
1361 (0.619)
10 (0.005)
12 (0.005)
93 (0.045)
79 (0.036)
8 (0.004)
3 (0.001)

Meta-Analysis Methods      * New * Cumulative Meta-analysis
2) Forest plot for polymorphism SLC6A3_40bpVNTR (3'UTR)

Please also see disclaimer for more information on these meta-analyses.


Meta-analyses have not been performed on the following polymorphisms since they lack published genotype data in at least four independent case-control samples, or the published genotype data was otherwise not eligible for inclusion (see methods for details):

D5S2005
D5S406
rs10052016
rs11133767
rs11564758
rs11564772
rs12516948
rs2042449
rs2078247
rs2270912
rs2550947
rs2550956
rs2617596
rs2617605
rs2652511
rs27048
rs27072
rs27074
rs2735917
rs2975226
rs2975226 (-67A/T)
rs2975292
rs37022
rs3756450
rs40184
rs403636
rs420422
rs429699
rs456082
rs460000
rs460700
rs463379
rs464049
rs4975636
rs6347
rs6350
rs6413429
rs6869645
SLC6A3_839C/T
SLC6A3_unknown-poly

SZGene Recent Updates
SZGene Stats
Studies: 1727
Genes: 1008
Polymorphisms: 8788
Meta-analyses: 287
ALSGene
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MSGene
PDGene
SZGene
An up-to-date collection of all published genetic association studies.
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