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Printable
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Polymorphism Details
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Gene: |
ERBB4
(HER4; p180erbB4)
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Protein: |
v-erb-a erythroblastic leukemia viral oncogene homolog 4
(receptor tyrosine-protein kinase erbB-4; tyrosine kinase-type cell surface receptor HER4; avian erythroblastic leukemia viral (v-erb-b2) oncogene homolog 4; v-erb-a avian erythroblastic leukemia viral oncogene homolog-like 4)
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Status: |
Updated 21 October 2010
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Total number of polymorphisms investigated by this study: 28 |
Case-Control Studies (by ethnic group) |
|
Genotypes |
Polymorphism ID# (Link to NCBI) |
Population |
|
m-Allele |
M-Allele |
m/m (frequency) |
m/M (frequency) |
M/M (frequency) |
Caucasian |
ERBB4_3228A>G
|
Ireland |
SZ CTR |
- - |
- - |
0 (-) 0 (-) |
0 (-) 0 (-) |
0 (-) 0 (-) |
ERBB4_3228A>G
|
UK (Cardiff) |
SZ CTR |
0.35 0.33 |
0.65 0.67 |
45 (0.122) 40 (0.109) |
167 (0.454) 163 (0.443) |
156 (0.424) 165 (0.448) |
(-) : Either no data provided, or data otherwise not eligible for inclusion (see methods for details).
Case-Control Studies (by ethnic group) |
|
Genotypes |
Polymorphism ID# (Link to NCBI) |
Population |
|
m-Allele |
M-Allele |
m/m (frequency) |
m/M (frequency) |
M/M (frequency) |
Caucasian |
ERBB4_IVS10+60C>T
|
UK (Cardiff) |
SZ CTR |
0.45 0.45 |
0.55 0.55 |
75 (0.204) 75 (0.204) |
182 (0.495) 182 (0.495) |
111 (0.302) 111 (0.302) |
ERBB4_IVS10+60C>T
|
Ireland |
SZ CTR |
- - |
- - |
0 (-) 0 (-) |
0 (-) 0 (-) |
0 (-) 0 (-) |
Case-Control Studies (by ethnic group) |
|
Genotypes |
Polymorphism ID# (Link to NCBI) |
Population |
|
m-Allele |
M-Allele |
m/m (frequency) |
m/M (frequency) |
M/M (frequency) |
Caucasian |
ERBB4_IVS12-15C>T
|
Ireland |
SZ CTR |
- - |
- - |
0 (-) 0 (-) |
0 (-) 0 (-) |
0 (-) 0 (-) |
ERBB4_IVS12-15C>T
|
UK (Cardiff full I) |
SZ CTR |
- - |
- - |
0 (-) 0 (-) |
0 (-) 0 (-) |
0 (-) 0 (-) |
ERBB4_IVS12-15C>T
|
Overlaps with Norton, 2006 UK (Cardiff full I) |
SZ CTR |
- - |
- - |
0 (-) 0 (-) |
0 (-) 0 (-) |
0 (-) 0 (-) |
(-) : Either no data provided, or data otherwise not eligible for inclusion (see methods for details).
Case-Control Studies (by ethnic group) |
|
Genotypes |
Polymorphism ID# (Link to NCBI) |
Population |
|
m-Allele |
M-Allele |
m/m (frequency) |
m/M (frequency) |
M/M (frequency) |
Caucasian |
ERBB4_IVS16+23T>C
|
Ireland |
SZ CTR |
- - |
- - |
0 (-) 0 (-) |
0 (-) 0 (-) |
0 (-) 0 (-) |
ERBB4_IVS16+23T>C
|
UK (Cardiff) |
SZ CTR |
0.07 0.07 |
0.93 0.93 |
2 (0.005) 2 (0.005) |
48 (0.130) 48 (0.130) |
318 (0.864) 318 (0.864) |
(-) : Either no data provided, or data otherwise not eligible for inclusion (see methods for details).
Case-Control Studies (by ethnic group) |
|
Genotypes |
Polymorphism ID# (Link to NCBI) |
Population |
|
m-Allele |
M-Allele |
m/m (frequency) |
m/M (frequency) |
M/M (frequency) |
Caucasian |
ERBB4_IVS16-24[A]
|
UK (Cardiff) |
SZ CTR |
0.09 0.10 |
0.91 0.90 |
3 (0.008) 4 (0.011) |
60 (0.163) 66 (0.179) |
305 (0.829) 298 (0.810) |
ERBB4_IVS16-24[A]
|
Ireland |
SZ CTR |
- - |
- - |
0 (-) 0 (-) |
0 (-) 0 (-) |
0 (-) 0 (-) |
Case-Control Studies (by ethnic group) |
|
Genotypes |
Polymorphism ID# (Link to NCBI) |
Population |
|
m-Allele |
M-Allele |
m/m (frequency) |
m/M (frequency) |
M/M (frequency) |
Caucasian |
ERBB4_IVS17-102[G]
|
Ireland |
SZ CTR |
- - |
- - |
0 (-) 0 (-) |
0 (-) 0 (-) |
0 (-) 0 (-) |
ERBB4_IVS17-102[G]
|
UK (Cardiff) |
SZ CTR |
0.10 0.09 |
0.90 0.91 |
4 (0.011) 3 (0.008) |
66 (0.179) 60 (0.163) |
298 (0.810) 305 (0.829) |
(-) : Either no data provided, or data otherwise not eligible for inclusion (see methods for details).
Case-Control Studies (by ethnic group) |
|
Genotypes |
Polymorphism ID# (Link to NCBI) |
Population |
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m-Allele |
M-Allele |
m/m (frequency) |
m/M (frequency) |
M/M (frequency) |
Caucasian |
ERBB4_IVS2+67G>C
|
Ireland |
SZ CTR |
- - |
- - |
0 (-) 0 (-) |
0 (-) 0 (-) |
0 (-) 0 (-) |
ERBB4_IVS2+67G>C
|
UK (Cardiff full I) |
SZ CTR |
- - |
- - |
0 (-) 0 (-) |
0 (-) 0 (-) |
0 (-) 0 (-) |
ERBB4_IVS2+67G>C
|
Overlaps with Norton, 2006 UK (Cardiff full I) |
SZ CTR |
- - |
- - |
0 (-) 0 (-) |
0 (-) 0 (-) |
0 (-) 0 (-) |
(-) : Either no data provided, or data otherwise not eligible for inclusion (see methods for details).
Case-Control Studies (by ethnic group) |
|
Genotypes |
Polymorphism ID# (Link to NCBI) |
Population |
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m-Allele |
M-Allele |
m/m (frequency) |
m/M (frequency) |
M/M (frequency) |
Caucasian |
ERBB4_IVS20-50G>A
|
Ireland |
SZ CTR |
- - |
- - |
0 (-) 0 (-) |
0 (-) 0 (-) |
0 (-) 0 (-) |
ERBB4_IVS20-50G>A
|
UK (Cardiff) |
SZ CTR |
0.31 0.30 |
0.69 0.70 |
35 (0.095) 33 (0.090) |
158 (0.429) 155 (0.421) |
175 (0.476) 180 (0.489) |
(-) : Either no data provided, or data otherwise not eligible for inclusion (see methods for details).
Case-Control Studies (by ethnic group) |
|
Genotypes |
Polymorphism ID# (Link to NCBI) |
Population |
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m-Allele |
M-Allele |
m/m (frequency) |
m/M (frequency) |
M/M (frequency) |
Caucasian |
ERBB4_IVS25+63A>G
|
UK (Cardiff) |
SZ CTR |
0.34 0.36 |
0.66 0.64 |
43 (0.117) 48 (0.130) |
165 (0.448) 169 (0.459) |
160 (0.435) 151 (0.410) |
ERBB4_IVS25+63A>G
|
Ireland |
SZ CTR |
- - |
- - |
0 (-) 0 (-) |
0 (-) 0 (-) |
0 (-) 0 (-) |
Case-Control Studies (by ethnic group) |
|
Genotypes |
Polymorphism ID# (Link to NCBI) |
Population |
|
m-Allele |
M-Allele |
m/m (frequency) |
m/M (frequency) |
M/M (frequency) |
Caucasian |
ERBB4_IVS25-92C>T
|
Ireland |
SZ CTR |
- - |
- - |
0 (-) 0 (-) |
0 (-) 0 (-) |
0 (-) 0 (-) |
ERBB4_IVS25-92C>T
|
UK (Cardiff) |
SZ CTR |
0.41 0.40 |
0.59 0.60 |
62 (0.168) 59 (0.160) |
178 (0.484) 177 (0.481) |
128 (0.348) 132 (0.359) |
(-) : Either no data provided, or data otherwise not eligible for inclusion (see methods for details).
Case-Control Studies (by ethnic group) |
|
Genotypes |
Polymorphism ID# (Link to NCBI) |
Population |
|
m-Allele |
M-Allele |
m/m (frequency) |
m/M (frequency) |
M/M (frequency) |
Caucasian |
ERBB4_IVS3+58A>G
|
UK (Cardiff) |
SZ CTR |
0.20 0.23 |
0.80 0.77 |
15 (0.041) 20 (0.054) |
118 (0.321) 130 (0.353) |
235 (0.639) 218 (0.592) |
ERBB4_IVS3+58A>G
|
Ireland |
SZ CTR |
- - |
- - |
0 (-) 0 (-) |
0 (-) 0 (-) |
0 (-) 0 (-) |
Case-Control Studies (by ethnic group) |
|
Genotypes |
Polymorphism ID# (Link to NCBI) |
Population |
|
m-Allele |
M-Allele |
m/m (frequency) |
m/M (frequency) |
M/M (frequency) |
Caucasian |
ERBB4_IVS5-67A>G
|
Ireland |
SZ CTR |
- - |
- - |
0 (-) 0 (-) |
0 (-) 0 (-) |
0 (-) 0 (-) |
ERBB4_IVS5-67A>G
|
UK (Cardiff) |
SZ CTR |
0.38 0.40 |
0.62 0.60 |
53 (0.144) 59 (0.160) |
173 (0.470) 177 (0.481) |
142 (0.386) 132 (0.359) |
(-) : Either no data provided, or data otherwise not eligible for inclusion (see methods for details).
Case-Control Studies (by ethnic group) |
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Genotypes |
Polymorphism ID# (Link to NCBI) |
Population |
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C-Allele |
T-Allele |
C/C (frequency) |
C/T (frequency) |
T/T (frequency) |
Caucasian |
rs1482381
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UK (Cardiff) |
SZ CTR |
0.17 0.15 |
0.83 0.85 |
11 (0.030) 8 (0.022) |
104 (0.283) 94 (0.255) |
253 (0.688) 266 (0.723) |
rs1482381
|
Ireland |
SZ CTR |
- - |
- - |
0 (-) 0 (-) |
0 (-) 0 (-) |
0 (-) 0 (-) |
Case-Control Studies (by ethnic group) |
|
Genotypes |
Polymorphism ID# (Link to NCBI) |
Population |
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m-Allele |
M-Allele |
m/m (frequency) |
m/M (frequency) |
M/M (frequency) |
Caucasian |
rs1905139
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Ireland |
SZ CTR |
- - |
- - |
0 (-) 0 (-) |
0 (-) 0 (-) |
0 (-) 0 (-) |
rs1905139
|
UK (Cardiff) |
SZ CTR |
0.48 0.48 |
0.52 0.52 |
85 (0.231) 85 (0.231) |
184 (0.500) 184 (0.500) |
99 (0.269) 99 (0.269) |
(-) : Either no data provided, or data otherwise not eligible for inclusion (see methods for details).
Case-Control Studies (by ethnic group) |
|
Genotypes |
Polymorphism ID# (Link to NCBI) |
Population |
|
m-Allele |
M-Allele |
m/m (frequency) |
m/M (frequency) |
M/M (frequency) |
Caucasian |
rs1851185
|
UK (Cardiff full II) |
SZ CTR |
- - |
- - |
0 (-) 0 (-) |
0 (-) 0 (-) |
0 (-) 0 (-) |
(-) : Either no data provided, or data otherwise not eligible for inclusion (see methods for details).
Case-Control Studies (by ethnic group) |
|
Genotypes |
Polymorphism ID# (Link to NCBI) |
Population |
|
C-Allele |
T-Allele |
C/C (frequency) |
C/T (frequency) |
T/T (frequency) |
Caucasian |
rs2371277
|
UK (Cardiff full II) |
SZ CTR |
- - |
- - |
0 (-) 0 (-) |
0 (-) 0 (-) |
0 (-) 0 (-) |
(-) : Either no data provided, or data otherwise not eligible for inclusion (see methods for details).
Case-Control Studies (by ethnic group) |
|
Genotypes |
Polymorphism ID# (Link to NCBI) |
Population |
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m-Allele |
M-Allele |
m/m (frequency) |
m/M (frequency) |
M/M (frequency) |
Caucasian |
rs4673629
|
UK (Cardiff full II) |
SZ CTR |
- - |
- - |
0 (-) 0 (-) |
0 (-) 0 (-) |
0 (-) 0 (-) |
(-) : Either no data provided, or data otherwise not eligible for inclusion (see methods for details).
Case-Control Studies (by ethnic group) |
|
Genotypes |
Polymorphism ID# (Link to NCBI) |
Population |
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m-Allele |
M-Allele |
m/m (frequency) |
m/M (frequency) |
M/M (frequency) |
Caucasian |
rs6435661
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UK (Cardiff full II) |
SZ CTR |
- - |
- - |
0 (-) 0 (-) |
0 (-) 0 (-) |
0 (-) 0 (-) |
(-) : Either no data provided, or data otherwise not eligible for inclusion (see methods for details).
Case-Control Studies (by ethnic group) |
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Genotypes |
Polymorphism ID# (Link to NCBI) |
Population |
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m-Allele |
M-Allele |
m/m (frequency) |
m/M (frequency) |
M/M (frequency) |
Caucasian |
rs6705698
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UK (Cardiff full II) |
SZ CTR |
- - |
- - |
0 (-) 0 (-) |
0 (-) 0 (-) |
0 (-) 0 (-) |
(-) : Either no data provided, or data otherwise not eligible for inclusion (see methods for details).
Case-Control Studies (by ethnic group) |
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Genotypes |
Polymorphism ID# (Link to NCBI) |
Population |
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T-Allele |
C-Allele |
T/T (frequency) |
T/C (frequency) |
C/C (frequency) |
Caucasian |
rs6725181
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UK (Cardiff full II) |
SZ CTR |
- - |
- - |
0 (-) 0 (-) |
0 (-) 0 (-) |
0 (-) 0 (-) |
(-) : Either no data provided, or data otherwise not eligible for inclusion (see methods for details).
Case-Control Studies (by ethnic group) |
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Genotypes |
Polymorphism ID# (Link to NCBI) |
Population |
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C-Allele |
T-Allele |
C/C (frequency) |
C/T (frequency) |
T/T (frequency) |
Caucasian |
rs6745717
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UK (Cardiff full II) |
SZ CTR |
- - |
- - |
0 (-) 0 (-) |
0 (-) 0 (-) |
0 (-) 0 (-) |
(-) : Either no data provided, or data otherwise not eligible for inclusion (see methods for details).
Case-Control Studies (by ethnic group) |
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Genotypes |
Polymorphism ID# (Link to NCBI) |
Population |
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G-Allele |
A-Allele |
G/G (frequency) |
G/A (frequency) |
A/A (frequency) |
Caucasian |
rs6752616
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UK (Cardiff full II) |
SZ CTR |
- - |
- - |
0 (-) 0 (-) |
0 (-) 0 (-) |
0 (-) 0 (-) |
(-) : Either no data provided, or data otherwise not eligible for inclusion (see methods for details).
Case-Control Studies (by ethnic group) |
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Genotypes |
Polymorphism ID# (Link to NCBI) |
Population |
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m-Allele |
M-Allele |
m/m (frequency) |
m/M (frequency) |
M/M (frequency) |
Caucasian |
rs6758038
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UK (Cardiff full II) |
SZ CTR |
- - |
- - |
0 (-) 0 (-) |
0 (-) 0 (-) |
0 (-) 0 (-) |
(-) : Either no data provided, or data otherwise not eligible for inclusion (see methods for details).
Case-Control Studies (by ethnic group) |
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Genotypes |
Polymorphism ID# (Link to NCBI) |
Population |
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m-Allele |
M-Allele |
m/m (frequency) |
m/M (frequency) |
M/M (frequency) |
Caucasian |
rs7419602
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UK (Cardiff full II) |
SZ CTR |
- - |
- - |
0 (-) 0 (-) |
0 (-) 0 (-) |
0 (-) 0 (-) |
(-) : Either no data provided, or data otherwise not eligible for inclusion (see methods for details).
Case-Control Studies (by ethnic group) |
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Genotypes |
Polymorphism ID# (Link to NCBI) |
Population |
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m-Allele |
M-Allele |
m/m (frequency) |
m/M (frequency) |
M/M (frequency) |
Caucasian |
rs7424835
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UK (Cardiff full II) |
SZ CTR |
- - |
- - |
0 (-) 0 (-) |
0 (-) 0 (-) |
0 (-) 0 (-) |
(-) : Either no data provided, or data otherwise not eligible for inclusion (see methods for details).
Case-Control Studies (by ethnic group) |
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Genotypes |
Polymorphism ID# (Link to NCBI) |
Population |
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m-Allele |
M-Allele |
m/m (frequency) |
m/M (frequency) |
M/M (frequency) |
Caucasian |
rs7425341
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UK (Cardiff full II) |
SZ CTR |
- - |
- - |
0 (-) 0 (-) |
0 (-) 0 (-) |
0 (-) 0 (-) |
(-) : Either no data provided, or data otherwise not eligible for inclusion (see methods for details).
Case-Control Studies (by ethnic group) |
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Genotypes |
Polymorphism ID# (Link to NCBI) |
Population |
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G-Allele |
T-Allele |
G/G (frequency) |
G/T (frequency) |
T/T (frequency) |
Caucasian |
rs7597007
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UK (Cardiff full II) |
SZ CTR |
- - |
- - |
0 (-) 0 (-) |
0 (-) 0 (-) |
0 (-) 0 (-) |
(-) : Either no data provided, or data otherwise not eligible for inclusion (see methods for details).
Case-Control Studies (by ethnic group) |
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Genotypes |
Polymorphism ID# (Link to NCBI) |
Population |
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m-Allele |
M-Allele |
m/m (frequency) |
m/M (frequency) |
M/M (frequency) |
Caucasian |
rs9288438
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UK (Cardiff full II) |
SZ CTR |
- - |
- - |
0 (-) 0 (-) |
0 (-) 0 (-) |
0 (-) 0 (-) |
(-) : Either no data provided, or data otherwise not eligible for inclusion (see methods for details).
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