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Printable version
Meta-Analysis of All Published SZ Association Studies (Case-Control Only)
SLC6A3_40bpVNTR
Polymorphism:
SLC6A3_40bpVNTR (3'UTR)
Gene:
SLC6A3
(DAT; DAT1)
View on AlzGene
View on PDGene
Protein:
solute carrier family 6 (neurotransmitter transporter, dopamine), member 3
(dopamine transporter)
Chromosome:
5
(View:
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
X
Y
MT
)
Status:
Updated 22 October 2010
Polymorphism:
SLC6A3_40bpVNTR
1) Summary of Allele and Genotype Distribution of all Published Association Studies (by Ethnic Group)
Alleles
Genotypes
# Case-Control
Samples
9-Allele
(frequency)
10-Allele
(frequency)
rare-Allele
(frequency)
9/9
(frequency)
9/10
(frequency)
10/10
(frequency)
9/rare
(frequency)
10/rare
(frequency)
rare/rare
(frequency)
Caucasian
8
SZ
CTR
0.28
0.30
0.70
0.68
0.02
0.02
92 (0.083)
124 (0.096)
423 (0.383)
514 (0.399)
548 (0.496)
605 (0.470)
8 (0.007)
12 (0.009)
26 (0.024)
31 (0.024)
7 (0.006)
1 (0.001)
Asian
6
SZ
CTR
0.05
0.06
0.91
0.92
0.04
0.03
3 (0.003)
4 (0.005)
83 (0.089)
89 (0.101)
780 (0.834)
737 (0.838)
1 (0.001)
0 (0.000)
67 (0.072)
48 (0.055)
1 (0.001)
2 (0.002)
Other/Mixed
1
SZ
CTR
0.23
0.21
0.75
0.79
0.02
0.00
2 (0.071)
1 (0.032)
8 (0.286)
11 (0.355)
17 (0.607)
19 (0.613)
1 (0.036)
0 (0.000)
0 (0.000)
0 (0.000)
0 (0.000)
0 (0.000)
Total
15
SZ
CTR
0.17
0.20
0.80
0.78
0.03
0.02
97 (0.047)
129 (0.059)
514 (0.249)
614 (0.279)
1345 (0.651)
1361 (0.619)
10 (0.005)
12 (0.005)
93 (0.045)
79 (0.036)
8 (0.004)
3 (0.001)
Meta-Analysis Methods
* New *
Cumulative Meta-analysis
2) Forest plot for polymorphism
SLC6A3_40bpVNTR (3'UTR)
Please also
see disclaimer
for more information on these meta-analyses.
Meta-analyses have not been performed on the following polymorphisms since they lack published genotype data in at least four independent case-control samples, or the published genotype data was otherwise not eligible for inclusion (see
methods
for details):
D5S2005
D5S406
rs10052016
rs11133767
rs11564758
rs11564772
rs12516948
rs2042449
rs2078247
rs2270912
rs2550947
rs2550956
rs2617596
rs2617605
rs2652511
rs27048
rs27072
rs27074
rs2735917
rs2975226
rs2975226 (-67A/T)
rs2975292
rs37022
rs3756450
rs40184
rs403636
rs420422
rs429699
rs456082
rs460000
rs460700
rs463379
rs464049
rs4975636
rs6347
rs6350
rs6413429
rs6869645
SLC6A3_–839C/T
SLC6A3_unknown-poly
SZGene Recent Updates
SZGene Stats
Studies: 1727
Genes: 1008
Polymorphisms: 8788
Meta-analyses: 287
ALSGene
AlzGene
MSGene
PDGene
SZGene
An up-to-date collection of all published genetic association studies.
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