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Polymorphism Details     
Back Search Methods Disclaimer Credits
 Study: Jungerius, 2007
 Gene: ERBB4  (HER4; p180erbB4)  Entrez Gene
 Protein: v-erb-a erythroblastic leukemia viral oncogene homolog 4  (receptor tyrosine-protein kinase erbB-4; tyrosine kinase-type cell surface receptor HER4; avian erythroblastic leukemia viral (v-erb-b2) oncogene homolog 4; v-erb-a avian erythroblastic leukemia viral oncogene homolog-like 4)  ProteinLink
 Chromosome: 2   (View: 1  2  3  4  5  6  7  8  9  10  11  12  13  14  15  16  17  18  19  20  21  22  X  Y  MT)
 Status: Updated 21 October 2010
Meta-Analysis     Gene Overview
Total number of polymorphisms investigated by this study: 24

Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)		 Population   G-Allele C-Allele G/G
(frequency)		 G/C
(frequency)		 C/C
(frequency)
 Caucasian
rs1384292 Netherlands SZ
CTR		 -
-		 -
-		 0 (-)
0 (-)		 0 (-)
0 (-)		 0 (-)
0 (-)
(-) :  Either no data provided, or data otherwise not eligible for inclusion (see methods for details).

Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)		 Population   C-Allele T-Allele C/C
(frequency)		 C/T
(frequency)		 T/T
(frequency)
 Caucasian
rs1482381 Netherlands SZ
CTR		 0.17
0.17		 0.83
0.83		 9 (0.029)
16 (0.031)		 89 (0.287)
149 (0.286)		 212 (0.684)
356 (0.683)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)		 Population   m-Allele M-Allele m/m
(frequency)		 m/M
(frequency)		 M/M
(frequency)
 Caucasian
rs1851185 Netherlands SZ
CTR		 0.21
0.21		 0.79
0.79		 14 (0.045)
24 (0.046)		 103 (0.332)
175 (0.337)		 193 (0.623)
321 (0.617)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)		 Population   T-Allele C-Allele T/T
(frequency)		 T/C
(frequency)		 C/C
(frequency)
 Caucasian
rs6725181 Netherlands SZ
CTR		 0.09
0.09		 0.91
0.91		 2 (0.006)
4 (0.008)		 49 (0.159)
82 (0.158)		 258 (0.835)
434 (0.835)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)		 Population   C-Allele T-Allele C/C
(frequency)		 C/T
(frequency)		 T/T
(frequency)
 Caucasian
rs6745717 Netherlands SZ
CTR		 0.16
0.18		 0.84
0.82		 8 (0.026)
17 (0.033)		 84 (0.271)
153 (0.294)		 218 (0.703)
350 (0.673)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)		 Population   C-Allele T-Allele C/C
(frequency)		 C/T
(frequency)		 T/T
(frequency)
 Caucasian
rs3791702 Netherlands SZ
CTR		 0.29
0.29		 0.71
0.71		 27 (0.087)
43 (0.083)		 128 (0.414)
213 (0.409)		 154 (0.498)
265 (0.509)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)		 Population   G-Allele T-Allele G/G
(frequency)		 G/T
(frequency)		 T/T
(frequency)
 Caucasian
rs10497947 Netherlands SZ
CTR		 0.21
0.25		 0.79
0.75		 14 (0.045)
32 (0.062)		 104 (0.337)
193 (0.371)		 191 (0.618)
295 (0.567)


Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   A-Allele G-Allele A/A
(frequency)		 A/G
(frequency)		 G/G
(frequency)
 Caucasian
rs7588431 Netherlands SZ
CTR		 0.44
0.38		 0.56
0.62		 59 (0.190)
76 (0.146)		 152 (0.490)
246 (0.473)		 99 (0.319)
198 (0.381)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   C-Allele T-Allele C/C
(frequency)		 C/T
(frequency)		 T/T
(frequency)
 Caucasian
rs6435659 Netherlands SZ
CTR		 0.44
0.49		 0.56
0.51		 60 (0.194)
125 (0.241)		 153 (0.494)
259 (0.499)		 97 (0.313)
135 (0.260)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   C-Allele G-Allele C/C
(frequency)		 C/G
(frequency)		 G/G
(frequency)
 Caucasian
rs10932390 Netherlands SZ
CTR		 0.17
0.15		 0.83
0.85		 9 (0.029)
11 (0.021)		 88 (0.284)
130 (0.250)		 213 (0.687)
378 (0.728)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   T-Allele G-Allele T/T
(frequency)		 T/G
(frequency)		 G/G
(frequency)
 Caucasian
rs1851194 Netherlands SZ
CTR		 0.10
0.12		 0.90
0.88		 3 (0.010)
8 (0.015)		 57 (0.184)
111 (0.213)		 250 (0.806)
401 (0.771)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   G-Allele C-Allele G/G
(frequency)		 G/C
(frequency)		 C/C
(frequency)
 Caucasian
rs1836720 Netherlands SZ
CTR		 0.38
0.35		 0.62
0.65		 44 (0.142)
63 (0.121)		 145 (0.469)
236 (0.455)		 120 (0.388)
220 (0.424)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   A-Allele T-Allele A/A
(frequency)		 A/T
(frequency)		 T/T
(frequency)
 Caucasian
rs1976834 Netherlands SZ
CTR		 0.14
0.16		 0.86
0.84		 6 (0.019)
14 (0.027)		 76 (0.245)
141 (0.271)		 228 (0.735)
366 (0.702)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   T-Allele C-Allele T/T
(frequency)		 T/C
(frequency)		 C/C
(frequency)
 Caucasian
rs6435660 Netherlands SZ
CTR		 0.42
0.40		 0.58
0.60		 55 (0.177)
81 (0.156)		 151 (0.486)
249 (0.479)		 105 (0.338)
190 (0.365)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   A-Allele G-Allele A/A
(frequency)		 A/G
(frequency)		 G/G
(frequency)
 Caucasian
rs6706010 Netherlands SZ
CTR		 0.19
0.18		 0.81
0.82		 11 (0.036)
16 (0.031)		 96 (0.311)
150 (0.289)		 202 (0.654)
353 (0.680)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   T-Allele C-Allele T/T
(frequency)		 T/C
(frequency)		 C/C
(frequency)
 Caucasian
rs4132462 Netherlands SZ
CTR		 0.28
0.30		 0.72
0.70		 24 (0.078)
46 (0.088)		 124 (0.401)
217 (0.417)		 161 (0.521)
258 (0.495)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   C-Allele A-Allele C/C
(frequency)		 C/A
(frequency)		 A/A
(frequency)
 Caucasian
rs1816532 Netherlands SZ
CTR		 0.28
0.30		 0.72
0.70		 25 (0.081)
47 (0.091)		 126 (0.408)
219 (0.422)		 158 (0.511)
253 (0.487)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   A-Allele G-Allele A/A
(frequency)		 A/G
(frequency)		 G/G
(frequency)
 Caucasian
rs7425448 Netherlands SZ
CTR		 0.16
0.18		 0.84
0.82		 8 (0.026)
16 (0.031)		 85 (0.275)
151 (0.290)		 216 (0.699)
353 (0.679)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   G-Allele A-Allele G/G
(frequency)		 G/A
(frequency)		 A/A
(frequency)
 Caucasian
rs2371476 Netherlands SZ
CTR		 0.45
0.46		 0.55
0.54		 62 (0.200)
109 (0.210)		 153 (0.494)
258 (0.496)		 95 (0.306)
153 (0.294)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   G-Allele A-Allele G/G
(frequency)		 G/A
(frequency)		 A/A
(frequency)
 Caucasian
rs6719664 Netherlands SZ
CTR		 0.10
0.10		 0.90
0.90		 3 (0.010)
5 (0.010)		 58 (0.188)
92 (0.177)		 248 (0.803)
422 (0.813)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   T-Allele C-Allele T/T
(frequency)		 T/C
(frequency)		 C/C
(frequency)
 Caucasian
rs839519 Netherlands SZ
CTR		 0.16
0.16		 0.84
0.84		 8 (0.026)
13 (0.025)		 85 (0.275)
137 (0.264)		 216 (0.699)
369 (0.711)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   C-Allele T-Allele C/C
(frequency)		 C/T
(frequency)		 T/T
(frequency)
 Caucasian
rs6731471 Netherlands SZ
CTR		 0.33
0.32		 0.67
0.68		 34 (0.110)
55 (0.106)		 138 (0.445)
228 (0.438)		 138 (0.445)
238 (0.457)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   A-Allele G-Allele A/A
(frequency)		 A/G
(frequency)		 G/G
(frequency)
 Caucasian
rs839533 Netherlands SZ
CTR		 0.17
0.17		 0.83
0.83		 9 (0.029)
15 (0.029)		 87 (0.281)
147 (0.284)		 214 (0.690)
356 (0.687)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   G-Allele C-Allele G/G
(frequency)		 G/C
(frequency)		 C/C
(frequency)
 Caucasian
rs3923755 Netherlands SZ
CTR		 0.44
0.44		 0.56
0.56		 61 (0.196)
101 (0.194)		 153 (0.492)
256 (0.492)		 97 (0.312)
163 (0.313)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.
SZGene Recent Updates
SZGene Stats
Studies: 1727
Genes: 1008
Polymorphisms: 8788
Meta-analyses: 287
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