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Polymorphism Details     
Back Search Methods Disclaimer Credits
 Study: Benzel, 2007
 Gene: NRG1  (GGF; HGL; HRG; NDF; ARIA; GGF2; HRG1; HRGA; SMDF)  Entrez Gene    View on AlzGene
 Protein: neuregulin 1  (glial growth factor; neu differentiation factor; sensory and motor neuron derived factor; heregulin, alpha (45kD, ERBB2 p185-activator))  ProteinLink
 Chromosome: 8   (View: 1  2  3  4  5  6  7  8  9  10  11  12  13  14  15  16  17  18  19  20  21  22  X  Y  MT)
 Status: Updated 23 November 2010
Meta-Analysis     Gene Overview
Total number of polymorphisms investigated by this study: 94

Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)
Population   T-Allele C-Allele T/T
(frequency)
T/C
(frequency)
C/C
(frequency)
 Caucasian
rs6994992 UK SZ
CTR
0.42
0.40
0.58
0.60
69 (0.174)
215 (0.160)
193 (0.487)
644 (0.480)
134 (0.338)
482 (0.359)


Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)
Population   A-Allele G-Allele A/A
(frequency)
A/G
(frequency)
G/G
(frequency)
 Caucasian
rs3924999 (Gln38Arg) UK SZ
CTR
0.39
0.43
0.61
0.57
59 (0.149)
248 (0.185)
188 (0.474)
658 (0.490)
150 (0.378)
436 (0.325)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)
Population   C-Allele A-Allele C/C
(frequency)
C/A
(frequency)
A/A
(frequency)
 Caucasian
rs3735782 UK SZ
CTR
0.42
0.46
0.58
0.54
71 (0.179)
282 (0.210)
193 (0.487)
666 (0.496)
132 (0.333)
394 (0.294)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)
Population   m-Allele M-Allele m/m
(frequency)
m/M
(frequency)
M/M
(frequency)
 Caucasian
rs733230 UK SZ
CTR
0.12
0.11
0.88
0.89
6 (0.015)
16 (0.012)
84 (0.212)
260 (0.194)
306 (0.773)
1066 (0.794)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)
Population   G-Allele A-Allele G/G
(frequency)
G/A
(frequency)
A/A
(frequency)
 Caucasian
rs6988339 UK SZ
CTR
0.43
0.41
0.57
0.59
72 (0.181)
230 (0.171)
194 (0.489)
651 (0.485)
131 (0.330)
461 (0.344)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)
Population   A-Allele G-Allele A/A
(frequency)
A/G
(frequency)
G/G
(frequency)
 Caucasian
rs4733306 UK SZ
CTR
0.23
0.22
0.77
0.78
21 (0.053)
66 (0.049)
141 (0.356)
463 (0.345)
234 (0.591)
814 (0.606)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)
Population   T-Allele G-Allele T/T
(frequency)
T/G
(frequency)
G/G
(frequency)
 Caucasian
rs2954041 UK SZ
CTR
0.02
0.01
0.98
0.99
0 (0.000)
0 (0.000)
12 (0.030)
37 (0.028)
384 (0.970)
1304 (0.972)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)
Population   A-Allele G-Allele A/A
(frequency)
A/G
(frequency)
G/G
(frequency)
 Caucasian
rs2439272 UK SZ
CTR
0.41
0.42
0.59
0.58
66 (0.167)
238 (0.177)
191 (0.484)
654 (0.488)
138 (0.349)
449 (0.335)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)
Population   A-Allele T-Allele A/A
(frequency)
A/T
(frequency)
T/T
(frequency)
 Caucasian
rs1503489 UK SZ
CTR
0.33
0.37
0.67
0.63
43 (0.109)
180 (0.134)
175 (0.442)
623 (0.465)
178 (0.449)
538 (0.401)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)
Population   G-Allele C-Allele G/G
(frequency)
G/C
(frequency)
C/C
(frequency)
 Caucasian
rs1354335 UK SZ
CTR
0.16
0.17
0.84
0.83
10 (0.025)
38 (0.028)
106 (0.268)
374 (0.278)
280 (0.707)
931 (0.693)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)
Population   G-Allele A-Allele G/G
(frequency)
G/A
(frequency)
A/A
(frequency)
 Caucasian
rs10503899 UK SZ
CTR
0.44
0.42
0.56
0.58
78 (0.197)
242 (0.180)
196 (0.495)
656 (0.489)
122 (0.308)
444 (0.331)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)
Population   G-Allele A-Allele G/G
(frequency)
G/A
(frequency)
A/A
(frequency)
 Caucasian
rs1948098 UK SZ
CTR
0.35
0.32
0.65
0.68
49 (0.124)
138 (0.103)
180 (0.455)
584 (0.435)
167 (0.422)
620 (0.462)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)
Population   C-Allele T-Allele C/C
(frequency)
C/T
(frequency)
T/T
(frequency)
 Caucasian
rs776401 UK SZ
CTR
0.31
0.36
0.69
0.64
38 (0.096)
178 (0.133)
169 (0.427)
622 (0.463)
189 (0.477)
542 (0.404)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)
Population   C-Allele T-Allele C/C
(frequency)
C/T
(frequency)
T/T
(frequency)
 Caucasian
rs776382 UK SZ
CTR
0.32
0.29
0.68
0.71
41 (0.104)
116 (0.087)
173 (0.437)
557 (0.415)
182 (0.460)
668 (0.498)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)
Population   G-Allele A-Allele G/G
(frequency)
G/A
(frequency)
A/A
(frequency)
 Caucasian
rs4733376 UK SZ
CTR
0.12
0.09
0.88
0.91
6 (0.015)
11 (0.008)
85 (0.215)
223 (0.166)
305 (0.770)
1107 (0.826)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)
Population   C-Allele A-Allele C/C
(frequency)
C/A
(frequency)
A/A
(frequency)
 Caucasian
rs2976525 UK SZ
CTR
0.08
0.09
0.92
0.91
3 (0.008)
11 (0.008)
61 (0.154)
222 (0.165)
332 (0.838)
1109 (0.826)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)
Population   T-Allele C-Allele T/T
(frequency)
T/C
(frequency)
C/C
(frequency)
 Caucasian
rs2466049 UK SZ
CTR
0.10
0.08
0.90
0.92
4 (0.010)
8 (0.006)
68 (0.171)
186 (0.139)
325 (0.819)
1148 (0.855)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)
Population   T-Allele C-Allele T/T
(frequency)
T/C
(frequency)
C/C
(frequency)
 Caucasian
rs1393952 UK SZ
CTR
0.23
0.24
0.77
0.76
20 (0.051)
76 (0.057)
138 (0.349)
486 (0.362)
237 (0.600)
781 (0.582)


Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)
Population   m-Allele M-Allele m/m
(frequency)
m/M
(frequency)
M/M
(frequency)
 Caucasian
rs10081436 UK SZ
CTR
0.05
0.06
0.95
0.94
1 (0.003)
5 (0.004)
40 (0.101)
148 (0.110)
355 (0.896)
1190 (0.886)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)
Population   T-Allele C-Allele T/T
(frequency)
T/C
(frequency)
C/C
(frequency)
 Caucasian
rs10087952 UK SZ
CTR
0.22
0.23
0.78
0.77
19 (0.048)
69 (0.051)
136 (0.343)
470 (0.350)
241 (0.609)
804 (0.599)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)
Population   G-Allele A-Allele G/G
(frequency)
G/A
(frequency)
A/A
(frequency)
 Caucasian
rs10092347 UK SZ
CTR
0.24
0.25
0.76
0.75
23 (0.058)
84 (0.063)
146 (0.369)
504 (0.376)
227 (0.573)
754 (0.562)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)
Population   m-Allele M-Allele m/m
(frequency)
m/M
(frequency)
M/M
(frequency)
 Caucasian
rs10099542 UK SZ
CTR
0.27
0.26
0.73
0.74
28 (0.071)
89 (0.066)
155 (0.391)
513 (0.383)
213 (0.538)
739 (0.551)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)
Population   A-Allele G-Allele A/A
(frequency)
A/G
(frequency)
G/G
(frequency)
 Caucasian
rs10103976 UK SZ
CTR
0.33
0.35
0.67
0.65
42 (0.106)
165 (0.123)
174 (0.441)
611 (0.456)
179 (0.453)
565 (0.421)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)
Population   m-Allele M-Allele m/m
(frequency)
m/M
(frequency)
M/M
(frequency)
 Caucasian
rs10105300 UK SZ
CTR
0.07
0.09
0.93
0.91
2 (0.005)
10 (0.007)
52 (0.131)
216 (0.161)
342 (0.864)
1116 (0.832)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)
Population   m-Allele M-Allele m/m
(frequency)
m/M
(frequency)
M/M
(frequency)
 Caucasian
rs10503897 UK SZ
CTR
0.42
0.45
0.58
0.55
71 (0.180)
278 (0.207)
193 (0.489)
666 (0.496)
131 (0.332)
399 (0.297)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)
Population   G-Allele T-Allele G/G
(frequency)
G/T
(frequency)
T/T
(frequency)
 Caucasian
rs10503903 UK SZ
CTR
0.06
0.06
0.94
0.94
2 (0.005)
5 (0.004)
47 (0.118)
154 (0.115)
348 (0.877)
1183 (0.882)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)
Population   A-Allele G-Allele A/A
(frequency)
A/G
(frequency)
G/G
(frequency)
 Caucasian
rs1381866 UK SZ
CTR
0.30
0.32
0.70
0.68
36 (0.091)
137 (0.102)
167 (0.422)
583 (0.434)
193 (0.487)
622 (0.463)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)
Population   T-Allele C-Allele T/T
(frequency)
T/C
(frequency)
C/C
(frequency)
 Caucasian
rs1381871 UK SZ
CTR
0.27
0.27
0.73
0.73
28 (0.071)
99 (0.074)
155 (0.391)
532 (0.396)
213 (0.538)
711 (0.530)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)
Population   T-Allele C-Allele T/T
(frequency)
T/C
(frequency)
C/C
(frequency)
 Caucasian
rs1383887 UK SZ
CTR
0.49
0.46
0.51
0.54
94 (0.237)
287 (0.214)
198 (0.499)
667 (0.497)
105 (0.264)
388 (0.289)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)
Population   A-Allele G-Allele A/A
(frequency)
A/G
(frequency)
G/G
(frequency)
 Caucasian
rs1383959 UK SZ
CTR
0.31
0.34
0.69
0.66
38 (0.096)
154 (0.115)
170 (0.429)
601 (0.448)
188 (0.475)
587 (0.437)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)
Population   A-Allele C-Allele A/A
(frequency)
A/C
(frequency)
C/C
(frequency)
 Caucasian
rs1383961 UK SZ
CTR
0.32
0.35
0.68
0.65
41 (0.104)
164 (0.122)
173 (0.437)
610 (0.455)
182 (0.460)
568 (0.423)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)
Population   m-Allele M-Allele m/m
(frequency)
m/M
(frequency)
M/M
(frequency)
 Caucasian
rs1386437 UK SZ
CTR
0.37
0.42
0.63
0.58
55 (0.139)
233 (0.174)
185 (0.468)
652 (0.486)
155 (0.392)
456 (0.340)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)
Population   C-Allele A-Allele C/C
(frequency)
C/A
(frequency)
A/A
(frequency)
 Caucasian
rs1481615 UK SZ
CTR
0.39
0.37
0.61
0.63
59 (0.149)
179 (0.133)
188 (0.475)
623 (0.464)
149 (0.376)
540 (0.402)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)
Population   T-Allele C-Allele T/T
(frequency)
T/C
(frequency)
C/C
(frequency)
 Caucasian
rs1481619 UK SZ
CTR
0.33
0.30
0.67
0.70
42 (0.106)
118 (0.088)
174 (0.439)
560 (0.417)
180 (0.455)
664 (0.495)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)
Population   A-Allele T-Allele A/A
(frequency)
A/T
(frequency)
T/T
(frequency)
 Caucasian
rs1481748 UK SZ
CTR
0.26
0.24
0.74
0.76
26 (0.066)
77 (0.057)
151 (0.381)
489 (0.365)
219 (0.553)
775 (0.578)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)
Population   T-Allele C-Allele T/T
(frequency)
T/C
(frequency)
C/C
(frequency)
 Caucasian
rs1481758 UK SZ
CTR
0.22
0.21
0.78
0.79
19 (0.048)
62 (0.046)
136 (0.343)
453 (0.337)
241 (0.609)
828 (0.617)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)
Population   A-Allele G-Allele A/A
(frequency)
A/G
(frequency)
G/G
(frequency)
 Caucasian
rs1487152 UK SZ
CTR
0.50
0.48
0.50
0.52
98 (0.247)
310 (0.231)
198 (0.500)
670 (0.499)
100 (0.253)
362 (0.270)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)
Population   C-Allele A-Allele C/C
(frequency)
C/A
(frequency)
A/A
(frequency)
 Caucasian
rs1503497 UK SZ
CTR
0.23
0.25
0.77
0.75
21 (0.053)
87 (0.065)
141 (0.356)
509 (0.379)
234 (0.591)
747 (0.556)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)
Population   T-Allele C-Allele T/T
(frequency)
T/C
(frequency)
C/C
(frequency)
 Caucasian
rs167859 UK SZ
CTR
0.20
0.17
0.80
0.83
16 (0.040)
41 (0.031)
127 (0.321)
387 (0.288)
253 (0.639)
914 (0.681)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)
Population   T-Allele C-Allele T/T
(frequency)
T/C
(frequency)
C/C
(frequency)
 Caucasian
rs1699128 UK SZ
CTR
0.10
0.09
0.90
0.91
4 (0.010)
11 (0.008)
74 (0.187)
222 (0.165)
317 (0.803)
1109 (0.826)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)
Population   G-Allele T-Allele G/G
(frequency)
G/T
(frequency)
T/T
(frequency)
 Caucasian
rs1948097 UK SZ
CTR
0.32
0.35
0.68
0.65
42 (0.106)
167 (0.124)
174 (0.438)
613 (0.457)
181 (0.456)
562 (0.419)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)
Population   T-Allele A-Allele T/T
(frequency)
T/A
(frequency)
A/A
(frequency)
 Caucasian
rs2347499 UK SZ
CTR
0.30
0.31
0.70
0.69
36 (0.091)
127 (0.095)
166 (0.419)
572 (0.427)
194 (0.490)
642 (0.479)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)
Population   A-Allele G-Allele A/A
(frequency)
A/G
(frequency)
G/G
(frequency)
 Caucasian
rs2439282 UK SZ
CTR
0.12
0.10
0.88
0.90
6 (0.015)
13 (0.010)
86 (0.217)
240 (0.179)
304 (0.768)
1089 (0.811)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)
Population   T-Allele C-Allele T/T
(frequency)
T/C
(frequency)
C/C
(frequency)
 Caucasian
rs2439319 UK SZ
CTR
0.07
0.10
0.93
0.90
2 (0.005)
14 (0.010)
55 (0.139)
247 (0.184)
339 (0.856)
1081 (0.806)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)
Population   T-Allele G-Allele T/T
(frequency)
T/G
(frequency)
G/G
(frequency)
 Caucasian
rs2439321 UK SZ
CTR
0.40
0.43
0.60
0.57
64 (0.162)
252 (0.188)
191 (0.482)
659 (0.491)
141 (0.356)
430 (0.321)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)
Population   C-Allele T-Allele C/C
(frequency)
C/T
(frequency)
T/T
(frequency)
 Caucasian
rs2466059 UK SZ
CTR
0.11
0.09
0.89
0.91
5 (0.013)
12 (0.009)
78 (0.196)
229 (0.171)
314 (0.791)
1101 (0.820)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)
Population   T-Allele A-Allele T/T
(frequency)
T/A
(frequency)
A/A
(frequency)
 Caucasian
rs2466071 UK SZ
CTR
0.49
0.49
0.51
0.51
96 (0.242)
325 (0.242)
198 (0.500)
671 (0.500)
102 (0.258)
346 (0.258)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)
Population   m-Allele M-Allele m/m
(frequency)
m/M
(frequency)
M/M
(frequency)
 Caucasian
rs2466098 UK SZ
CTR
0.45
0.42
0.55
0.58
82 (0.207)
238 (0.177)
196 (0.495)
654 (0.487)
118 (0.298)
450 (0.335)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)
Population   m-Allele M-Allele m/m
(frequency)
m/M
(frequency)
M/M
(frequency)
 Caucasian
rs2683768 UK SZ
CTR
0.49
0.46
0.51
0.54
97 (0.245)
282 (0.210)
198 (0.500)
666 (0.497)
101 (0.255)
393 (0.293)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)
Population   G-Allele A-Allele G/G
(frequency)
G/A
(frequency)
A/A
(frequency)
 Caucasian
rs2881472 UK SZ
CTR
0.46
0.46
0.54
0.54
82 (0.208)
285 (0.212)
196 (0.496)
667 (0.497)
117 (0.296)
390 (0.291)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)
Population   G-Allele C-Allele G/G
(frequency)
G/C
(frequency)
C/C
(frequency)
 Caucasian
rs2881651 UK SZ
CTR
0.34
0.37
0.66
0.63
47 (0.119)
179 (0.133)
179 (0.452)
622 (0.463)
170 (0.429)
541 (0.403)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)
Population   T-Allele C-Allele T/T
(frequency)
T/C
(frequency)
C/C
(frequency)
 Caucasian
rs2919379 UK SZ
CTR
0.09
0.12
0.91
0.88
3 (0.008)
19 (0.014)
67 (0.170)
282 (0.210)
325 (0.823)
1040 (0.776)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)
Population   A-Allele G-Allele A/A
(frequency)
A/G
(frequency)
G/G
(frequency)
 Caucasian
rs2919385 UK SZ
CTR
0.01
0.00
0.99
1.00
0 (0.000)
0 (0.000)
9 (0.023)
9 (0.007)
387 (0.977)
1333 (0.993)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)
Population   A-Allele G-Allele A/A
(frequency)
A/G
(frequency)
G/G
(frequency)
 Caucasian
rs327386 UK SZ
CTR
0.19
0.17
0.81
0.83
14 (0.035)
37 (0.028)
120 (0.303)
373 (0.278)
262 (0.662)
932 (0.694)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)
Population   T-Allele A-Allele T/T
(frequency)
T/A
(frequency)
A/A
(frequency)
 Caucasian
rs327412 UK SZ
CTR
0.20
0.18
0.80
0.82
16 (0.040)
43 (0.032)
128 (0.323)
393 (0.293)
252 (0.636)
906 (0.675)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)
Population   C-Allele T-Allele C/C
(frequency)
C/T
(frequency)
T/T
(frequency)
 Caucasian
rs3757928 UK SZ
CTR
0.02
0.02
0.98
0.98
0 (0.000)
0 (0.000)
15 (0.038)
41 (0.031)
381 (0.962)
1301 (0.969)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)
Population   m-Allele M-Allele m/m
(frequency)
m/M
(frequency)
M/M
(frequency)
 Caucasian
rs41404249 UK SZ
CTR
0.12
0.09
0.88
0.91
6 (0.015)
10 (0.007)
84 (0.212)
211 (0.157)
306 (0.773)
1121 (0.835)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)
Population   A-Allele C-Allele A/A
(frequency)
A/C
(frequency)
C/C
(frequency)
 Caucasian
rs4316112 UK SZ
CTR
0.27
0.24
0.73
0.76
28 (0.071)
78 (0.058)
155 (0.392)
491 (0.366)
212 (0.537)
773 (0.576)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)
Population   A-Allele G-Allele A/A
(frequency)
A/G
(frequency)
G/G
(frequency)
 Caucasian
rs4521723 UK SZ
CTR
0.24
0.25
0.76
0.75
22 (0.056)
86 (0.064)
143 (0.361)
508 (0.379)
231 (0.583)
748 (0.557)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)
Population   A-Allele G-Allele A/A
(frequency)
A/G
(frequency)
G/G
(frequency)
 Caucasian
rs4733094 UK SZ
CTR
0.26
0.24
0.74
0.76
28 (0.071)
79 (0.059)
154 (0.388)
494 (0.368)
215 (0.542)
769 (0.573)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)
Population   G-Allele C-Allele G/G
(frequency)
G/C
(frequency)
C/C
(frequency)
 Caucasian
rs4733295 UK SZ
CTR
0.49
0.47
0.51
0.53
97 (0.245)
296 (0.221)
198 (0.500)
669 (0.499)
101 (0.255)
377 (0.281)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)
Population   G-Allele C-Allele G/G
(frequency)
G/C
(frequency)
C/C
(frequency)
 Caucasian
rs4733298 UK SZ
CTR
0.29
0.29
0.71
0.71
33 (0.083)
115 (0.086)
163 (0.411)
556 (0.414)
201 (0.506)
671 (0.500)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)
Population   C-Allele G-Allele C/C
(frequency)
C/G
(frequency)
G/G
(frequency)
 Caucasian
rs4733302 UK SZ
CTR
0.05
0.06
0.95
0.94
1 (0.003)
6 (0.004)
37 (0.093)
161 (0.120)
358 (0.904)
1175 (0.876)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)
Population   T-Allele C-Allele T/T
(frequency)
T/C
(frequency)
C/C
(frequency)
 Caucasian
rs4733346 UK SZ
CTR
0.11
0.12
0.89
0.88
5 (0.013)
19 (0.014)
80 (0.202)
283 (0.211)
311 (0.785)
1040 (0.775)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)
Population   T-Allele C-Allele T/T
(frequency)
T/C
(frequency)
C/C
(frequency)
 Caucasian
rs4733348 UK SZ
CTR
0.17
0.20
0.83
0.80
11 (0.028)
53 (0.039)
112 (0.283)
426 (0.317)
273 (0.689)
863 (0.643)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)
Population   T-Allele A-Allele T/T
(frequency)
T/A
(frequency)
A/A
(frequency)
 Caucasian
rs6468061 UK SZ
CTR
0.15
0.13
0.85
0.87
9 (0.023)
23 (0.017)
99 (0.250)
305 (0.227)
288 (0.727)
1014 (0.756)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)
Population   T-Allele C-Allele T/T
(frequency)
T/C
(frequency)
C/C
(frequency)
 Caucasian
rs6468111 UK SZ
CTR
0.37
0.38
0.63
0.62
54 (0.136)
190 (0.141)
185 (0.467)
630 (0.469)
157 (0.396)
523 (0.389)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)
Population   T-Allele G-Allele T/T
(frequency)
T/G
(frequency)
G/G
(frequency)
 Caucasian
rs6983573 UK SZ
CTR
0.18
0.18
0.82
0.82
13 (0.033)
42 (0.031)
116 (0.293)
390 (0.290)
267 (0.674)
911 (0.678)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)
Population   C-Allele T-Allele C/C
(frequency)
C/T
(frequency)
T/T
(frequency)
 Caucasian
rs6992010 UK SZ
CTR
0.12
0.14
0.88
0.86
6 (0.015)
25 (0.019)
83 (0.210)
317 (0.236)
307 (0.775)
1000 (0.745)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)
Population   C-Allele T-Allele C/C
(frequency)
C/T
(frequency)
T/T
(frequency)
 Caucasian
rs6992907 UK SZ
CTR
0.43
0.39
0.57
0.61
74 (0.187)
209 (0.156)
194 (0.490)
641 (0.478)
128 (0.323)
492 (0.367)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)
Population   m-Allele M-Allele m/m
(frequency)
m/M
(frequency)
M/M
(frequency)
 Caucasian
rs6995261 UK SZ
CTR
0.45
0.44
0.55
0.56
79 (0.199)
263 (0.196)
196 (0.495)
662 (0.493)
121 (0.306)
417 (0.311)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)
Population   T-Allele A-Allele T/T
(frequency)
T/A
(frequency)
A/A
(frequency)
 Caucasian
rs6997612 UK SZ
CTR
0.22
0.22
0.78
0.78
20 (0.051)
66 (0.049)
137 (0.346)
464 (0.346)
239 (0.604)
812 (0.605)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)
Population   T-Allele C-Allele T/T
(frequency)
T/C
(frequency)
C/C
(frequency)
 Caucasian
rs7000590 UK SZ
CTR
0.27
0.26
0.73
0.74
29 (0.073)
90 (0.067)
157 (0.396)
516 (0.385)
210 (0.530)
736 (0.548)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)
Population   C-Allele T-Allele C/C
(frequency)
C/T
(frequency)
T/T
(frequency)
 Caucasian
rs7000656 UK SZ
CTR
0.13
0.12
0.87
0.88
6 (0.015)
20 (0.015)
88 (0.222)
285 (0.212)
302 (0.763)
1038 (0.773)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)
Population   m-Allele M-Allele m/m
(frequency)
m/M
(frequency)
M/M
(frequency)
 Caucasian
rs7002924 UK SZ
CTR
0.38
0.36
0.62
0.64
57 (0.144)
173 (0.129)
186 (0.470)
618 (0.461)
153 (0.386)
551 (0.411)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)
Population   G-Allele A-Allele G/G
(frequency)
G/A
(frequency)
A/A
(frequency)
 Caucasian
rs7003184 UK SZ
CTR
0.23
0.26
0.77
0.74
22 (0.056)
90 (0.067)
142 (0.359)
515 (0.384)
232 (0.586)
737 (0.549)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)
Population   G-Allele A-Allele G/G
(frequency)
G/A
(frequency)
A/A
(frequency)
 Caucasian
rs756266 UK SZ
CTR
0.33
0.30
0.67
0.70
43 (0.109)
121 (0.090)
175 (0.443)
564 (0.420)
177 (0.448)
657 (0.490)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)
Population   C-Allele T-Allele C/C
(frequency)
C/T
(frequency)
T/T
(frequency)
 Caucasian
rs776398 UK SZ
CTR
0.44
0.40
0.56
0.60
78 (0.197)
220 (0.164)
195 (0.492)
647 (0.482)
123 (0.311)
475 (0.354)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)
Population   A-Allele G-Allele A/A
(frequency)
A/G
(frequency)
G/G
(frequency)
 Caucasian
rs7818040 UK SZ
CTR
0.01
0.02
0.99
0.98
0 (0.000)
1 (0.001)
11 (0.028)
65 (0.048)
385 (0.972)
1276 (0.951)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)
Population   T-Allele G-Allele T/T
(frequency)
T/G
(frequency)
G/G
(frequency)
 Caucasian
rs7821017 UK SZ
CTR
0.21
0.26
0.79
0.74
18 (0.046)
91 (0.068)
133 (0.337)
516 (0.385)
244 (0.618)
735 (0.548)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)
Population   A-Allele G-Allele A/A
(frequency)
A/G
(frequency)
G/G
(frequency)
 Caucasian
rs7824399 UK SZ
CTR
0.37
0.37
0.63
0.63
54 (0.136)
183 (0.136)
185 (0.467)
625 (0.466)
157 (0.396)
534 (0.398)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)
Population   A-Allele G-Allele A/A
(frequency)
A/G
(frequency)
G/G
(frequency)
 Caucasian
rs7827456 UK SZ
CTR
0.31
0.32
0.69
0.68
39 (0.098)
135 (0.101)
170 (0.429)
582 (0.434)
187 (0.472)
625 (0.466)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)
Population   A-Allele T-Allele A/A
(frequency)
A/T
(frequency)
T/T
(frequency)
 Caucasian
rs7827460 UK SZ
CTR
0.27
0.28
0.73
0.72
29 (0.073)
103 (0.077)
156 (0.394)
538 (0.401)
211 (0.533)
701 (0.522)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)
Population   m-Allele M-Allele m/m
(frequency)
m/M
(frequency)
M/M
(frequency)
 Caucasian
rs7829669 UK SZ
CTR
0.14
0.12
0.86
0.88
8 (0.020)
21 (0.016)
98 (0.248)
293 (0.218)
289 (0.732)
1028 (0.766)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)
Population   C-Allele G-Allele C/C
(frequency)
C/G
(frequency)
G/G
(frequency)
 Caucasian
rs7835688 UK SZ
CTR
0.46
0.43
0.54
0.57
84 (0.212)
249 (0.186)
197 (0.496)
658 (0.490)
116 (0.292)
435 (0.324)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)
Population   G-Allele A-Allele G/G
(frequency)
G/A
(frequency)
A/A
(frequency)
 Caucasian
rs7839411 UK SZ
CTR
0.07
0.07
0.93
0.93
2 (0.005)
7 (0.005)
55 (0.139)
180 (0.134)
338 (0.856)
1155 (0.861)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)
Population   m-Allele M-Allele m/m
(frequency)
m/M
(frequency)
M/M
(frequency)
 Caucasian
rs7843578 UK SZ
CTR
0.22
0.23
0.78
0.77
20 (0.051)
69 (0.051)
138 (0.348)
472 (0.352)
238 (0.601)
801 (0.597)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)
Population   G-Allele A-Allele G/G
(frequency)
G/A
(frequency)
A/A
(frequency)
 Caucasian
rs9297189 UK SZ
CTR
0.38
0.41
0.62
0.59
57 (0.144)
227 (0.169)
186 (0.470)
650 (0.484)
153 (0.386)
465 (0.346)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)
Population   A-Allele C-Allele A/A
(frequency)
A/C
(frequency)
C/C
(frequency)
 Caucasian
rs967205 UK SZ
CTR
0.11
0.09
0.89
0.91
5 (0.013)
12 (0.009)
79 (0.199)
230 (0.171)
312 (0.788)
1100 (0.820)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)
Population   A-Allele G-Allele A/A
(frequency)
A/G
(frequency)
G/G
(frequency)
 Caucasian
rs983944 UK SZ
CTR
0.22
0.21
0.78
0.79
19 (0.048)
60 (0.045)
135 (0.341)
447 (0.333)
242 (0.611)
835 (0.622)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)
Population   C-Allele T-Allele C/C
(frequency)
C/T
(frequency)
T/T
(frequency)
 Caucasian
rs9918832 UK SZ
CTR
0.24
0.23
0.76
0.77
24 (0.061)
71 (0.053)
146 (0.369)
474 (0.353)
226 (0.571)
797 (0.594)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)
Population   m-Allele M-Allele m/m
(frequency)
m/M
(frequency)
M/M
(frequency)
 Caucasian
rs-GSK11536598 UK SZ
CTR
0.04
0.05
0.96
0.95
1 (0.003)
4 (0.003)
32 (0.081)
131 (0.098)
363 (0.917)
1207 (0.899)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)
Population   m-Allele M-Allele m/m
(frequency)
m/M
(frequency)
M/M
(frequency)
 Caucasian
rs-GSK11536599 UK SZ
CTR
0.39
0.37
0.61
0.63
60 (0.152)
184 (0.137)
188 (0.475)
626 (0.466)
148 (0.374)
532 (0.396)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)
Population   m-Allele M-Allele m/m
(frequency)
m/M
(frequency)
M/M
(frequency)
 Caucasian
rs-GSK11536600 UK SZ
CTR
0.33
0.36
0.67
0.64
44 (0.111)
170 (0.127)
176 (0.444)
615 (0.458)
176 (0.444)
557 (0.415)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.
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Polymorphisms: 8788
Meta-analyses: 287
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