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Meta-Analysis of All Published SZ Association Studies (Case-Control Only) rs6277
Back Search Methods Disclaimer Credits
 Polymorphism: rs6277 (Pro319Pro)
 Gene: DRD2  (D2R; D2DR)  Entrez Gene    View on PDGene
 Protein: dopamine receptor D2  (seven transmembrane helix receptor)  ProteinLink
 Chromosome: 11   (View: 1  2  3  4  5  6  7  8  9  10  11  12  13  14  15  16  17  18  19  20  21  22  X  Y  MT)
 Status: Updated 21 October 2010
Gene Overview
 Polymorphism:
1) Summary of Allele and Genotype Distribution of all Published Association Studies (by Ethnic Group)
      Alleles Genotypes
  # Case-Control
Samples
  C-Allele
(frequency)
T-Allele
(frequency)
C/C
(frequency)
C/T
(frequency)
T/T
(frequency)
 Caucasian 8 SZ
CTR
0.50
0.45
0.50
0.55
786 (0.249)
831 (0.210)
1564 (0.496)
1923 (0.486)
806 (0.255)
1206 (0.305)
 Asian 1 SZ
CTR
0.93
0.96
0.07
0.05
366 (0.869)
368 (0.913)
52 (0.124)
34 (0.084)
3 (0.007)
1 (0.002)
 Other/Mixed 1 SZ
CTR
0.63
0.60
0.37
0.40
104 (0.409)
76 (0.338)
112 (0.441)
120 (0.533)
38 (0.150)
29 (0.129)
Total 10 SZ
CTR
0.55
0.50
0.45
0.50
1256 (0.328)
1275 (0.278)
1728 (0.451)
2077 (0.453)
847 (0.221)
1236 (0.269)

Meta-Analysis Methods      * New * Cumulative Meta-analysis
2) Forest plot for polymorphism  rs6277 (Pro319Pro)

Please also see disclaimer for more information on these meta-analyses.


Meta-analyses have not been performed on the following polymorphisms since they lack published genotype data in at least four independent case-control samples, or the published genotype data was otherwise not eligible for inclusion (see methods for details):

D11S3179
DRD2_-241A/G
DRD2_2bpSTR (GTn)
DRD2_2bpSTR (GTn)
RH27315 (STR)
rs1076560
rs1076563
rs1079594
rs1079595
rs1079596
rs1079727
rs10891552
rs10891556
rs1107162
rs1110977
rs11214606
rs11214613
rs1124491
rs1124492
rs11608185
rs12364283
rs12422191
rs12574471
rs12800853
rs12808482
rs1554929
rs17115583
rs17529477
rs1799978
rs1800496
rs1800498 (Taq1-D)
rs2075652
rs2075654
rs2234689
rs2234690
rs2242592
rs2283265
rs2440390
rs2511521
rs2587549
rs2734833
rs2734837
rs2734838
rs2734841
rs4245147
rs4245148
rs4274224
rs4350392
rs4436578
rs4460839
rs4581480
rs4586205
rs4587762
rs4648318
rs4648319
rs4936271
rs4938019
rs6278
rs6279
rs7110440
rs7116768
rs7122454
rs7125415
rs7131056
rs7350522

SZGene Recent Updates
SZGene Stats
Studies: 1727
Genes: 1008
Polymorphisms: 8788
Meta-analyses: 287
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