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Polymorphism Details     
Back Search Methods Disclaimer Credits
 Study: Shiota, 2008
 Gene: NRG1  (GGF; HGL; HRG; NDF; ARIA; GGF2; HRG1; HRGA; SMDF)  Entrez Gene    View on AlzGene
 Protein: neuregulin 1  (glial growth factor; neu differentiation factor; sensory and motor neuron derived factor; heregulin, alpha (45kD, ERBB2 p185-activator))  ProteinLink
 Chromosome: 8   (View: 1  2  3  4  5  6  7  8  9  10  11  12  13  14  15  16  17  18  19  20  21  22  X  Y  MT)
 Status: Updated 23 November 2010
Meta-Analysis     Gene Overview
Total number of polymorphisms investigated by this study: 13

Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)		 Population   A-Allele G-Allele A/A
(frequency)		 A/G
(frequency)		 G/G
(frequency)
 Asian
rs3924999 (Gln38Arg) Japan SZ
CTR		 0.79
0.77		 0.21
0.23		 254 (0.611)
309 (0.601)		 149 (0.358)
177 (0.344)		 13 (0.031)
28 (0.054)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)		 Population   T-Allele G-Allele T/T
(frequency)		 T/G
(frequency)		 G/G
(frequency)
 Asian
SNP8NRG241930 Japan SZ
CTR		 0.12
0.11		 0.88
0.89		 6 (0.014)
8 (0.015)		 85 (0.205)
99 (0.191)		 323 (0.780)
411 (0.793)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)		 Population   C-Allele T-Allele C/C
(frequency)		 C/T
(frequency)		 T/T
(frequency)
 Asian
rs35753505 (SNP8NRG221533) Japan SZ
CTR		 0.54
0.53		 0.46
0.47		 120 (0.291)
154 (0.301)		 202 (0.490)
235 (0.460)		 90 (0.218)
122 (0.239)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)		 Population   G-Allele A-Allele G/G
(frequency)		 G/A
(frequency)		 A/A
(frequency)
 Asian
rs6988339 Japan SZ
CTR		 0.52
0.47		 0.48
0.53		 107 (0.257)
119 (0.229)		 215 (0.517)
252 (0.485)		 94 (0.226)
149 (0.287)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)		 Population   T-Allele G-Allele T/T
(frequency)		 T/G
(frequency)		 G/G
(frequency)
 Asian
rs2954041 Japan SZ
CTR		 0.36
0.32		 0.64
0.68		 53 (0.134)
58 (0.118)		 178 (0.449)
194 (0.395)		 165 (0.417)
239 (0.487)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)		 Population   A-Allele G-Allele A/A
(frequency)		 A/G
(frequency)		 G/G
(frequency)
 Asian
rs2439272 Japan SZ
CTR		 0.20
0.19		 0.80
0.81		 22 (0.054)
21 (0.042)		 122 (0.298)
153 (0.303)		 265 (0.648)
331 (0.655)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)		 Population   n.a.-Allele n.a.-Allele n.a./n.a.
(frequency)		 n.a./n.a.
(frequency)		 n.a./n.a.
(frequency)
 Asian
478B14-848 Japan SZ
CTR		 -
-		 -
-		 0 (-)
0 (-)		 0 (-)
0 (-)		 0 (-)
0 (-)
(-) :  Either no data provided, or data otherwise not eligible for inclusion (see methods for details).

Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)		 Population   n.a.-Allele n.a.-Allele n.a./n.a.
(frequency)		 n.a./n.a.
(frequency)		 n.a./n.a.
(frequency)
 Asian
420M9-1395 Japan SZ
CTR		 -
-		 -
-		 0 (-)
0 (-)		 0 (-)
0 (-)		 0 (-)
0 (-)
(-) :  Either no data provided, or data otherwise not eligible for inclusion (see methods for details).

Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)		 Population   T-Allele C-Allele T/T
(frequency)		 T/C
(frequency)		 C/C
(frequency)
 Asian
rs6994992 (SNP8NRG243177) Japan SZ
CTR		 0.52
0.53		 0.48
0.47		 119 (0.288)
151 (0.292)		 193 (0.467)
246 (0.476)		 101 (0.245)
120 (0.232)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)		 Population   C-Allele T-Allele C/C
(frequency)		 C/T
(frequency)		 T/T
(frequency)
 Asian
rs1081062 Japan SZ
CTR		 0.12
0.12		 0.88
0.88		 4 (0.010)
5 (0.010)		 91 (0.220)
114 (0.224)		 318 (0.770)
390 (0.766)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)		 Population   T-Allele C-Allele T/T
(frequency)		 T/C
(frequency)		 C/C
(frequency)
 Asian
rs2466058 Japan SZ
CTR		 0.11
0.13		 0.89
0.87		 5 (0.012)
5 (0.010)		 76 (0.188)
120 (0.240)		 323 (0.800)
376 (0.750)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)		 Population   T-Allele A-Allele T/T
(frequency)		 T/A
(frequency)		 A/A
(frequency)
 Asian
rs7823899 Japan SZ
CTR		 -
-		 -
-		 0 (-)
0 (-)		 0 (-)
0 (-)		 0 (-)
0 (-)
(-) :  Either no data provided, or data otherwise not eligible for inclusion (see methods for details).

Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)		 Population   A-Allele G-Allele A/A
(frequency)		 A/G
(frequency)		 G/G
(frequency)
 Asian
rs2919381 Japan SZ
CTR		 0.44
0.44		 0.56
0.56		 90 (0.217)
102 (0.196)		 187 (0.451)
252 (0.485)		 138 (0.333)
166 (0.319)
SZGene Recent Updates
SZGene Stats
Studies: 1727
Genes: 1008
Polymorphisms: 8788
Meta-analyses: 287
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