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Polymorphism Details     
Back Search Methods Disclaimer Credits
 Study: Vilella, 2007
 Gene: NRG1  (GGF; HGL; HRG; NDF; ARIA; GGF2; HRG1; HRGA; SMDF)  Entrez Gene    View on AlzGene
 Protein: neuregulin 1  (glial growth factor; neu differentiation factor; sensory and motor neuron derived factor; heregulin, alpha (45kD, ERBB2 p185-activator))  ProteinLink
 Chromosome: 8   (View: 1  2  3  4  5  6  7  8  9  10  11  12  13  14  15  16  17  18  19  20  21  22  X  Y  MT)
 Status: Updated 23 November 2010
Meta-Analysis     Gene Overview
Total number of polymorphisms investigated by this study: 18

Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)		 Population   G-Allele A-Allele G/G
(frequency)		 G/A
(frequency)		 A/A
(frequency)
 Caucasian
rs764059 Spain SZ
CTR		 0.16
0.17		 0.84
0.83		 15 (0.025)
18 (0.029)		 158 (0.268)
174 (0.282)		 416 (0.706)
424 (0.688)


Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   A-Allele G-Allele A/A
(frequency)		 A/G
(frequency)		 G/G
(frequency)
 Caucasian
rs3924999 (Gln38Arg) Spain SZ
CTR		 0.42
0.41		 0.58
0.59		 104 (0.177)
103 (0.167)		 287 (0.487)
298 (0.485)		 198 (0.336)
214 (0.348)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)		 Population   G-Allele A-Allele G/G
(frequency)		 G/A
(frequency)		 A/A
(frequency)
 Caucasian
rs1503487 Spain SZ
CTR		 0.31
0.30		 0.69
0.70		 57 (0.097)
55 (0.090)		 252 (0.428)
258 (0.420)		 280 (0.475)
301 (0.490)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)		 Population   T-Allele G-Allele T/T
(frequency)		 T/G
(frequency)		 G/G
(frequency)
 Caucasian
SNP8NRG241930 Spain SZ
CTR		 0.37
0.36		 0.63
0.64		 81 (0.138)
80 (0.130)		 274 (0.465)
283 (0.460)		 234 (0.397)
252 (0.410)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)		 Population   C-Allele T-Allele C/C
(frequency)		 C/T
(frequency)		 T/T
(frequency)
 Caucasian
rs35753505 (SNP8NRG221533) Spain SZ
CTR		 0.36
0.34		 0.64
0.66		 76 (0.129)
71 (0.115)		 271 (0.461)
276 (0.449)		 241 (0.410)
268 (0.436)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)		 Population   G-Allele A-Allele G/G
(frequency)		 G/A
(frequency)		 A/A
(frequency)
 Caucasian
rs901561 Spain SZ
CTR		 0.36
0.35		 0.64
0.65		 76 (0.129)
75 (0.122)		 272 (0.462)
280 (0.455)		 241 (0.409)
260 (0.423)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)		 Population   A-Allele G-Allele A/A
(frequency)		 A/G
(frequency)		 G/G
(frequency)
 Caucasian
rs1503488 Spain SZ
CTR		 0.32
0.31		 0.68
0.69		 60 (0.102)
59 (0.096)		 256 (0.435)
263 (0.428)		 273 (0.463)
293 (0.476)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)		 Population   A-Allele G-Allele A/A
(frequency)		 A/G
(frequency)		 G/G
(frequency)
 Caucasian
rs726908 Spain SZ
CTR		 0.44
0.42		 0.56
0.58		 114 (0.194)
108 (0.176)		 290 (0.492)
300 (0.488)		 185 (0.314)
207 (0.337)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)		 Population   G-Allele A-Allele G/G
(frequency)		 G/A
(frequency)		 A/A
(frequency)
 Caucasian
rs723811 Spain SZ
CTR		 0.17
0.17		 0.83
0.83		 17 (0.029)
18 (0.029)		 166 (0.282)
174 (0.282)		 406 (0.689)
424 (0.688)


Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   C-Allele T-Allele C/C
(frequency)		 C/T
(frequency)		 T/T
(frequency)
 Caucasian
rs4501543 Spain SZ
CTR		 0.46
0.45		 0.54
0.55		 125 (0.212)
125 (0.203)		 292 (0.496)
304 (0.494)		 172 (0.292)
186 (0.302)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   T-Allele G-Allele T/T
(frequency)		 T/G
(frequency)		 G/G
(frequency)
 Caucasian
rs2466061 Spain SZ
CTR		 0.09
0.12		 0.91
0.88		 5 (0.008)
9 (0.015)		 96 (0.163)
130 (0.211)		 488 (0.829)
476 (0.774)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   C-Allele A-Allele C/C
(frequency)		 C/A
(frequency)		 A/A
(frequency)
 Caucasian
rs2466048 Spain SZ
CTR		 0.45
0.44		 0.55
0.56		 119 (0.202)
119 (0.193)		 292 (0.496)
303 (0.493)		 178 (0.302)
193 (0.314)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   C-Allele T-Allele C/C
(frequency)		 C/T
(frequency)		 T/T
(frequency)
 Caucasian
rs2439279 Spain SZ
CTR		 0.48
0.50		 0.52
0.50		 136 (0.231)
154 (0.250)		 294 (0.499)
307 (0.499)		 159 (0.270)
154 (0.250)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   C-Allele T-Allele C/C
(frequency)		 C/T
(frequency)		 T/T
(frequency)
 Caucasian
rs2134619 Spain SZ
CTR		 0.32
0.31		 0.68
0.69		 60 (0.102)
59 (0.096)		 256 (0.435)
263 (0.428)		 273 (0.463)
293 (0.476)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   T-Allele C-Allele T/T
(frequency)		 T/C
(frequency)		 C/C
(frequency)
 Caucasian
rs1393952 Spain SZ
CTR		 0.32
0.30		 0.68
0.70		 60 (0.102)
55 (0.090)		 256 (0.435)
258 (0.420)		 273 (0.463)
301 (0.490)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   G-Allele A-Allele G/G
(frequency)		 G/A
(frequency)		 A/A
(frequency)
 Caucasian
rs1383895 Spain SZ
CTR		 0.43
0.42		 0.57
0.58		 109 (0.185)
108 (0.176)		 289 (0.491)
300 (0.488)		 191 (0.324)
207 (0.337)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   T-Allele C-Allele T/T
(frequency)		 T/C
(frequency)		 C/C
(frequency)
 Caucasian
rs1351510 Spain SZ
CTR		 0.29
0.25		 0.71
0.75		 50 (0.085)
38 (0.062)		 242 (0.411)
231 (0.376)		 297 (0.504)
346 (0.563)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   G-Allele C-Allele G/G
(frequency)		 G/C
(frequency)		 C/C
(frequency)
 Caucasian
rs13263208 (hCV2061466) Spain SZ
CTR		 0.49
0.50		 0.51
0.50		 141 (0.240)
154 (0.250)		 294 (0.500)
308 (0.500)		 153 (0.260)
154 (0.250)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.
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SZGene Stats
Studies: 1727
Genes: 1008
Polymorphisms: 8788
Meta-analyses: 287
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